Related references
Note: Only part of the references are listed.Increased demand for NAD+ relative to ATP drives aerobic glycolysis
Alba Luengo et al.
MOLECULAR CELL (2021)
Blocking Aerobic Glycolysis by Targeting Pyruvate Dehydrogenase Kinase in Combination with EGFR TKI and Ionizing Radiation Increases Therapeutic Effect in Non-Small Cell Lung Cancer Cells
Sissel E. Dyrstad et al.
CANCERS (2021)
?Labile? heme critically regulates mitochondrial biogenesis through the transcriptional co-activator Hap4p in Saccharomyces cerevisiae
Cyrielle L. Bouchez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Warburg and Beyond: The Power of Mitochondrial Metabolism to Collaborate or Replace Fermentative Glycolysis in Cancer
Shamir Cassim et al.
CANCERS (2020)
The Warburg Effect in Yeast: Repression of Mitochondrial Metabolism Is Not a Prerequisite to Promote Cell Proliferation
Cyrielle L. Bouchez et al.
FRONTIERS IN ONCOLOGY (2020)
PGC-1 alpha as a Biomarker of Physical Activity-Protective Effect on Colorectal Cancer
Fernanda de Souza-Teixeira et al.
CANCER PREVENTION RESEARCH (2018)
Expression and role of nuclear receptor coregulators in colorectal cancer
Mouna Triki et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2017)
Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1
Ionica Masgras et al.
CELL REPORTS (2017)
The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells
Ionica Masgras et al.
FRONTIERS IN ONCOLOGY (2017)
Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer
Shawn M. Davidson et al.
CELL METABOLISM (2016)
Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation
Katrin Birkenmeier et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
Chi Luo et al.
NATURE (2016)
Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma
Edward L. LaGory et al.
CELL REPORTS (2015)
PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress
Francisca Vazquez et al.
CANCER CELL (2013)
The Mitochondrial Chaperone TRAP1 Promotes Neoplastic Growth by Inhibiting Succinate Dehydrogenase
Marco Sciacovelli et al.
CELL METABOLISM (2013)
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
Joanna Kaplon et al.
NATURE (2013)
Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
Mohit Jain et al.
SCIENCE (2012)
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
Sophia Y. Lunt et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Metabolic Flux and the Regulation of Mammalian Cell Growth
Jason W. Locasale et al.
CELL METABOLISM (2011)
Peroxisome proliferator-activated receptor-γ coactivator 1-α (PGC1α) is a metabolic regulator of intestinal epithelial cell fate
Ilenia D'Errico et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
PGC-1 alpha in aging and anti-aging interventions
Rozalyn Anderson et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)
The bioenergetics of cancer: Is glycolysis the main ATP supplier in all tumor cells?
Rafael Moreno-Sanchez et al.
BIOFACTORS (2009)
Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells
Thomas McFate et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
PGC-1α induces apoptosis in human epithelial ovarian cancer cells through a PPARγ-dependent pathway
Yan Zhang et al.
CELL RESEARCH (2007)
Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer
T. E. Roche et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Growth yield homeostasis in respiring yeast is due to a strict mitochondrial content adjustment
Anne Devin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
JW Kim et al.
CELL METABOLISM (2006)
Competition of electrons to enter the respiratory chain -: A new regulatory mechanism of oxidative metabolism in Saccharomyces cerevisiae
O Bunoust et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The yeast cAMP protein kinase Tpk3p is involved in the regulation of mitochondrial enzymatic content during growth
C Chevtzoff et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2005)
Mitochondrial diseases: molecular mechanisms, clinical presentations and diagnosis investigations
K Aure et al.
ANNALES DE PATHOLOGIE (2005)
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
MA Selak et al.
CANCER CELL (2005)
The estrogen-related receptor α (ERRα) functions in PPARγ coactivator 1α (PGC-1α)-induced mitochondrial biogenesis
SN Schreiber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor γ coactivator-1α promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner
LK Russell et al.
CIRCULATION RESEARCH (2004)
Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells
R Rossignol et al.
CANCER RESEARCH (2004)
Contribution of the phosphorylable complex I in the growth phase-dependent respiration of C6 glioma cells in vitro
P Pasdois et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2003)
cAMP-induced modulation of the growth yield of Saccharomyces cerevisiae during respiratory and respiro-fermentative metabolism
L Dejean et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2002)
Network identification and flux quantification in the central metabolism of Saccharomyces cerevisiae under different conditions of glucose repression
AK Gombert et al.
JOURNAL OF BACTERIOLOGY (2001)
Peroxisome proliferator-activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis
JJ Lehman et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Starvation increases the amount of pyruvate dehydrogenase kinase in several mammalian tissues
PF Wu et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)