4.1 Article

Respiratory and heart rate dynamics during peripheral chemoreceptor deactivation compared to targeted sympathetic and sympathetic/ parasympathetic (co-)activation

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Summary: This review discusses the role of the carotid body in maintaining homeostasis through reflex ventilatory, cardiovascular, and humoral responses. It also examines the transduction mechanisms, synaptic mechanisms, and integrated reflex responses to CB activation in different physiological, pathological, or environmental challenges. The contribution of enhanced CB chemosensory discharge to autonomic and cardiorespiratory pathophysiology in various diseases is also highlighted.

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