4.6 Article

Low endogenous estradiol levels are associated with elevated risk of cardiovascular disease mortality in young and middle-aged men in the United States

Related references

Note: Only part of the references are listed.
Article Andrology

The association between testosterone, estradiol and their ratio and mortality among US men

Federico Belladelli et al.

Summary: The study suggests a significant association between low testosterone levels and male mortality, while abnormal estradiol levels showed no association with mortality. The testosterone to estradiol ratio was found to be related to cardiovascular disease-related mortality.

ANDROLOGIA (2021)

Article Clinical Neurology

Clinical impact of estradiol/testosterone ratio in patients with acute ischemic stroke

Jung-Won Choi et al.

Summary: The study found that the estradiol/testosterone ratio was significantly elevated among patients with acute ischemic stroke, and those with the highest ratio were more likely to have stroke.

BMC NEUROLOGY (2021)

Article Cardiac & Cardiovascular Systems

Heart Disease and Stroke Statistics-2021 Update A Report From the American Heart Association

Salim S. Virani et al.

Summary: The American Heart Association, in partnership with the National Institutes of Health, publishes annual statistics on heart disease, stroke, and cardiovascular risk factors, including the impact of health behaviors and factors on cardiovascular health. The Statistical Update covers a range of clinical heart and circulatory conditions, providing data on quality of care, procedures, and economic costs. It serves as a critical resource for various stakeholders seeking the best available data on these factors and conditions.

CIRCULATION (2021)

Article Endocrinology & Metabolism

Association of Genetically Predicted Serum Estradiol With Risk of Thromboembolism in Men: A Mendelian Randomization Study

Maria Nethander et al.

Summary: The study found that estradiol predicted by genetic variants in the CYP19A1 gene region was inversely associated with thromboembolism risk in men, while high testosterone levels were positively associated with increased risk of thromboembolism. In addition, estradiol was negatively associated with the risk of ischemic stroke, but not with the risk of myocardial infarction. The overall impact of sex steroids on thromboembolism in men may be influenced by the ratio between testosterone and estradiol determined by CYP19A1 activity.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2021)

Article Medicine, General & Internal

Trends in obesity and adiposity measures by race or ethnicity among adults in the United States 2011-18: population based study

Buyun Liu et al.

Summary: The study found an increasing trend in obesity and adiposity measures among US adults from 2011 to 2018, with disparities among racial or ethnic groups.

BMJ-BRITISH MEDICAL JOURNAL (2021)

Review Endocrinology & Metabolism

MECHANISMS IN ENDOCRINOLOGY Estradiol as a male hormone

Nicholas Russell et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2019)

Article Endocrinology & Metabolism

Age-Specific Serum Total and Free Estradiol Concentrations in Healthy Men in US Nationally Representative Samples

Susan Chadid et al.

JOURNAL OF THE ENDOCRINE SOCIETY (2019)

Review Physiology

ESTROGENS IN MALE PHYSIOLOGY

Paul S. Cooke et al.

PHYSIOLOGICAL REVIEWS (2017)

Article Public, Environmental & Occupational Health

Metabolic Syndrome Prevalence by Race/Ethnicity and Sex in the United States, National Health and Nutrition Examination Survey, 1988-2012

Justin Xavier Moore et al.

PREVENTING CHRONIC DISEASE (2017)

Review Cardiac & Cardiovascular Systems

Programming of cardiovascular disease across the life-course

Heather L. Blackmore et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)

Review Biochemistry & Molecular Biology

Free estradiol and sex hormone-binding globulin

William Rosner

STEROIDS (2015)

Article Endocrinology & Metabolism

Sex Hormone-Binding Globulin Gene Expression and Insulin Resistance

Stephen J. Winters et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)

Article Cardiac & Cardiovascular Systems

Endogenous Sex Hormones, Metabolic Syndrome, and Diabetes in Men and Women

Catherine Kim et al.

CURRENT CARDIOLOGY REPORTS (2014)

Article Medicine, General & Internal

Androgen activity, ischaemic heart disease and risk factors among men in NHANES III

C. Mary Schooling

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Endocrinology & Metabolism

Comparisons of Immunoassay and Mass Spectrometry Measurements of Serum Estradiol Levels and Their Influence on Clinical Association Studies in Men

Claes Ohlsson et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)

Article Peripheral Vascular Disease

Role of Endogenous Estrogen on the Incidence of Coronary Heart Disease in Men

Hongyun Zheng et al.

ANGIOLOGY (2012)

Article Andrology

Trends in sex hormone concentrations in US males: 1988-1991 to 1999-2004

S. J. Nyante et al.

INTERNATIONAL JOURNAL OF ANDROLOGY (2012)

Article Cardiac & Cardiovascular Systems

Estrogen Signaling and Cardiovascular Disease

Elizabeth Murphy

CIRCULATION RESEARCH (2011)

Article Endocrinology & Metabolism

Endogenous oestradiol but not testosterone is related to coronary artery disease in men

Emmanuela Quental Callou de Sa et al.

CLINICAL ENDOCRINOLOGY (2011)

Article Cardiac & Cardiovascular Systems

High Serum Testosterone Is Associated With Reduced Risk of Cardiovascular Events in Elderly Men The MrOS (Osteoporotic Fractures in Men) Study in Sweden

Claes Ohlsson et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2011)

Article Public, Environmental & Occupational Health

Sex Steroid Hormone Concentrations and Risk of Death in US Men

Andy Menke et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2010)

Article Endocrinology & Metabolism

Evidence for Geographical and Racial Variation in Serum Sex Steroid Levels in Older Men

Eric S. Orwoll et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)

Review Endocrinology & Metabolism

History of Aromatase: Saga of an Important Biological Mediator and Therapeutic Target

R. J. Santen et al.

ENDOCRINE REVIEWS (2009)

Article Endocrinology & Metabolism

Endogenous sex hormones and the prospective association with cardiovascular disease and mortality in men: the Tromso Study

Torkel Vikan et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2009)

Article Endocrinology & Metabolism

Low Serum Testosterone and Estradiol Predict Mortality in Elderly Men

Asa Tivesten et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)

Article Endocrinology & Metabolism

Serum estrogen, but not testosterone, levels differ between black and white men in a nationally representative sample of Americans

Sabine Rohrmann et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)

Review Medical Laboratory Technology

Metabolic syndrome and cardiovascular disease

Qing Qiao et al.

ANNALS OF CLINICAL BIOCHEMISTRY (2007)

Article Clinical Neurology

Serum estradiol and risk of stroke in elderly men

R. D. Abbott et al.

NEUROLOGY (2007)

Article Medicine, General & Internal

Endogenous sex hormones and cardiovascular disease incidence in men

Johan Arnlov et al.

ANNALS OF INTERNAL MEDICINE (2006)