Journal
ANNALS OF INTERNAL MEDICINE
Volume 175, Issue 9, Pages -Publisher
AMER COLL PHYSICIANS
DOI: 10.7326/AITC202209200
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- American College of Physicians
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Venous thromboembolism (VTE) is a common cardiovascular disorder that can be prevented through prophylaxis. Direct oral anticoagulants are effective and safe treatments with lower risk for bleeding. Postthrombotic syndrome is a common complication among patients with DVT and significantly impacts their quality of life.
Venous thromboembolism (VTE) is the third most common cardiovascular disorder, affecting up to 5% of the population. VTE commonly manifests as lower-extremity deep venous thrombosis (DVT) or pulmonary embolism. Half of these events are associated with a transient risk factor and may be preventable with prophylaxis. Direct oral anticoagulants are effective and safe and carry a lower risk for bleeding than vitamin K antagonists. Many patients with VTE will have a chronic disease requiring long-term anticoagulation. Postthrombotic syndrome affects 25% to 40% of patients with DVT and significantly impacts function and quality of life.
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