Breast Cancer Risk and Screening Mammography Frequency Among Multiethnic Women

Introduction: In 2009, the U.S. Preventive Services Task Force updated recommended mammogra-phy screening frequency from annual to biennial for average-risk women aged 50-74 years. The asso-ciation between estimated breast cancer risk and mammography screening frequency was evaluated. Methods: A single-center retrospective cohort study was conducted among racially/ethnically diverse women, aged 50-74 years, who underwent screening mammography from 2014 to 2018. Data on age, race/ethnicity, first-degree family history of breast cancer, previous benign breast biop-sies, and mammographic density were extracted from the electronic health record to calculate Breast Cancer Surveillance Consortium 5-year risk of invasive breast cancer, with a 5-year risk >= 1.67% defined as high risk. Multivariable analyses were conducted to determine the association between breast cancer risk factors and mammography screening frequency (annual versus biennial). Data were analyzed from 2020 to 2022. Results: Among 12,929 women with a mean age of 61 +/- 6.9 years, 82.7% underwent annual screen-ing mammography, and 30.7% met high-risk criteria for breast cancer. Hispanic women were more likely to screen annually than non-Hispanic Whites (85.0% vs 79.8%, respectively), despite fewer meeting high-risk criteria. In multivariable analyses adjusting for breast cancer risk factors, high-versus low/average-risk women (OR=1.17; 95% CI=1.04, 1.32) and Hispanic versus non-Hispanic White women (OR=1.46; 95% CI=1.29, 1.65) were more likely to undergo annual mammography. Conclusions: A majority of women continue to undergo annual screening mammography despite only a minority meeting high-risk criteria, and Hispanic women were more likely to screen annually despite lower overall breast cancer risk. Future studies should focus on the implementation of risk-stratified breast cancer screening strategies. Am J Prev Med 2023;64(1):51-60. (c) 2022 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

Automated summary

According to a retrospective cohort study, the majority of women continue to undergo annual mammography screening despite only a minority meeting high-risk criteria, with Hispanic women being more likely to screen annually than non-Hispanic Whites.