Electro-kinetically enhanced mass transport of charged macro-solutes through a microchannel with porous walls

Electrokinetics of the solute transport across the porous walls of micro channel is important from its practical application but less explored. Transport of the charged macro-solutes across perm-selective walls in a microchannel is investigated. The extended Nernst-Planck equation describes the charged macro-solutes distribution in the mass transfer boundary layer over the porous wall. The transverse electromigration of the charged macro-solute either augments or suppresses the concentration polarization and the permeation rate depending on the wall and solute surface potential (attractive or repelling). The wall potential is screened due to the electrical double layer interaction of the wall and charged solute. It is observed that the charged solute concentration over the channel wall enhances by two times in case of oppositely charged interactions (unlike solute and channel wall) compared to like charges. The findings of this study can facilitate understanding of electrokinetic based drug delivery and separation systems involving charged solutes.

Automated summary

This study investigates the transport of charged macro-solutes across perm-selective walls in a microchannel. The distribution of these solutes over the porous wall is described by the extended Nernst-Planck equation. The transverse electromigration of the charged solutes can either enhance or suppress concentration polarization and permeation rate, depending on the wall and solute surface potential. The findings of this study have implications for electrokinetic based drug delivery and separation systems involving charged solutes.