4.2 Article

Brachial artery blood flow by vascular ultrasound in education

Journal

ADVANCES IN PHYSIOLOGY EDUCATION
Volume 46, Issue 3, Pages 498-506

Publisher

AMER PHYSIOLOGICAL SOC
DOI: 10.1152/advan.00157.2021

Keywords

exercise; flow velocity; pulse wave Doppler ultrasound; reactive hyperemia

Funding

  1. Physiological Society David Jordan Teaching Award

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Ultrasound has extensive and increasing use in medical care and scientific research. The use of vascular ultrasound in physiology education is relatively neglected. This article reviews the techniques of vascular ultrasound and the physiological regulation of human limb blood flow, emphasizing the value of converting velocity measurement to volumetric flow.
There is extensive and increasing use of ultrasound in medical care and scientific research, so it is important that the technique, indication, and interpretation of ultrasound investigations are included in medical and biological education. Applications of ultrasound in medical care and education employ not only noninvasive imaging of structure but also the evaluation of organ function. Vascular ultrasound is one such application that has been hitherto relatively neglected in physiology education. The techniques of vascular ultrasound and the physiological regulation of human limb blood flow are reviewed to inform students and curriculum designers. Emphasis is placed on the value of converting velocity measurement by ultrasound to volumetric flow and on the mechanisms involved in rapidly changing flows with interventions. Live collection of real data by ultrasound can show macrovascular and microvascular features of vascular physiology. Macrovascular features include imaging and flow velocity profiles. Microvascular perfusion studies show conductance changes with interventions such as exercise and ischemia. Vascular ultrasound offers exciting opportunities for undergraduate research projects using human subjects. The literature is interesting and, though complex, offers excellent educational experience, with scope for the development of critical thinking and meaningful original research. NEW & NOTEWORTHY Ultrasound imaging has emergent prominence in clinical investigation and education. Vascular ultrasound also evaluates function. Simple methods are described that enable the application of basic ultrasound principles to the measurement of velocity and, importantly, to calculate absolute volumetric blood flow. These methods should be useful in undergraduate and graduate education, with application in clinical practice and research.

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