4.8 Review

Hollow Nanomaterials in Advanced Drug Delivery Systems: From Single- to Multiple Shells

Related references

Note: Only part of the references are listed.
Article Biotechnology & Applied Microbiology

Mitochondria-targeting multifunctional nanoplatform for cascade phototherapy and hypoxia-activated chemotherapy

Jie Lv et al.

Summary: By combining photodynamic therapy, photothermal therapy, and hypoxia-activated chemotherapy, this study developed a mitochondrial targeted nanoplatform that can synergistically treat tumors and maximize the therapeutic window.

JOURNAL OF NANOBIOTECHNOLOGY (2022)

Review Chemistry, Multidisciplinary

Stimuli-Responsive Nanoparticles for Controlled Drug Delivery in Synergistic Cancer Immunotherapy

Jin Zhang et al.

Summary: This review discusses the use of stimuli-responsive nanoparticles (srNPs) in cancer immunotherapy, highlighting their potential to enhance anti-tumor immune responses by combining with tumor microenvironment and external stimuli. The goal is to achieve synergistic immunotherapy and long-term immune memory to prevent tumor recurrence.

ADVANCED SCIENCE (2022)

Article Pharmacology & Pharmacy

Biomimetic platelet membrane-coated nanoparticles for targeted therapy

Huijie Han et al.

Summary: The development of cell membrane-modified biomimetic nanoparticles, specifically platelet membrane-coated nanoparticles, has shown great potential in the field of nanomedicine for targeted therapy. These nanoparticles can mimic the functions of primary cells and successfully deliver drugs to the targeted sites, enhancing therapeutic responses and reducing side effects. Platelet membrane-coated nanoparticles possess the characteristics of platelets, including immune system evasion and interaction with pathogens, making them an ideal drug delivery system.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2022)

Review Chemistry, Physical

Hollow structures as drug carriers: Recognition, response, and release

Decai Zhao et al.

Summary: Hollow structures show great potential in drug delivery due to their unique features such as high surface-to-volume ratio, low density, large cavities, and hierarchical pores. They are widely used in targeting recognition, smart response, and drug release, with advantages including large loading capacity, controllable release, and flexibility in application. Hollow multishelled structures are particularly promising for their unique loading and releasing properties induced by multiple physical barriers and chemical interactions.

NANO RESEARCH (2022)

Article Chemistry, Multidisciplinary

Recent Advancements in Mitochondria-Targeted Nanoparticle Drug Delivery for Cancer Therapy

Jiangsheng Xu et al.

Summary: Mitochondria are critical organelles for producing energy in cells and can be targeted for cancer therapy. Mitochondria-targeting nanotechnologies have shown high efficacy for cancer treatment both in vitro and in vivo, and can be intelligently designed based on the characteristics of the tumor microenvironment.

NANOMATERIALS (2022)

Review Pharmacology & Pharmacy

Nanocarrier Drug Delivery Systems: Characterization, Limitations, Future Perspectives and Implementation of Artificial Intelligence

Samar Zuhair Alshawwa et al.

Summary: There is an increasing demand for the development of nanocarriers that can target multiple diseases with a broad range of properties. Nanocarriers, due to their tiny size, large surface area, and feasible targetability, have optimized efficacy, decreased side effects, and improved stability compared to conventional drug dosage forms. Various types of nanocarriers have been synthesized for drug delivery, and characterization techniques have been proposed and used to predict the behavior of nanocarriers in vitro and in vivo. However, challenges in safety, regulation, and manufacturing hinder the translation of nanocarriers from the laboratory to the clinic.

PHARMACEUTICS (2022)

Editorial Material Pharmacology & Pharmacy

Delivery Systems of Plasmid DNA and Messenger RNA for Advanced Therapies

Satoshi Uchida

PHARMACEUTICS (2022)

Article Multidisciplinary Sciences

An effective nano drug delivery and combination therapy for the treatment of Tuberculosis

Mojgan Sheikhpour et al.

Summary: Drug resistance in tuberculosis is a serious threat, and new drug combinations and targeted drug delivery methods are needed. Fluoxetine, an antidepressant, has potential in treating bacterial infections. The conjugated nanofluid of isoniazid and fluoxetine has shown significant effects against tuberculosis strains and can reduce drug dosage.

SCIENTIFIC REPORTS (2022)

Review Biochemistry & Molecular Biology

RNA therapy: rich history, various applications and unlimited future prospects

Young-Kook Kim

Summary: RNA therapy utilizes RNA molecules for the treatment or prevention of diseases, offering a potential solution for diseases that do not respond to conventional drug types. Recent success in developing messenger RNA-based vaccines for COVID-19 has sparked renewed interest in RNA therapy. Despite challenges in drug delivery, RNA therapy shows great promise for developing innovative therapeutic agents in the future.

EXPERIMENTAL AND MOLECULAR MEDICINE (2022)

Review Nanoscience & Nanotechnology

Protein-Based Encapsulation Strategies: Toward Micro- and Nanoscale Carriers with Increased Functionality

Ricardo Ramos et al.

Summary: This review provides a comprehensive overview of micro- and nanocapsules predominantly made of proteins and peptides, detailing their different fabrication techniques and possible applications. It emphasizes the capability of proteins and peptides to assemble into capsule structures and the physical nature of the capsule core.

SMALL SCIENCE (2022)

Review Biochemistry & Molecular Biology

Monoclonal Antibodies Carried in Drug Delivery Nanosystems as a Strategy for Cancer Treatment

Amanda Leticia Polli Silvestre et al.

Summary: Monoclonal antibodies encapsulated in nanosystems show great potential for cancer treatment by overcoming challenges faced by traditional monoclonal antibodies and improving therapeutic efficacy.

CURRENT MEDICINAL CHEMISTRY (2021)

Article Nanoscience & Nanotechnology

One-Pot Fabrication of Hollow Porphyrinic MOF Nanoparticles with Ultrahigh Drug Loading toward Controlled Delivery and Synergistic Cancer Therapy

Xin Sun et al.

Summary: Hollow porphyrinic metal-organic framework nanoparticles with a mesoporous spherical shell were fabricated as drug carriers, showing ultrahigh drug-loading capacity and superior photodynamic therapy efficacy.

ACS APPLIED MATERIALS & INTERFACES (2021)

Article Biochemistry & Molecular Biology

Efficient Synthesis of Folate-Conjugated Hollow Polymeric Capsules for Accurate Drug Delivery to Cancer Cells

Wenliang Song et al.

Summary: This study presents an efficient and systematic approach to synthesize bioapplicable porous hollow polymeric capsules, offering potential applications in drug delivery. By converting hydroxyl groups on the surface to carboxyl groups, biomolecules can be covalently decorated on the organic capsules. The research results show that these organic capsules have potential applications in drug encapsulation efficiency and release.

BIOMACROMOLECULES (2021)

Article Engineering, Biomedical

Advances and perspectives in carrier-free nanodrugs for cancer chemo-monotherapy and combination therapy

Li Huang et al.

Summary: Carrier-free nanodrugs, completely formulated with one or more drugs, have shown great potential in cancer therapy by improving pharmacodynamics/pharmacokinetics, reducing toxicity, and increasing drug loading. Utilizing different preparation strategies, these nanodrugs have demonstrated advantages in various therapeutic modalities, which may pave the way for effective treatments in the future.

BIOMATERIALS (2021)

Review Nanoscience & Nanotechnology

Advances in Multiple Stimuli-Responsive Drug-Delivery Systems for Cancer Therapy

Ruixin Jia et al.

Summary: Nanomedicines offer unique advantages in tumor therapy, but traditional nanomedicines are hindered by complex physiological fluids and tumor microenvironments. Stimuli-responsive drug-delivery systems have emerged as a promising tool to overcome these barriers and deliver therapeutic agents to target sites effectively.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Editorial Material Chemistry, Multidisciplinary

Engineering biomimetic epigenetic nanoinducer improves cancer immunotherapy

Yuliang Zhao

SCIENCE CHINA-CHEMISTRY (2021)

Article Multidisciplinary Sciences

Interfacial engineering of Bi2S3/Ti3C2Tx MXene based on work function for rapid photo-excited bacteria-killing

Jianfang Li et al.

Summary: An interfacial Schottky junction of Bi2S3/Ti3C2Tx has been designed to improve photocatalytic activity by increasing local electron density and inhibiting electron backflow, effectively eradicating Staphylococcus aureus and Escherichia coli.

NATURE COMMUNICATIONS (2021)

Article Nanoscience & Nanotechnology

Core-shell Fe3O4@ZnO nanoparticles for magnetic hyperthermia and bio-imaging applications

Jagriti Gupta et al.

Summary: Combining magnetic Fe3O4@ZnO core-shell nanoparticles for cancer treatment has shown potential in non-invasive imaging and therapy, with good performance in magnetic hyperthermia and fluorescent cell imaging capabilities.

AIP ADVANCES (2021)

Review Pharmacology & Pharmacy

Metal-organic frameworks for advanced drug delivery

Siyu He et al.

Summary: Metal-organic frameworks (MOFs) are highly porous, crystalline materials composed of organic ligands and metal ions/metal clusters. They are increasingly popular in drug delivery due to their tunable porosity, chemical composition, and surface functionalization capabilities. Despite their potential in biomedical applications, challenges such as biostability and biosafety need to be addressed in the development of MOFs for drug delivery systems.

ACTA PHARMACEUTICA SINICA B (2021)

Review Biochemistry & Molecular Biology

Exploiting a New Approach to Destroy the Barrier of Tumor Microenvironment: Nano-Architecture Delivery Systems

Yanting Sun et al.

Summary: Recent research indicates that the tumor microenvironment (TME) plays a crucial role in tumor occurrence, proliferation, and metastasis. Researchers are increasingly focusing on targeting TME to prevent tumor development. Stimulus-responsive intelligent nanostructures designed based on TME have attracted attention in anti-tumor drug delivery systems.

MOLECULES (2021)

Article Medicine, General & Internal

Vaccine Breakthrough Infections with SARS-CoV-2 Variants

Ezgi Hacisuleyman et al.

Summary: Despite evidence of vaccine efficacy, two fully vaccinated individuals developed mild symptoms of Covid-19 and were infected with variants of SARS-CoV-2. Sequencing of the virus isolates revealed novel mutations, highlighting the potential risk of illness post-vaccination and subsequent infection with variant virus. Efforts to prevent, diagnose, and characterize variants in vaccinated individuals are crucial.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Article Multidisciplinary Sciences

Normal tissue architecture determines the evolutionary course of cancer

Jeffrey West et al.

Summary: This study utilized mathematical modeling to investigate the competition for space in cancer evolution in spatially constrained tissues, revealing the significant impact of spatial constraints on tumor evolution. It explored how genetic heterogeneity and driver mutations within tumors change over time, highlighting the role of tissue structure in influencing the mode of cancer evolution.

NATURE COMMUNICATIONS (2021)

Review Polymer Science

Recent Advancements in Polymer/Liposome Assembly for Drug Delivery: From Surface Modifications to Hybrid Vesicles

Vincenzo De Leo et al.

Summary: This article discusses the use of polymer/liposome assembly in drug delivery to improve carrier performance, overcome limitations of vesicles, enhance drug stability and bioavailability, while reducing side effects.

POLYMERS (2021)

Article Chemistry, Multidisciplinary

Specific Endothelial Cells Govern Nanoparticle Entry into Solid Tumors

Benjamin R. Kingston et al.

Summary: A subset of tumor endothelial cells, named N-TECs, has been discovered to facilitate the transport of nanoparticles into solid tumors. Only 21% of tumor endothelial cells are involved in this process, with N-TECs showing increased expression of genes related to nanoparticle transport and vessel permeability compared to other cells. N-TECs act as gatekeepers determining the entry point, distribution, cell accessibility, and number of nanoparticles entering the tumor microenvironment.

ACS NANO (2021)

Review Pharmacology & Pharmacy

Liposome composition in drug delivery design, synthesis, characterization, and clinical application

Danielle E. Large et al.

Summary: Liposomal drug delivery is a highly adaptable therapeutic platform for treating a wide range of diseases. The molecular diversity in liposome composition enables drug delivery with unique physiological functions, such as pH response and reduced systemic toxicity.

ADVANCED DRUG DELIVERY REVIEWS (2021)

Review Nanoscience & Nanotechnology

The current landscape of nucleic acid therapeutics

Jayesh A. Kulkarni et al.

Summary: The increasing number of approved nucleic acid therapeutics demonstrates their potential for long-lasting or curative effects by targeting genetic blueprints; however, their clinical translation relies on advances in delivery technologies. Four platform technologies, including antisense oligonucleotides, small interfering RNA conjugates, lipid nanoparticles, and adeno-associated virus vectors, have enabled the clinical translation of nucleic acid therapeutics, leading to the approval of cutting-edge genetic drugs.

NATURE NANOTECHNOLOGY (2021)

Review Pharmacology & Pharmacy

Cationic Liposomes as Vectors for Nucleic Acid and Hydrophobic Drug Therapeutics

Kai K. Ewert et al.

Summary: Cationic liposomes have been explored as effective carriers for various therapeutics, particularly nucleic acids, with recent milestones in the approval of siRNA therapeutic patisiran and mRNA vaccines against COVID-19. Understanding the structure of these carriers and their interactions with cell membranes is crucial for optimizing their use in medical applications, including targeted delivery of nucleic acids in vivo.

PHARMACEUTICS (2021)

Review Chemistry, Physical

Small Structures Bring Big Things: Performance Control of Hollow Multishelled Structures

Li Wang et al.

Summary: Research on hollow multishelled structures (HoMSs) in the past decade has enriched their chemical compositions and geometric structures through advanced synthetic methods and characterization technologies. The control of HoMSs' compositional and structural characteristics can optimize their performance in mass transport, storage, and release.

SMALL STRUCTURES (2021)

Article Nanoscience & Nanotechnology

Systematic Analysis of Composition, Interfacial Performance and Effects of Pulmonary Surfactant Preparations on Cellular Uptake and Cytotoxicity of Aerosolized Nanomaterials

Benedikt Huck et al.

Summary: By investigating the interactions between nanoparticles and pulmonary surfactant, researchers found that surfactant preparations with high interfacial activity and distinctive composition can reduce the toxicity of aerosolized particles and help decrease the aggregation of aerosolized particles. These findings help identify key requirements when studying interactions of nanomaterials with the pulmonary air-blood barrier in vitro.

SMALL SCIENCE (2021)

Article Nanoscience & Nanotechnology

High-Efficient and Dosage-Controllable Intracellular Cargo Delivery through Electrochemical Metal-Organic Hybrid Nanogates

Bowen Zhang et al.

Summary: The combination of hollow nanostructures and electroporation allows for the delivery of versatile cargos into adhesive cells at low voltages, utilizing a metal-organic hybrid nanotube stamp. This approach improves cell viability and demonstrates efficient transport of small and large molecules into the cells.

SMALL SCIENCE (2021)

Review Materials Science, Biomaterials

Hollow iron oxide nanomaterials: synthesis, functionalization, and biomedical applications

Ruixue Wei et al.

Summary: Hollow iron oxide nanoparticles are a promising class of nanostructures with low toxicity, good biocompatibility, and intrinsic magnetic properties, making them attractive in biomedical applications. Various strategies for synthesis, surface functionalization, and biomedical applications of hollow iron oxide nanoparticles have been reviewed, highlighting their potential in magnetic resonance imaging, drug delivery, and cancer therapy. Prospects for further development of hollow iron oxide nanoparticles have also been discussed.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Review Nanoscience & Nanotechnology

Functional Nucleic-Acid-Decorated Spherical Nanoparticles: Preparation Strategies and Current Applications in Cancer Therapy

Min Zhu et al.

Summary: Functional nucleic acid-decorated spherical nanoparticles (FSNPs) show unique capabilities for cancer therapy, such as resistance to nuclease degradation and ability to cross the blood-brain barrier. They can be used for tumor-targeted drug delivery, controlled drug release, overcoming physiological or pathological barriers, as well as reversing resistance to chemotherapy and activating anti-tumor immune responses.

SMALL SCIENCE (2021)

Review Nanoscience & Nanotechnology

Nanoarchitectonics Revolution and Evolution: From Small Science to Big Technology

Katsuhiko Ariga

Summary: With advancements in material synthesis, the importance of structural regulation has been realized, leading to the emergence of a novel concept known as nanoarchitectonics that combines nanotechnology with other scientific disciplines to create functional material systems using contributions from small objects and nano-units. This approach allows for the construction of unusual functional systems, such as brain-like information processing and probe-tip-mediated organic reactions, by utilizing nano-units in conjunction with various research fields.

SMALL SCIENCE (2021)

Article Chemistry, Multidisciplinary

Bile duct ligation enhances AZT CNS toxicity partly by impairing the expression and function of BCRP in rat brain

Yuan-yuan Qin et al.

ACTA PHARMACOLOGICA SINICA (2020)

Review Pharmacology & Pharmacy

Protein drug delivery: current dosage form profile and formulation strategies

Danilo Costa Geraldes et al.

JOURNAL OF DRUG TARGETING (2020)

Article Chemistry, Applied

Polymer-mesoporous silica composites for drug release systems

Agnieszka Kierys et al.

MICROPOROUS AND MESOPOROUS MATERIALS (2020)

Review Chemistry, Multidisciplinary

Interfacial Assembly of Mesoporous Silica-Based Optical Heterostructures for Sensing Applications

Meng Gao et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Review Chemistry, Multidisciplinary

Fluorescent Reporters for Drug Delivery Monitoring

Leonid Patsenker et al.

ISRAEL JOURNAL OF CHEMISTRY (2020)

Article Nanoscience & Nanotechnology

Biomimetic nanovesicles made from iPS cell-derived mesenchymal stem cells for targeted therapy of triple-negative breast cancer

Qingguo Zhao et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2020)

Article Multidisciplinary Sciences

Unexpected intracellular biodegradation and recrystallization of gold nanoparticles

Alice Balfourier et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Materials Science, Multidisciplinary

Multifunctional nanoplatforms for subcellular delivery of drugs in cancer therapy

Xing Guo et al.

PROGRESS IN MATERIALS SCIENCE (2020)

Review Pharmacology & Pharmacy

Delivery strategies for macromolecular drugs in cancer therapy

Qin Guo et al.

ACTA PHARMACEUTICA SINICA B (2020)

Review Chemistry, Multidisciplinary

Current Advances of Hollow Capsules as Controlled Drug Delivery Systems

Huy Quang Tran et al.

CHEMISTRYSELECT (2020)

Article Chemistry, Inorganic & Nuclear

Temperature/pH/magnetic triple sensitive nanogel for doxorubicin anticancer drug delivery

Marziyeh Hayati et al.

INORGANIC AND NANO-METAL CHEMISTRY (2020)

Review Biotechnology & Applied Microbiology

Ultrashort Peptide Self-Assembly: Front-Runners to Transport Drug and Gene Cargos

Seema Gupta et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

Article Chemistry, Applied

Recent advances in surface engineering of porous silicon nanomaterials for biomedical applications

Yuna Jung et al.

MICROPOROUS AND MESOPOROUS MATERIALS (2020)

Article Biotechnology & Applied Microbiology

Functionalized silk spheres selectively and effectively deliver a cytotoxic drug to targeted cancer cells in vivo

Anna Florczak et al.

JOURNAL OF NANOBIOTECHNOLOGY (2020)

Review Pharmacology & Pharmacy

Celastrol: A Review of Useful Strategies Overcoming its Limitation in Anticancer Application

Jinfeng Shi et al.

FRONTIERS IN PHARMACOLOGY (2020)

Review Chemistry, Multidisciplinary

Nanoplatform-based cascade engineering for cancer therapy

Jiajie Chen et al.

CHEMICAL SOCIETY REVIEWS (2020)

Review Engineering, Biomedical

Recent advances in polymeric drug delivery systems

Yong Kiel Sung et al.

BIOMATERIALS RESEARCH (2020)

Review Nanoscience & Nanotechnology

Strategies to improve tumor penetration of nanomedicines through nanoparticle design

Ya-Ru Zhang et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2019)

Review Pharmacology & Pharmacy

Adapting liposomes for oral drug delivery

Haisheng He et al.

ACTA PHARMACEUTICA SINICA B (2019)

Review Chemistry, Multidisciplinary

Recent Advances in Subcellular Targeted Cancer Therapy Based on Functional Materials

Wei-Hai Chen et al.

ADVANCED MATERIALS (2019)

Article Nanoscience & Nanotechnology

Dual Stimuli-Triggered Nanogels in Response to Temperature and pH Changes for Controlled Drug Release

Yun Kyoung Kim et al.

NANOSCALE RESEARCH LETTERS (2019)

Article Chemistry, Multidisciplinary

Preparation of Targeted Lignin-Based Hollow Nanoparticles for the Delivery of Doxorubicin

Yu Zhou et al.

NANOMATERIALS (2019)

Article Chemistry, Multidisciplinary

A Biomimetic Coordination Nanoplatform for Controlled Encapsulation and Delivery of Drug-Gene Combinations

Bei Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Physical

Magnetic liposome design for drug release systems responsive to super-low frequency alternating current magnetic field (AC MF)

Kseniya Yu Vlasova et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2019)

Review Pharmacology & Pharmacy

An overview of active and passive targeting strategies to improve the nanocarriers efficiency to tumour sites

Mohamed F. Attia et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2019)

Review Chemistry, Multidisciplinary

Hollow Multishelled Structures for Promising Applications: Understanding the Structure-Performance Correlation

Jiangyan Wang et al.

ACCOUNTS OF CHEMICAL RESEARCH (2019)

Review Pharmacology & Pharmacy

Subchronic and chronic toxicity evaluation of inorganic nanoparticles for delivery applications

Raziye Mohammadpour et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

Review Medicine, Research & Experimental

A Look at Receptor-Ligand Pairs for Active-Targeting Drug Delivery from Crystallographic and Molecular Dynamics Perspectives

Gergana Gocheva et al.

MOLECULAR PHARMACEUTICS (2019)

Article Multidisciplinary Sciences

Enhancing humoral immunity via sustained-release implantable microneedle patch vaccination

Archana V. Boopathy et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Biochemistry & Molecular Biology

Recent Advancements in Non-Invasive Formulations for Protein Drug Delivery

Rajiv Bajracharya et al.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2019)

Article Nanoscience & Nanotechnology

Doxorubicin/Cisplatin-Loaded Superparamagnetic Nanoparticles As A Stimuli-Responsive Co-Delivery System For Chemo-Photothermal Therapy

Mona Khafaji et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

Article Chemistry, Multidisciplinary

Curcumin Releasing Eggshell Derived Carbonated Apatite Nanocarriers for Combined Anti-Cancer, Anti-Inflammatory and Bone Regenerative Therapy

Anish H. Verma et al.

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY (2019)

Review Pharmacology & Pharmacy

Design strategies for shape-controlled magnetic iron oxide nanoparticles

Alejandro G. Roca et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

Article Chemistry, Multidisciplinary

Mesoporous Organosilica Hollow Nanoparticles: Synthesis and Applications

Zhaogang Teng et al.

ADVANCED MATERIALS (2019)

Article Chemistry, Multidisciplinary

Sequential Templating Approach: A Groundbreaking Strategy to Create Hollow Multishelled Structures

Dan Mao et al.

ADVANCED MATERIALS (2019)

Article Engineering, Chemical

Design and characterization of a multi-layered polymeric drug delivery vehicle

Kei Xian Tan et al.

CANADIAN JOURNAL OF CHEMICAL ENGINEERING (2019)

Article Biotechnology & Applied Microbiology

Predicting the mutations generated by repair of Cas9-induced double-strand breaks

Felicity Allen et al.

NATURE BIOTECHNOLOGY (2019)

Article Engineering, Biomedical

A Review of Controlled Drug Delivery Systems Based on Cells and Cell Membranes

Seyed Mohammad Zargar et al.

JOURNAL OF MEDICAL SIGNALS & SENSORS (2019)

Review Materials Science, Biomaterials

Controlled synthesis and assembly of ultra-small nanoclusters for biomedical applications

Qiyue Wang et al.

BIOMATERIALS SCIENCE (2019)

Review Chemistry, Multidisciplinary

The role of hollow magnetic nanoparticles in drug delivery

Ghodsi Mohammadi Ziarani et al.

RSC ADVANCES (2019)

Review Engineering, Biomedical

Therapeutic efficacy of nanoparticles and routes of administration

Dhrisya Chenthamara et al.

BIOMATERIALS RESEARCH (2019)

Article Nanoscience & Nanotechnology

Organelle-Targeting Gold Nanorods for Macromolecular Profiling of Subcellular Organelles and Enhanced Cancer Cell Killing

Yanting Shen et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

Review Biotechnology & Applied Microbiology

Bacterial components as naturally inspired nano-carriers for drug/gene delivery and immunization: Set the bugs to work?

Fatemeh Farjadian et al.

BIOTECHNOLOGY ADVANCES (2018)

Article Materials Science, Multidisciplinary

Dual-pH-sensitive mesoporous silica nanoparticle-based drug delivery system for tumor-triggered intracellular drug release

Hui Chen et al.

JOURNAL OF MATERIALS SCIENCE (2018)

Article Chemistry, Multidisciplinary

Biomarker Displacement Activation: A General Host-Guest Strategy for Targeted Phototheranostics in Vivo

Jie Gao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Chemistry, Multidisciplinary

Acid-Resistant Mesoporous Metal-Organic Framework toward Oral Insulin Delivery: Protein Encapsulation, Protection, and Release

Yijing Chen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Multidisciplinary Sciences

Novel concept of the smart NIR-light-controlled drug release of black phosphorus nanostructure for cancer therapy

Meng Qiu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Materials Science, Biomaterials

Multifunctional bacterial imaging and therapy systems

Shuai Chen et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

Review Pharmacology & Pharmacy

Leukocyte-derived biomimetic nanoparticulate drug delivery systems for cancer therapy

Yukun Huang et al.

ACTA PHARMACEUTICA SINICA B (2018)

Article Engineering, Biomedical

A degradable triple temperature-, pH-, and redox-responsive drug system for cancer chemotherapy

Bing Yu et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2018)

Review Chemistry, Physical

Cell-based drug delivery systems for biomedical applications

Teng Li et al.

NANO RESEARCH (2018)

Review Cell & Tissue Engineering

Concise Review: Mesenchymal Stem Cell-Based Drug Delivery: The Good, the Bad, the Ugly, and the Promise

Timothy E. G. Krueger et al.

STEM CELLS TRANSLATIONAL MEDICINE (2018)

Review Pharmacology & Pharmacy

Advances of blood cell-based drug delivery systems

Yanan Sun et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)

Review Chemistry, Multidisciplinary

Spatio-temporal control strategy of drug delivery systems based nano structures

Nahla Rahoui et al.

JOURNAL OF CONTROLLED RELEASE (2017)

Article Microbiology

Regulation of Class A β-Lactamase CzoA by CzoR and IscR in Comamonas testosteroni S44

Weiping Zhuang et al.

FRONTIERS IN MICROBIOLOGY (2017)

Review Chemistry, Multidisciplinary

Mesoporous Silica Nanoparticles as Drug Delivery Vehicles in Cancer

Anna Watermann et al.

NANOMATERIALS (2017)

Review Biochemical Research Methods

Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?

Yuko Nakamura et al.

BIOCONJUGATE CHEMISTRY (2016)

Review Biochemistry & Molecular Biology

The recognition of ubiquitinated proteins by the proteasome

Guinevere L. Grice et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2016)

Article Chemistry, Multidisciplinary

Outstanding drug loading capacity by water stable microporous MOF: a potential drug carrier

Partha Pratim Bag et al.

CHEMICAL COMMUNICATIONS (2016)

Review Chemistry, Multidisciplinary

Blood-brain barrier shuttle peptides: an emerging paradigm for brain delivery

Benjami Oller-Salvia et al.

CHEMICAL SOCIETY REVIEWS (2016)

Article Chemistry, Multidisciplinary

Nanotechnology for protein delivery: Overview and perspectives

Mikyung Yu et al.

JOURNAL OF CONTROLLED RELEASE (2016)

Article Chemistry, Multidisciplinary

Fabrication of hollow porous PLGA microspheres using sucrose for controlled dual delivery of dexamethasone and BMP2

Young-Bock Shim et al.

JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY (2016)

Article Chemistry, Applied

Dual-templating synthesis of multi-shelled mesoporous silica nanoparticles as catalyst and drug carrier

Lu Wu et al.

MICROPOROUS AND MESOPOROUS MATERIALS (2016)

Article Chemistry, Multidisciplinary

Stimuli-free programmable drug release for combination chemo-therapy

Li Fan et al.

NANOSCALE (2016)

Review Medicine, Research & Experimental

The Smart Drug Delivery System and Its Clinical Potential

Dong Liu et al.

THERANOSTICS (2016)

Article Materials Science, Biomaterials

Role of Tetra Amino Acid Motif Properties on the Function of Protease-Activatable Viral Vectors

T. M. Robinson et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2016)

Article Materials Science, Biomaterials

Role of Tetra Amino Acid Motif Properties on the Function of Protease-Activatable Viral Vectors

T. M. Robinson et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2016)

Review Nanoscience & Nanotechnology

Mesoporous materials for energy conversion and storage devices

Wei Li et al.

NATURE REVIEWS MATERIALS (2016)

Article Nanoscience & Nanotechnology

PLGA-Mesoporous Silicon Microspheres for the in Vivo Controlled Temporospatial Delivery of Proteins

Silvia Minardi et al.

ACS APPLIED MATERIALS & INTERFACES (2015)

Review Chemistry, Multidisciplinary

In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles

Hamed Arami et al.

CHEMICAL SOCIETY REVIEWS (2015)

Review Chemistry, Medicinal

Nucleic acid-based drugs against emerging zoonotic viruses

Jonathan P. Wong

FUTURE MEDICINAL CHEMISTRY (2015)

Review Nanoscience & Nanotechnology

Therapeutic Potential of Inorganic Nanoparticles for the Delivery of Monoclonal Antibodies

Christopher T. Turner et al.

JOURNAL OF NANOMATERIALS (2015)

Article Chemistry, Multidisciplinary

A Facile Multi-interface Transformation Approach to Monodisperse Multiple-Shelled Periodic Mesoporous Organosilica Hollow Spheres

Zhaogang Teng et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Article Engineering, Biomedical

Carbohydrate-Conjugated Hollow Oblate Mesoporous Silica Nanoparticles as Nanoantibiotics to Target Mycobacteria

Nanjing Hao et al.

ADVANCED HEALTHCARE MATERIALS (2015)

Review Pharmacology & Pharmacy

Advances and Challenges of Liposome Assisted Drug Delivery

Lisa Sercombe et al.

FRONTIERS IN PHARMACOLOGY (2015)

Article Chemistry, Multidisciplinary

Shaping Nanoparticles with Hydrophilic Compositions and Hydrophobic Properties as Nanocarriers for Antibiotic Delivery

Yusilawati Ahmad Nor et al.

ACS CENTRAL SCIENCE (2015)

Review Oncology

Cancer active targeting by nanoparticles: a comprehensive review of literature

Remon Bazak et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2015)

Review Chemistry, Medicinal

Nano-enabled delivery systems across the blood-brain barrier

Seung Rim Hwang et al.

ARCHIVES OF PHARMACAL RESEARCH (2014)

Review Chemistry, Multidisciplinary

Emerging micro-and nanotechnology based synthetic approaches for insulin delivery

Ran Mo et al.

CHEMICAL SOCIETY REVIEWS (2014)

Review Biochemistry & Molecular Biology

Nanoparticles for gene delivery: therapeutic and toxic effects

Young Suk Choi et al.

MOLECULAR & CELLULAR TOXICOLOGY (2014)

Article Chemistry, Multidisciplinary

Enzyme-responsive nanomaterials for controlled drug delivery

Quanyin Hu et al.

NANOSCALE (2014)

Article Chemistry, Analytical

Fluorescent and colorimetric detection of pH by a rhodamine-based probe

Lijuan Liu et al.

SENSORS AND ACTUATORS B-CHEMICAL (2014)

Review Nanoscience & Nanotechnology

Nanoparticle approaches against bacterial infections

Weiwei Gao et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2014)

Review Multidisciplinary Sciences

Selective chemical protein modification

Christopher D. Spicer et al.

NATURE COMMUNICATIONS (2014)

Article Multidisciplinary Sciences

Direct cellular delivery of human proteasomes to delay tau aggregation

Dong Hoon Han et al.

NATURE COMMUNICATIONS (2014)

Article Multidisciplinary Sciences

Margination of micro- and nano-particles in blood flow and its effect on drug delivery

Kathrin Mueller et al.

SCIENTIFIC REPORTS (2014)

Review Pharmacology & Pharmacy

Liposomal drug delivery systems: From concept to clinical applications

Theresa M. Allen et al.

ADVANCED DRUG DELIVERY REVIEWS (2013)

Article Chemistry, Multidisciplinary

Redox- and Temperature-Controlled Drug Release from Hollow Mesoporous Silica Nanoparticles

Yunfeng Jiao et al.

CHEMISTRY-A EUROPEAN JOURNAL (2013)

Article Chemistry, Multidisciplinary

Integrated Hollow Mesoporous Silica Nanoparticles for Target Drug/siRNA Co-Delivery

Xing Ma et al.

CHEMISTRY-A EUROPEAN JOURNAL (2013)

Review Chemistry, Physical

Stimuli-responsive nanocarriers for drug delivery

Simona Mura et al.

NATURE MATERIALS (2013)

Review Chemistry, Multidisciplinary

Polymeric multilayer capsules for drug delivery

Stefaan De Koker et al.

CHEMICAL SOCIETY REVIEWS (2012)

Meeting Abstract Chemistry, Multidisciplinary

Delivery of functional proteins to brain tumor using MRI-monitored, magnetically-targeted nanoparticles

B. Chertok et al.

JOURNAL OF CONTROLLED RELEASE (2008)

Article Chemistry, Applied

Storage and release of ibuprofen drug molecules in hollow mesoporous silica spheres with modified pore surface

YF Zhu et al.

MICROPOROUS AND MESOPOROUS MATERIALS (2005)