4.8 Article

An Injectable Rapid-Adhesion and Anti-Swelling Adhesive Hydrogel for Hemostasis and Wound Sealing

Related references

Note: Only part of the references are listed.
Review Chemistry, Multidisciplinary

Supramolecular Adhesive Hydrogels for Tissue Engineering Applications

Yue Zhao et al.

Summary: Tissue engineering offers a promising approach for treating organ or tissue loss, with supramolecular adhesive hydrogels showing great potential due to their unique properties. This review comprehensively summarizes the design principles and applications of adhesive hydrogels, highlighting their efficacy in various tissue repair processes.

CHEMICAL REVIEWS (2022)

Article Engineering, Biomedical

A strain-programmed patch for the healing of diabetic wounds

Georgios Theocharidis et al.

Summary: A polymer patch that adheres to diabetic wounds and contracts in a pre-programmed manner has shown to promote wound closure and re-epithelialization in mouse and human skin, in mini-pigs and in humanized mice. The patch consists of a dried adhesive layer of crosslinked polymer networks and a pre-stretched hydrophilic elastomer backing, utilizing a hydration-based shape-memory mechanism. In preclinical trials, the patch enhanced the healing of diabetic wounds by promoting faster re-epithelialization and angiogenesis, and enriching the fibroblast populations with a pro-regenerative phenotype.

NATURE BIOMEDICAL ENGINEERING (2022)

Article Engineering, Biomedical

Cohesion mechanisms for bioadhesives

Yazhong Bu et al.

Summary: Bioadhesives are transforming clinical practices by their strength and cohesion mechanisms, which are crucial for their overall function and application. While there is extensive research on adhesion mechanisms, cohesion mechanisms have received less attention.

BIOACTIVE MATERIALS (2022)

Review Chemistry, Multidisciplinary

Polymeric Tissue Adhesives

Sungmin Nam et al.

Summary: Polymeric tissue adhesives are versatile materials widely used in wound management, offering relative ease of use and rapid application while also acting as hemostats. Despite facing challenges, advancements in tissue adhesives may provide new possibilities for wound care.

CHEMICAL REVIEWS (2021)

Article Chemistry, Multidisciplinary

Genetically Engineered Polypeptide Adhesive Coacervates for Surgical Applications

Jing Sun et al.

Summary: A new type of non-swelling protein adhesive has been developed for underwater and in vivo applications, utilizing electrostatic complexation between supercharged polypeptides and oppositely charged surfactants to form ultra-strong adhesive coacervates. Its adhesion capability surpasses commercial products and other protein-based adhesives in both ambient and underwater conditions, as demonstrated by ex vivo and in vivo experiments showing persistent adhesive performance and outstanding wound sealing and healing behaviors.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Review Materials Science, Biomaterials

Advances in versatile anti-swelling polymer hydrogels

Yiwei Zhan et al.

Summary: Traditional hydrogels tend to swell, leading to mechanical property deterioration and undesired pressure on surrounding tissues when applied. In contrast, anti-swelling hydrogels maintain their original mechanical performance and size stability when applied in aqueous environments. Researchers have developed various anti-swelling hydrogels with versatile functions in recent years, integrating anti-swelling property with characteristics like high strength, self-healing, injectability, adhesiveness, and antibacterial properties.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Article Engineering, Biomedical

Rapid and coagulation-independent haemostatic sealing by a paste inspired by barnacle glue

Hyunwoo Yuk et al.

Summary: This adhesive paste, inspired by barnacle glue, effectively seals tissues in less than 15 seconds regardless of blood coagulation rate. With a design based on adhesive proteins embedded in a lipid-rich matrix, the paste resorbs slowly over weeks and forms strong interfaces with blood-covered tissues, outperforming commercial haemostatic agents. It may be beneficial in treating severe bleeding, even in individuals with coagulopathies.

NATURE BIOMEDICAL ENGINEERING (2021)

Review Clinical Neurology

Bioadhesives in neurosurgery: a review

Liming Qiu et al.

JOURNAL OF NEUROSURGERY (2020)

Article Nanoscience & Nanotechnology

An Injectable and Instant Self-Healing Medical Adhesive for Wound Sealing

Feifei Sun et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Review Nanoscience & Nanotechnology

Overcoming the translational barriers of tissue adhesives

Gonzalo Munoz Taboada et al.

NATURE REVIEWS MATERIALS (2020)

Review Polymer Science

Status and future scope of hydrogels in wound healing: Synthesis, materials and evaluation

Jinxi Xiang et al.

EUROPEAN POLYMER JOURNAL (2020)

Article Biochemistry & Molecular Biology

Citalopram Administration Does Not Promote Function or Histological Recovery after Spinal Cord Injury

Rui Lima et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Multidisciplinary Sciences

Noninvasive in vivo 3D bioprinting

Yuwen Chen et al.

SCIENCE ADVANCES (2020)

Article Multidisciplinary Sciences

Instant tough bioadhesive with triggerable benign detachment

Xiaoyu Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

Time course of diffusion tensor imaging metrics in the chronic spinal cord compression rat model

Weipeng Zheng et al.

ACTA RADIOLOGICA (2019)

Article Chemistry, Multidisciplinary

Tetra-PEG Based Hydrogel Sealants for In Vivo Visceral Hemostasis

Yazhong Bu et al.

ADVANCED MATERIALS (2019)

Article Multidisciplinary Sciences

A strongly adhesive hemostatic hydrogel for the repair of arterial and heart bleeds

Yi Hong et al.

NATURE COMMUNICATIONS (2019)

Review Engineering, Biomedical

Multifunctional Biomedical Adhesives

Rattapol Pinnaratip et al.

ADVANCED HEALTHCARE MATERIALS (2019)

Article Biochemistry & Molecular Biology

Nonswellable and Tough Supramolecular Hydrogel Based on Strong Micelle Cross-Linkings

Zezhao Qin et al.

BIOMACROMOLECULES (2019)

Article Multidisciplinary Sciences

Dry double-sided tape for adhesion of wet tissues and devices

Hyunwoo Yuk et al.

NATURE (2019)

Article Clinical Neurology

DuraSeal Exact Is a Safe Adjunctive Treatment for Durotomy in Spine: Postapproval Study

Kee D. Kim et al.

GLOBAL SPINE JOURNAL (2019)

Article Materials Science, Biomaterials

Stiff micelle-crosslinked hyaluronate hydrogels with low swelling for potential cartilage repair

Penggang Ren et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

Article Biochemical Research Methods

Non-swelling hydrogel-based microfluidic chips

Chong Shen et al.

LAB ON A CHIP (2019)

Article Chemistry, Multidisciplinary

Bioinspired Multifunctional Hybrid Hydrogel Promotes Wound Healing

Guopu Chen et al.

ADVANCED FUNCTIONAL MATERIALS (2018)

Article Orthopedics

Acute Thoracolumbar Spinal Cord Injury Relationship of Cord Compression to Neurological Outcome

Peta Skeers et al.

JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2018)

Review Neurosciences

Experimental spinal cord trauma: a review of mechanically induced spinal cord injury in rat models

Dauda Abdullahi et al.

REVIEWS IN THE NEUROSCIENCES (2017)

Article Multidisciplinary Sciences

Tough adhesives for diverse wet surfaces

J. Li et al.

SCIENCE (2017)

Review Multidisciplinary Sciences

Advances in engineering hydrogels

Yu Shrike Zhang et al.

SCIENCE (2017)

Review Clinical Neurology

Animal models of spinal cord injury: a systematic review

M. Sharif-Alhoseini et al.

SPINAL CORD (2017)

Article Medicine, General & Internal

Traumatic spinal cord injury

Christopher S. Ahuja et al.

NATURE REVIEWS DISEASE PRIMERS (2017)

Review Chemistry, Multidisciplinary

The chemistry and engineering of polymeric hydrogel adhesives for wound closure: a tutorial

C. Ghobril et al.

CHEMICAL SOCIETY REVIEWS (2015)

Article Medicine, Research & Experimental

Comparison between self-assembling peptide nanofiber scaffold (SAPNS) and fibrin sealant in neurosurgical hemostasis

Fei-fan Xu et al.

CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2015)

Review Chemistry, Multidisciplinary

Recent progress in biomedical applications of Pluronic (PF127): Pharmaceutical perspectives

Muhammad Sajid Hamid Akash et al.

JOURNAL OF CONTROLLED RELEASE (2015)

Review Anatomy & Morphology

Injectable Hydrogels for Spinal Cord Repair: A Focus on Swelling and Intraspinal Pressure

Zin Z. Khaing et al.

CELLS TISSUES ORGANS (2015)

Article Clinical Neurology

The use of surgical sealants in the repair of dural tears during non-instrumented spinal surgery

Massimo Miscusi et al.

EUROPEAN SPINE JOURNAL (2014)

Review Polymer Science

The chemistry of tissue adhesive materials

Petra J. M. Bouten et al.

PROGRESS IN POLYMER SCIENCE (2014)

Article Multidisciplinary Sciences

Nonswellable Hydrogel Without Mechanical Hysteresis

Hiroyuki Kamata et al.

SCIENCE (2014)

Article Cell Biology

A Blood-Resistant Surgical Glue for Minimally Invasive Repair of Vessels and Heart Defects

Nora Lang et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Article Engineering, Biomedical

Mechanically Robust, Negative-Swelling, Mussel-Inspired Tissue Adhesives

Devin G. Barrett et al.

ADVANCED HEALTHCARE MATERIALS (2013)

Article Engineering, Biomedical

Formulation and characterization of poloxamine-based hydrogels as tissue sealants

Eunhee Cho et al.

ACTA BIOMATERIALIA (2012)

Article Orthopedics

Cauda Equina Syndrome After a TLIF Resulting From Postoperative Expansion of a Hydrogel Dural Sealant

Brian J. Neuman et al.

CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (2012)

Article Engineering, Biomedical

A novel synthetic route for the preparation of hydrolytically degradable synthetic hydrogels

Eunhee Cho et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2009)

Letter Clinical Neurology

Posture-related cough headache and orthostatic drop in lumbar CSF pressure

F Bono et al.

JOURNAL OF NEUROLOGY (2005)

Article Chemistry, Multidisciplinary

A new approach to bioconjugates for proteins and peptides (pegylation) utilising living radical polymerisation

F Lecolley et al.

CHEMICAL COMMUNICATIONS (2004)

Article Engineering, Biomedical

Photo-crosslinkable, thermo-sensitive and biodegradable Pluronic hydrogels for sustained release of protein

JB Lee et al.

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2004)