4.8 Article

A Nanoplasmonic Portable Molecular Interaction Platform for High-Throughput Drug Screening

Related references

Note: Only part of the references are listed.
Review Biotechnology & Applied Microbiology

Insights on the emerging biotechnology of histidine-rich peptides

Hector Lopez-Laguna et al.

Summary: The discovery of restriction enzymes in the late 70's enabled the production of functional proteins through recombinant DNA technologies, greatly benefiting biotechnological and pharmaceutical industries. Hexahistidine peptide (H6) has become the gold standard for purification tags in protein production, and histidine-rich peptides are proving to have broad applications in various fields.

BIOTECHNOLOGY ADVANCES (2022)

Article Medical Laboratory Technology

Diagnostic Value of Nucleocapsid Protein in Blood for SARS-CoV-2 Infection

Yu Zhang et al.

Summary: Serum nucleocapsid protein of SARS-CoV-2 is a biomarker for acute infection with high diagnostic sensitivity and specificity, which correlates to disease severity and inversely relates to antibody levels.

CLINICAL CHEMISTRY (2022)

Article Chemistry, Analytical

Surface Plasmon Resonance Assay for Label-Free and Selective Detection of HIV-1 p24 Protein

Lucia Sarcina et al.

Summary: The study developed a reliable and label-free detection method for HIV-1 p24 protein using multi-parameter SPR. Different antibody immobilization techniques on the surface led to varying coverage and binding signals. The chemically modified system showed improved sensitivity and selectivity in detecting HIV-1 p24.

BIOSENSORS-BASEL (2021)

Article Immunology

Recent advances in SARS-CoV-2 Spike protein and RBD mutations comparison between new variants Alpha (B.1.1.7, United Kingdom), Beta (B.1.351, South Africa), Gamma (P.1, Brazil) and Delta (B.1.617.2, India)

Paulo R. S. Sanches et al.

Summary: New variants of SARS-CoV-2 Alpha, Beta, Gamma, and Delta have rapidly spread in various countries, and mutations in the RBD spike protein may lead to increased infectivity compared to the Wuhan 2019 strain.

JOURNAL OF VIRUS ERADICATION (2021)

Article Biophysics

One-step rapid quantification of SARS-CoV-2 virus particles via low-cost nanoplasmonic sensors in generic microplate reader and point-of-care device

Liping Huang et al.

Summary: The rapid, accurate, and convenient detection of SARS-CoV-2 virus is crucial in controlling the ongoing global pandemic. A new method developed allows for rapid and direct optical measurement of virus particles with minimal sample preparation, showing promise for quick adoption in clinical and resource-limited settings.

BIOSENSORS & BIOELECTRONICS (2021)

Article Biochemical Research Methods

Protein interaction interface region prediction by geometric deep learning

Bowen Dai et al.

Summary: The article introduces a unified Geometric Deep Neural Network, PInet, which combines data-driven and physics-driven methods to predict protein interaction interfaces. In testing, PInet simultaneously predicts interface regions on interacting proteins and shows better performance than the state-of-the-art predictor.

BIOINFORMATICS (2021)

Review Environmental Sciences

A critical review on silver nanoparticles: From synthesis and applications to its mitigation through low-cost adsorption by biochar

Md Anwarul Islam et al.

Summary: Silver nanoparticles are widely used in various products due to their exceptional antimicrobial properties and surface plasmon resonance. However, the environmental pollution caused by the release of silver nanoparticles is becoming increasingly serious, especially affecting aquatic ecosystems. It is crucial to reduce the toxic effects of silver nanoparticles and adhere to regulatory guidelines in order to protect the environment.

JOURNAL OF ENVIRONMENTAL MANAGEMENT (2021)

Article Reproductive Biology

Targeting novel coronavirus SARS-CoV-2 spike protein with phytoconstituents of Momordica charantia

Santosh Kumar Singh et al.

Summary: The study identified phytoconstituents from bitter melon as potential agents to treat SARS-CoV-2 viral infections due to their binding to spike proteins S1 and S2. In-silico evaluations showed low binding energy range, while docking, ADME properties, and SPR displayed strong interactions between phytoconstituents and the active site of the SARS-CoV-2 spike protein.

JOURNAL OF OVARIAN RESEARCH (2021)

Review Chemistry, Physical

Data evaluation for surface-sensitive label-free methods to obtain real-time kinetic and structural information of thin films: A practical review with related software packages

Andras Saftics et al.

Summary: Interfacial layers play a crucial role in various fields, and label-free surface sensitive methods are excellent for monitoring the formation kinetics and structural evolution of thin layers. This paper reviews existing label-free techniques and emphasizes the importance of combining these methods to extract kinetic and structural information effectively.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2021)

Review Virology

Neutralizing Antibody Therapeutics for COVID-19

Aeron C. Hurt et al.

Summary: The emergence of SARS-CoV-2 and the subsequent COVID-19 pandemic have created an urgent need for effective therapeutic strategies. Neutralizing antibodies have shown potential in treating and preventing COVID-19, but their efficacy in severe cases remains varied. Treatment may lead to the formation of antiviral resistant escape mutants, highlighting the importance of exploring strategies to minimize risk.

VIRUSES-BASEL (2021)

Review Chemistry, Analytical

Surface Plasmonic Sensors: Sensing Mechanism and Recent Applications

Qilin Duan et al.

Summary: The recent progress in surface plasmonic sensors, focusing on planar metastructures and optical-fiber waveguides, as well as the use of sensors based on LSPR, hyperbolic dispersion, Fano resonance, and 2D materials integration, was presented in this review. The integration of LSPR/SPR structures and 2D materials in optical-fiber sensors was also summarized, along with advances in quantum plasmonic sensing beyond the classical shot noise limit. Challenges and opportunities in this field were discussed.

SENSORS (2021)

Article Cell Biology

Highly specific monoclonal antibodies and epitope identification against SARS-CoV-2 nucleocapsid protein for antigen detection tests

Yutaro Yamaoka et al.

Summary: This study produced monoclonal antibodies that exclusively react with SARS-CoV-2 with no cross-reactivity with other human coronaviruses, suitable for detecting the virus in clinical samples. The antibodies were selected and used to develop an immuno-chromatographic assay augmented with silver amplification technology, capable of detecting current circulating variants of concern. These antibodies can serve as good candidates for developing antigen detection kits for COVID-19 due to their high performance.

CELL REPORTS MEDICINE (2021)

Article Multidisciplinary Sciences

Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2

Renhong Yan et al.

SCIENCE (2020)

Article Biochemistry & Molecular Biology

A lanthipeptide library used to identify a protein-protein interaction inhibitor

Xiao Yang et al.

NATURE CHEMICAL BIOLOGY (2018)

Review Pharmacology & Pharmacy

Kinetics for Drug Discovery: an industry-driven effort to target drug residence time

Doris A. Schuetz et al.

DRUG DISCOVERY TODAY (2017)

Article Biochemistry & Molecular Biology

Effect of His-Tag on Expression, Purification, and Structure of Zinc Finger Protein, ZNF191(243-368)

Dongxin Zhao et al.

BIOINORGANIC CHEMISTRY AND APPLICATIONS (2016)

Article Energy & Fuels

Growth, characterization and performance evaluation of Ti/AlTiN/AlTiON/AlTiO high temperature

Harish C. Barshilia

SOLAR ENERGY MATERIALS AND SOLAR CELLS (2014)

Review Chemistry, Multidisciplinary

Molecular Interaction of Proteins and Peptides with Nanoparticles

Anton A. Shemetov et al.

ACS NANO (2012)

Article Chemistry, Multidisciplinary

Greener Electrochemical Synthesis of High Quality Graphene Nanosheets Directly from Pencil and its SPR Sensing Application

Virendra V. Singh et al.

ADVANCED FUNCTIONAL MATERIALS (2012)

Review Biochemistry & Molecular Biology

Surface Plasmon Resonance Biosensors Incorporating Gold Nanoparticles

Erin E. Bedford et al.

MACROMOLECULAR BIOSCIENCE (2012)

Article Chemistry, Multidisciplinary

Facile Fabrication of Two-Dimensionally Ordered Macroporous Silver Thin Films and Their Application in Molecular Sensing

Guosong Hong et al.

ADVANCED FUNCTIONAL MATERIALS (2010)

Article Biochemistry & Molecular Biology

Optical Biosensing

Jo Leanna Wilson et al.

BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION (2010)

Article Biochemical Research Methods

Label-Free Detection of Biomolecular Interactions Using BioLayer Interferometry for Kinetic Characterization

Joy Concepcion et al.

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2009)

Review Chemistry, Multidisciplinary

Surface plasmon resonance sensors for detection of chemical and biological species

Jiri Homola

CHEMICAL REVIEWS (2008)

Article Oncology

Her2-positive breast cancer: Herceptin and beyond

Windy Dean-Colomb et al.

EUROPEAN JOURNAL OF CANCER (2008)

Article Biotechnology & Applied Microbiology

Severe acute respiratory syndrome vaccine efficacy in ferrets: whole killed virus and adenovirus-vectored vaccines

Raymond H. See et al.

JOURNAL OF GENERAL VIROLOGY (2008)

Article Biophysics

Concentration dependence of IgG-protein A affinity studied by wireless-electrodeless QCM

Hirotsugu Ogi et al.

BIOSENSORS & BIOELECTRONICS (2007)

Article Biochemistry & Molecular Biology

SPR for molecular interaction analysis: a review of emerging application areas

R Karlsson

JOURNAL OF MOLECULAR RECOGNITION (2004)

Review Biochemistry & Molecular Biology

Surface plasmon resonance: towards an understanding of the mechanisms of biological molecular recognition

JM McDonnell

CURRENT OPINION IN CHEMICAL BIOLOGY (2001)