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CELL (2015)
Delivery and Specificity of CRISPR/Cas9 Genome Editing Technologies for Human Gene Therapy
Jennifer L. Gori et al.
HUMAN GENE THERAPY (2015)
Separation of cancer cells from white blood cells by pinched flow fractionation
Marie Podenphant et al.
LAB ON A CHIP (2015)
Lab on a chip for continuous-flow magnetic cell separation
Majid Hejazian et al.
LAB ON A CHIP (2015)
Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples
Wenfei Jin et al.
NATURE (2015)
Single-cell chromatin accessibility reveals principles of regulatory variation
Jason D. Buenostro et al.
NATURE (2015)
Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state
Assaf Rotem et al.
NATURE BIOTECHNOLOGY (2015)
Integrated genome and transcriptome sequencing of the same cell
Siddharth S. Dey et al.
NATURE BIOTECHNOLOGY (2015)
Biodegradable silicon nanoneedles delivering nucleic acids intracellularly induce localized in vivo neovascularization
C. Chiappini et al.
NATURE MATERIALS (2015)
A microfluidic device for label-free, physical capture of circulating tumor cell clusters
A. Fatih Sarioglu et al.
NATURE METHODS (2015)
G&T-seq: parallel sequencing of single-cell genomes and transcriptomes
Iain C. Macaulay et al.
NATURE METHODS (2015)
Multiplexed locus-specific analysis of DNA methylation in single cells
Lih Feng Cheow et al.
NATURE PROTOCOLS (2015)
Profiling DNA methylome landscapes of mammalian cells with single-cell reduced-representation bisulfite sequencing
Hongshan Guo et al.
NATURE PROTOCOLS (2015)
Acoustic separation of circulating tumor cells
Peng Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands
Yao Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Spatially resolved, highly multiplexed RNA profiling in single cells
Kok Hao Chen et al.
SCIENCE (2015)
Single-cell-initiated monosynaptic tracing reveals layer-specific cortical network modules
Adrian Wertz et al.
SCIENCE (2015)
Single-Cell DNA Methylome Sequencing and Bioinformatic Inference of Epigenomic Cell-State Dynamics
Matthias Farlik et al.
CELL REPORTS (2015)
Fundamentals and application of magnetic particles in cell isolation and enrichment: a review
Brian D. Plouffe et al.
REPORTS ON PROGRESS IN PHYSICS (2015)
Purification of regulatory T cells with the use of a fully enclosed high-speed microfluidic system
Ruud Hulspas et al.
CYTOTHERAPY (2014)
Cell culture monitoring for drug screening and cancer research: a transparent, microfluidic, multi-sensor microsystem
Andreas Weltin et al.
LAB ON A CHIP (2014)
Single-cell RNA-seq reveals dynamic paracrine control of cellular variation
Alex K. Shalek et al.
NATURE (2014)
Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity
Sebastien A. Smallwood et al.
NATURE METHODS (2014)
Single-cell western blotting
Alex J. Hughes et al.
NATURE METHODS (2014)
Single-cell in situ RNA profiling by sequential hybridization
Eric Lubeck et al.
NATURE METHODS (2014)
Full-length RNA-seq from single cells using Smart-seq2
Simone Picelli et al.
NATURE PROTOCOLS (2014)
Multivariate biophysical markers predictive of mesenchymal stromal cell multipotency
Wong Cheng Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics
Charles Gawad et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Cell separation using tilted-angle standing surface acoustic waves
Xiaoyun Ding et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Highly Multiplexed Subcellular RNA Sequencing in Situ
Je Hyuk Lee et al.
SCIENCE (2014)
Force-controlled manipulation of single cells: from AFM to FluidFM
Orane Guillaume-Gentil et al.
TRENDS IN BIOTECHNOLOGY (2014)
Biopsy with Thermally-Responsive Untethered Microtools
Evin Gultepe et al.
ADVANCED MATERIALS (2013)
Local Delivery of Molecules from a Nanopipette for Quantitative Receptor Mapping on Live Cells
Babak Babakinejad et al.
ANALYTICAL CHEMISTRY (2013)
Nanofountain Probe Electroporation (NFP-E) of Single Cells
Wonmo Kang et al.
NANO LETTERS (2013)
Single-cell Hi-C reveals cell-to-cell variability in chromosome structure
Takashi Nagano et al.
NATURE (2013)
In situ sequencing for RNA analysis in preserved tissue and cells
Rongqin Ke et al.
NATURE METHODS (2013)
Single-cell analysis and sorting using droplet-based microfluidics
Linas Mazutis et al.
NATURE PROTOCOLS (2013)
Optimization of scarless human stem cell genome editing
Luhan Yang et al.
NUCLEIC ACIDS RESEARCH (2013)
A vector-free microfluidic platform for intracellular delivery
Armon Sharei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Single-Cell DNA-Methylation Analysis Reveals Epigenetic Chimerism in Preimplantation Embryos
Chanchao Lorthongpanich et al.
SCIENCE (2013)
Inertial Focusing for Tumor Antigen-Dependent and -Independent Sorting of Rare Circulating Tumor Cells
Emre Ozkumur et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Multifunctional T-cell Analyses to Study Response and Progression in Adoptive Cell Transfer Immunotherapy
Chao Ma et al.
CANCER DISCOVERY (2013)
Microfluidic Devices for Electrochemical Measurement of Photosynthetic Activity of Cyanobacteria Microcystis Cells
Masahiro KOIDE et al.
ANALYTICAL SCIENCES (2012)
ApoStream™, a new dielectrophoretic device for antibody independent isolation and recovery of viable cancer cells from blood
Vishal Gupta et al.
BIOMICROFLUIDICS (2012)
Single-Cell Exome Sequencing Reveals Single-Nucleotide Mutation Characteristics of a Kidney Tumor
Xun Xu et al.
CELL (2012)
Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells
Qihui Shi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Polyfunctional responses by human T cells result from sequential release of cytokines
Qing Han et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a Single Human Cell
Chenghang Zong et al.
SCIENCE (2012)
Using Gene Expression Noise to Understand Gene Regulation
Brian Munsky et al.
SCIENCE (2012)
Micromachine-Enabled Capture and Isolation of Cancer Cells in Complex Media
Shankar Balasubramanian et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
Controlled manipulation of multiple cells using catalytic microbots
Samuel Sanchez et al.
CHEMICAL COMMUNICATIONS (2011)
Continuous separation of breast cancer cells from blood samples using multi-orifice flow fractionation (MOFF) and dielectrophoresis (DEP)
Hui-Sung Moon et al.
LAB ON A CHIP (2011)
Enhancement by optical force of separation in pinched flow fractionation
Kyung Heon Lee et al.
LAB ON A CHIP (2011)
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
Sean C. Bendall et al.
SCIENCE (2011)
Microfluidic cell arrays for metabolic monitoring of stimulated cardiomyocytes
Wei Cheng et al.
ELECTROPHORESIS (2010)
B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression
Jonathan M. Irish et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Isolation of circulating tumor cells using a microvortex-generating herringbone-chip
Shannon L. Stott et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
PEG-conjugated PAMAM Dendrimers Mediate Efficient Intramuscular Gene Expression
Rong Qi et al.
AAPS JOURNAL (2009)
Inertial microfluidics for continuous particle separation in spiral microchannels
Sathyakumar S. Kuntaegowdanahalli et al.
LAB ON A CHIP (2009)
FluidFM: Combining Atomic Force Microscopy and Nanofluidics in a Universal Liquid Delivery System for Single Cell Applications and Beyond
Andre Meister et al.
NANO LETTERS (2009)
Droplet microfluidic technology for single-cell high-throughput screening
Eric Brouzes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Continuous particle separation in spiral microchannels using dean flows and differential migration
Ali Asgar S. Bhagat et al.
LAB ON A CHIP (2008)
Selection of mammalian cells based on their cell-cycle phase using dielectrophoresis
Unyoung Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Isolation of rare circulating tumour cells in cancer patients by microchip technology
Sunitha Nagrath et al.
NATURE (2007)
Continuous inertial focusing, ordering, and separation of particles in microchannels
Dino Di Carlo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
DNA-encoded antibody libraries: A unified platform for multiplexed cell sorting and detection of genes and proteins
Ryan C. Bailey et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
A microengraving method for rapid selection of single cells producing antigen-specific antibodies
J. Christopher Love et al.
NATURE BIOTECHNOLOGY (2006)
Large-scale single-cell trapping and imaging using microwell arrays
JR Rettig et al.
ANALYTICAL CHEMISTRY (2005)
Massively parallel manipulation of single cells and microparticles using optical images
PY Chiou et al.
NATURE (2005)
Microfluidics: Fluid physics at the nanoliter scale
TM Squires et al.
REVIEWS OF MODERN PHYSICS (2005)
Microfluidic sorting of mammalian cells by optical force switching
MM Wang et al.
NATURE BIOTECHNOLOGY (2005)
Pinched flow fractionation: Continuous size separation of particles utilizing a laminar flow profile in a pinched microchannel
M Yamada et al.
ANALYTICAL CHEMISTRY (2004)
Continuous particle separation through deterministic lateral displacement
LR Huang et al.
SCIENCE (2004)
Progress and problems with the use of viral vectors for gene therapy
CE Thomas et al.
NATURE REVIEWS GENETICS (2003)
Formation of dispersions using flow focusing in microchannels
SL Anna et al.
APPLIED PHYSICS LETTERS (2003)
Microfluidic large-scale integration
T Thorsen et al.
SCIENCE (2002)
Dynamic pattern formation in a vesicle-generating microfluidic device
T Thorsen et al.
PHYSICAL REVIEW LETTERS (2001)
Monolithic microfabricated valves and pumps by multilayer soft lithography
MA Unger et al.
SCIENCE (2000)