3.8 Article

Carbon-based nanomaterials in gene therapy

Related references

Note: Only part of the references are listed.
Review Pharmacology & Pharmacy

Doxorubicin-loaded graphene oxide nanocomposites in cancer medicine: stimuli-responsive carriers, co-delivery and suppressing resistance

Milad Ashrafizadeh et al.

Summary: Graphene oxide (GO) nanostructures can effectively deliver doxorubicin and enhance its cytotoxicity against cancer cells. By preparing stimuli-responsive GO nanocomposites, surface functionalization, and hybrid nanoparticles, the therapeutic potential of doxorubicin in cancer therapy can be maximized.

EXPERT OPINION ON DRUG DELIVERY (2022)

Article Nanoscience & Nanotechnology

Dynamics of Antimicrobial Peptide Encapsulation in Carbon Nanotubes: The Role of Hydroxylation

Maryam Zarghami Dehaghani et al.

Summary: This study discusses the encapsulation dynamics of an antimicrobial peptide in CNTs and HCNTs. The results show that the van der Waals interaction energy and free energy of the peptide complexes with CNTs and HCNTs are negative, indicating spontaneous encapsulation. HCNTs exhibit a more stable encapsulation, possibly due to the presence of electrostatic and van der Waals interactions.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2022)

Review Nanoscience & Nanotechnology

How Advancing are Mesoporous Silica Nanoparticles? A Comprehensive Review of the Literature

Sahar Porrang et al.

Summary: This review article summarizes the applications and research progress of mesoporous silica nanoparticles. It discusses the synthesis methods using different sources, the parameters affecting their properties and functionalization, and the novel strategies for drug delivery and cancer treatment based on these nanoparticles.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2022)

Article Nanoscience & Nanotechnology

MXene-Graphene Composites: A Perspective on Biomedical Potentials

Ebrahim Mostafavi et al.

Summary: MXenes and graphene, as promising two-dimensional materials, have unique physicochemical properties that make them suitable for future biomedical applications. Their hybrid/composite structure can meet the high-performance requirements in medicine and biomedical engineering. However, more research is needed on the hybridization, surface functionalization, and toxicological effects, as well as clinical translation evaluations. Overall, the MXene-graphene composites have the potential to open up new horizons in healthcare and medicine.

NANO-MICRO LETTERS (2022)

Review Materials Science, Multidisciplinary

Eco-friendly synthesis of carbon nanotubes and their cancer theranostic applications

Ebrahim Mostafavi et al.

Summary: Carbon nanotubes (CNTs) with attractive physicochemical characteristics have been widely studied in different fields of science. Plenty of studies have been conducted to find innovative, eco-friendly, and inexpensive methods for their fabrication. Natural hydrocarbon precursors, including plant extracts and agricultural bio-wastes, have been widely used in synthesizing CNTs. Furthermore, multifunctionalized CNTs with improved biocompatibility and targeting features show promise in cancer theranostic applications.

MATERIALS ADVANCES (2022)

Article Engineering, Biomedical

Two-Dimensional Nanomaterials beyond Graphene for Biomedical Applications

Maryam Derakhshi et al.

Summary: This review explores the potential of two-dimensional (2D) nanomaterials beyond graphene in biomedical applications. In addition to graphene, other 2D materials such as transition metal dichalcogenides, topological insulators, phosphorene, antimonene, etc. possess unique physicochemical properties and can be used in bioelectronics, imaging, drug delivery, tissue engineering, and regenerative medicine.

JOURNAL OF FUNCTIONAL BIOMATERIALS (2022)

Review Materials Science, Composites

Graphene, Graphene-Derivatives and Composites: Fundamentals, Synthesis Approaches to Applications

Dibyani Sahu et al.

Summary: Graphene has gained significant notoriety and interest in the scientific world due to its unique properties, with various preparation methods developed and extensive applications found in different fields. This article focuses on summarizing the advancements in graphene research regarding its strategies and applications.

JOURNAL OF COMPOSITES SCIENCE (2021)

Review Nanoscience & Nanotechnology

Nanostructured diamond for biomedical applications

Prem C. Pandey et al.

Summary: Nanostructured forms of diamond have unique properties suitable for medical devices. Synthesized through various methods to enhance biocompatibility and cell attachment, they improve interactions with bone cells, imaging, gene therapy, and drug delivery in medical applications.

NANOTECHNOLOGY (2021)

Review Nanoscience & Nanotechnology

Carbon Nanotubes: Smart Drug/GeneDelivery Carriers

Hossein Zare et al.

Summary: Carbon nanotubes have unique properties that make them suitable for drug and gene delivery, as well as applications in cancer therapy, anti-inflammatory treatments, and phototherapy. However, concerns about nanotoxicity and environmental impact remain, despite decades of research and potential benefits.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Article Chemistry, Multidisciplinary

Temperature-Sensitive Lipid-Coated Carbon Nanotubes for Synergistic Photothermal Therapy and Gene Therapy

Yinan Zhao et al.

Summary: The combination of peptide lipid (PL) and sucrose laurate (SL) coated carbon nanotubes has shown great potential for achieving controlled release of genes for anti-tumor activity through photothermal effects. The resulting SCNT-PS/siRNA delivery system exhibited high anti-tumor activity and efficient systemic delivery to tumor sites.

ACS NANO (2021)

Article Materials Science, Multidisciplinary

Nanodiamonds: Synthesis, properties, and applications in nanomedicine

Jin-Xu Qin et al.

Summary: Nanodiamonds have excellent properties for various potential applications in nanomedicine, with significant progress being made in recent years, especially in bioimaging, drug delivery, and biosensing. There is a promising outlook for their future developments and applications.

MATERIALS & DESIGN (2021)

Review Chemistry, Multidisciplinary

Recent Advances in Stimulus-Responsive Nanocarriers for Gene Therapy

Cheng Yu et al.

Summary: Gene therapy presents a promising approach for treating genetic disorders, but challenges remain with viral vectors. The emergence of nanomedicine has revolutionized the field of gene therapy, with recent advancements in stimulus-responsive nonviral nanocarriers showing high efficiency in delivering therapeutic nucleic acids.

ADVANCED SCIENCE (2021)

Article Engineering, Biomedical

Discrimination of single-point mutations in unamplified genomic DNA via Cas9 immobilized on a graphene field-effect transistor

Sarah Balderston et al.

Summary: Liquid-gated graphene field-effect transistors can distinguish single-point mutations in human genomic samples, opening up new possibilities for genetic research and diagnostics.

NATURE BIOMEDICAL ENGINEERING (2021)

Review Pharmacology & Pharmacy

Non-viral Vectors in Gene Therapy: Recent Development, Challenges, and Prospects

Hui Zu et al.

Summary: Although non-viral vectors in gene therapy have low cytotoxicity and immunogenicity, they still face challenges in gene transfer efficiency, specificity, gene expression duration, and safety. Overcoming these obstacles is necessary to enhance the effectiveness of non-viral vectors in gene therapy.

AAPS JOURNAL (2021)

Article Nanoscience & Nanotechnology

Tailoring the Architecture of Cationic Polymer Brush-Modified Carbon Nanotubes for Efficient siRNA Delivery in Cancer Immunotherapy

Danyang Li et al.

Summary: The study demonstrates the controlled grafting of cationic polymers on carbon nanotubes, revealing the highly architectural-dependent behavior of different brush-CNT hybrids in binding with nucleic acids. Furthermore, the different chemistries of the brush coatings were found to influence biocompatibility, cellular uptake, and silencing efficiency in vitro.

ACS APPLIED MATERIALS & INTERFACES (2021)

Review Engineering, Biomedical

Recent advances in carbon nanomaterials for biomedical applications: A review

Parand R. Riley et al.

Summary: Carbon nanostructures play a crucial role in biomedical research, with a focus on drug delivery, cancer therapy, and antiviral applications. Challenges include reducing toxicity, enhancing biocompatibility, and improving water solubility.

CURRENT OPINION IN BIOMEDICAL ENGINEERING (2021)

Article Chemistry, Multidisciplinary

Harnessing subcellular-resolved organ distribution of cationic copolymer-functionalized fluorescent nanodiamonds for optimal delivery of active siRNA to a xenografted tumor in mice

Sandra Claveau et al.

Summary: Nanodiamonds can transport active drugs in vivo, but methods for accurately determining their bioavailability are lacking. By making nanodiamonds fluorescent and developing an automated quantification method, we achieved high-resolution imaging with single-particle sensitivity in mouse organ and tumor tissue sections.

NANOSCALE (2021)

Review Chemistry, Multidisciplinary

Hybrid carbon-based materials for gene delivery in cancer therapy

Sahar Taghavi et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Review Gastroenterology & Hepatology

Autophagy in hepatic adaptation to stress

Younis Hazari et al.

JOURNAL OF HEPATOLOGY (2020)

Review Materials Science, Multidisciplinary

A review of graphene synthesis by indirect and direct deposition methods

Yanxia Wu et al.

JOURNAL OF MATERIALS RESEARCH (2020)

Article Nanoscience & Nanotechnology

Functionalized Folate-Modified Graphene Oxide/PEI siRNA Nanocomplexes for Targeted Ovarian Cancer Gene Therapy

Yunfei Wang et al.

NANOSCALE RESEARCH LETTERS (2020)

Article Plant Sciences

Carbon Dots for Efficient Small Interfering RNA Delivery and Gene Silencing in Plants

Steven H. Schwartz et al.

PLANT PHYSIOLOGY (2020)

Review Dentistry, Oral Surgery & Medicine

Fullerene and its applications: A review

Poulomi Bhakta et al.

JOURNAL OF INDIAN ACADEMY OF ORAL MEDICINE AND RADIOLOGY (2020)

Review Pharmacology & Pharmacy

Fullerene-based delivery systems

Houman Kazemzadeh et al.

DRUG DISCOVERY TODAY (2019)

Article Biotechnology & Applied Microbiology

Carbon nanotube-delivered iC9 suicide gene therapy for killing breast cancer cells in vitro

Masoud Mohseni-Dargah et al.

NANOMEDICINE (2019)

Article Biochemistry & Molecular Biology

Carbon dot festooned and surface passivated graphene-reinforced chitosan construct for tumor-targeted delivery of TNF-α gene

Jumana Abdul Jaleel et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Article Chemistry, Multidisciplinary

Graphene at Fifteen

Ruquan Ye et al.

ACS NANO (2019)

Article Biochemical Research Methods

Carbon nanotube-mediated DNA delivery without transgene integration in intact plants

Gozde S. Demirer et al.

NATURE PROTOCOLS (2019)

Review Biotechnology & Applied Microbiology

Small molecules derived carbon dots: synthesis and applications in sensing, catalysis, imaging, and biomedicine

Anirudh Sharma et al.

JOURNAL OF NANOBIOTECHNOLOGY (2019)

Article Toxicology

Multi-walled carbon nanotube oxidation dependent keratinocyte cytotoxicity and skin inflammation

Brian C. Palmer et al.

PARTICLE AND FIBRE TOXICOLOGY (2019)

Review Materials Science, Biomaterials

Three-Dimensional Graphene Foams: Synthesis, Properties, Biocompatibility, Biodegradability, and Applications in Tissue Engineering

Hamed Amani et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2019)

Article Chemistry, Multidisciplinary

Microfluidic manufacturing of surface-functionalized graphene oxide nanoflakes for gene delivery

Riccardo Di Santo et al.

NANOSCALE (2019)

Review Engineering, Multidisciplinary

A critical review of nanodiamond based nanocomposites: Synthesis, properties and applications

Yinhang Zhang et al.

COMPOSITES PART B-ENGINEERING (2018)

Article Environmental Sciences

Size dependent oxidative stress response of the gut of Daphnia magna to functionalized nanodiamond particles

Gustavo A. Dominguez et al.

ENVIRONMENTAL RESEARCH (2018)

Article Chemistry, Multidisciplinary

Graphene oxide-mediated Cas9/sgRNA delivery for efficient genome editing

Huahua Yue et al.

NANOSCALE (2018)

Article Chemistry, Multidisciplinary

Dual-Function, Cationic, Peptide-Coated Nanodiamond Systems: Facilitating Nuclear-Targeting Delivery for Enhanced Gene Therapy Applications

Hoi Man Leung et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2018)

Review Immunology

Type 2 Immune Mechanisms in Carbon Nanotube-Induced Lung Fibrosis

Jie Dong et al.

FRONTIERS IN IMMUNOLOGY (2018)

Article Biochemistry & Molecular Biology

Graphene-based materials: The missing piece in nanomedicine?

Tanveer A. Tabish

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

Gene Delivery to Tobacco Root Cells with Single-Walled Carbon Nanotubes and Cell-Penetrating Fusogenic Peptides

Arezoo Golestanipour et al.

MOLECULAR BIOTECHNOLOGY (2018)

Review Metallurgy & Metallurgical Engineering

UNLIMITED POTENTIALS OF CARBON: DIFFERENT STRUCTURES AND USES (A REVIEW)

Onyeka Stanislaus Okwundu et al.

METALLURGICAL & MATERIALS ENGINEERING (2018)

Review Biochemistry & Molecular Biology

Graphene materials as 2D non-viral gene transfer vector platforms

M. Vincent et al.

GENE THERAPY (2017)

Article Chemistry, Physical

Spectroscopic Insights into Carbon Dot Systems

Marcello Righetto et al.

JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2017)

Article Chemistry, Multidisciplinary

Hyaluronic acid-based carbon dots for efficient gene delivery and cell imaging

Hai-Jiao Wang et al.

RSC ADVANCES (2017)

Review Chemistry, Physical

Recent progress in carbon quantum dots: synthesis, properties and applications in photocatalysis

Ru Wang et al.

JOURNAL OF MATERIALS CHEMISTRY A (2017)

Article Materials Science, Biomaterials

Polymer cloaking modulates the carbon nanotube protein corona and delivery into cancer cells

Januka Budhathoki-Uprety et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

Article Multidisciplinary Sciences

Graphene Quantum Dots for Cell Proliferation, Nucleus Imaging, and Photoluminescent Sensing Applications

Mukesh Kumar Kumawat et al.

SCIENTIFIC REPORTS (2017)

Article Nanoscience & Nanotechnology

In Vivo Fate of Carbon Nanotubes with Different Physicochemical Properties for Gene Delivery Applications

Anna Cifuentes-Rius et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

Review Chemistry, Multidisciplinary

Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

Mahdi Karimi et al.

CHEMICAL SOCIETY REVIEWS (2016)

Review Biochemistry & Molecular Biology

Safety and biocompatibility of graphene: A new generation nanomaterial for biomedical application

S. Syama et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2016)

Review Medicine, Legal

A review of toxicity studies of single-walled carbon nanotubes in laboratory animals

Makoto Ema et al.

REGULATORY TOXICOLOGY AND PHARMACOLOGY (2016)

Review Nanoscience & Nanotechnology

Synthesis of graphene

Md. Sajibul Alam Bhuyan et al.

INTERNATIONAL NANO LETTERS (2016)

Review Pharmacology & Pharmacy

Carbon nanotubes part I: preparation of a novel and versatile drug-delivery vehicle

Mandi Karimi et al.

EXPERT OPINION ON DRUG DELIVERY (2015)

Article Chemistry, Multidisciplinary

Single and repeated dose toxicity of citric acid-based carbon dots and a derivative in mice

Xiao Zheng et al.

RSC ADVANCES (2015)

Article Chemistry, Multidisciplinary

Implications of surface passivation on physicochemical and bioimaging properties of carbon dots

Abhay Sachdev et al.

RSC ADVANCES (2014)

Article Pharmacology & Pharmacy

Non-covalent functionalization of single-walled carbon nanotubes with modified polyethyleneimines for efficient gene delivery

Behzad Behnam et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)

Article Materials Science, Biomaterials

Highly dispersible PEGylated graphene/Au composites as gene delivery vector and potential cancer therapeutic agent

Fang-Fang Cheng et al.

JOURNAL OF MATERIALS CHEMISTRY B (2013)

Article Biophysics

Synthesis, dispersion, and cytocompatibility of graphene oxide and reduced graphene oxide

Malgorzata Wojtoniszak et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2012)

Article Chemistry, Multidisciplinary

Chromatographic Separation of Highly Soluble Diamond Nanoparticles Prepared by Polyglycerol Grafting

Li Zhao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Article Multidisciplinary Sciences

In vivo gene delivery by cationic tetraamino fullerene

Rui Maeda-Mamiya et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Chemistry, Multidisciplinary

Microwave synthesis of fluorescent carbon nanoparticles with electrochemiluminescence properties

Hui Zhu et al.

CHEMICAL COMMUNICATIONS (2009)

Article Chemistry, Multidisciplinary

Facile preparation of low cytotoxicity fluorescent carbon nanocrystals by electrooxidation of graphite

Qiao-Ling Zhao et al.

CHEMICAL COMMUNICATIONS (2008)

Editorial Material Biotechnology & Applied Microbiology

The long and short of carbon nanotube toxicity

Kostas Kostarelos

NATURE BIOTECHNOLOGY (2008)

Article Chemistry, Multidisciplinary

Surface functionalized carbogenic quantum dots

Athanasios B. Bourlinos et al.

SMALL (2008)

Article Chemistry, Multidisciplinary

Quantum-sized carbon dots for bright and colorful photoluminescence

Ya-Ping Sun et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

Article Medicine, Research & Experimental

Nonviral gene delivery by tetraamino fullerene

Hiroyuki Isobe et al.

MOLECULAR PHARMACEUTICS (2006)

Article Biochemistry & Molecular Biology

Acute myocardial infarction and heart failure: Role of apoptosis

Antonio Abbate et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2006)

Article Chemistry, Multidisciplinary

Functionalized carbon nanotubes for plasmid DNA gene delivery

D Pantarotto et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)

Article Biochemistry & Molecular Biology

Immune responses to gene therapy vectors: influence on vector function and effector mechanisms

N Bessis et al.

GENE THERAPY (2004)