Journal
JOURNAL OF FISH DISEASES
Volume 39, Issue 12, Pages 1495-1507Publisher
WILEY-BLACKWELL
DOI: 10.1111/jfd.12487
Keywords
Atlantic salmon calicivirus; cardiomyopathy syndrome; heart and skeletal muscle inflammation; pancreas disease; screening
Funding
- National Research Council of Norway [187301/S40, 216177]
- Fishery and Aquaculture Industry Research Fund [901118]
Ask authors/readers for more resources
Several different viruses have been associated with myocarditis-related diseases in the Atlantic salmon aquaculture industry. In this study, we investigated the presence of PMCV, SAV, PRV and the recently identified Atlantic salmon calicivirus (ASCV), alone and as co-infections in farmed Atlantic salmon displaying myocarditis. The analyses were performed at the individual level and comprised qPCR and histopathological examination of 397 salmon from 25 farms along the Norwegian coast. The samples were collected in 2009 and 2010, 5-22months post-sea transfer. The study documented multiple causes of myocarditis and revealed co-infections including individual fish infected with all four viruses. There was an overall correlation between lesions characteristic of CMS and PD and the presence of PMCV and SAV, respectively. Although PRV was ubiquitously present, high viral loads were with a few exceptions, correlated with lesions characteristic of HSMI. ASCV did not seem to have any impact on myocardial infection by PMCV, SAV or PRV. qPCR indicated a negative correlation between PMCV and SAV viral loads. Co-infections result in mixed and atypical pathological changes which pose a challenge for disease diagnostic work.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available