Maternal and infant outcomes in pregnancies of women with axial spondyloarthritis compared with matched controls: results from nationwide health insurance data

Review Rheumatology

Fertility and pregnancy outcomes in women with spondyloarthritis: a systematic review and meta-analysis

Sabrina Hamroun et al.

Summary: This study found that women with SpA may have a higher risk of preterm birth, small for gestational age, preeclampsia, and caesarean section during pregnancy, without any other unfavorable pregnancy outcomes. Additionally, disease activity in axSpA tends to remain unchanged or worsen during pregnancy, while in PsA it tends to remain unchanged or even improve. Both conditions may flare in the postpartum period.

RHEUMATOLOGY (2022)

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Article Rheumatology

Spondyloarthritis and Outcomes in Pregnancy and Labor: A Nationwide Register-Based Cohort Study

Sofie Mork et al.

Summary: Pregnancies in women with spondyloarthritis were more likely to be complicated by adverse pregnancy outcomes, such as moderately preterm birth, cesarean section, emergency cesarean section, and use of epidural. However, spondyloarthritis was not significantly associated with small for gestational age birth and preeclampsia.

ARTHRITIS CARE & RESEARCH (2021)

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Review Rheumatology

Pregnancy outcomes in women with ankylosing spondylitis: a scoping literature and methodological review

Abir Mokbel et al.

Summary: Key findings of the study include a high percentage of disease flare during pregnancy and postpartum in patients with ankylosing spondylitis (AS), as well as an increased risk of prematurity. However, there was no increased risk of pre-eclampsia across the studies. Cesarean section etiologies were not related to joint issues from AS. The study also highlights the importance of addressing methodological issues and the use of pregnancy registers and validated measurement tools for future research in this field.

CLINICAL RHEUMATOLOGY (2021)

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Review Rheumatology