Journal
FRONTIERS IN NUTRITION
Volume 9, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fnut.2022.901944
Keywords
Camelina sativa L; ultrasound-assisted extraction (USAE); experimental design optimization; human colorectal cancer cell line; recovery bioactive compounds; glucosinolates derivatives; food by-products
Categories
Ask authors/readers for more resources
In this study, glucosinolates were extracted from Camelina sativa seed by-products using a green method based on ultrasound-assisted extraction. The extraction efficiency was optimized, and the extracted glucosinolates showed promising results when tested on human colorectal cancer cell lines.
The food waste generated by small and medium agro-industrial enterprises requires appropriate management and valorization in order to decrease environmental problems and recover high-value products, respectively. In this study, the Camelina sativa seed by-product was used as a source of glucosinolates. To begin, the chemical profile of the extract obtained using an international organization for standardization (ISO) procedure was determined by UPLC-HRMS/MS analysis. In addition, an extraction method based on ultrasound-assisted extraction was developed as an alternative and green method to recover glucosinolates. Main parameters that affect extraction efficiency were optimized using a response surface design. Under optimized conditions, the extract showed an improvement in extraction yield with a reduction in organic solvent amount compared to those obtained using the ISO procedure. Finally, the extract obtained with the ultrasound-assisted method was purified, tested on human colorectal cancer cell lines, and showed promising results.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available