4.3 Article

Spatial expression of the FGFR2b splice isoform and its prognostic significance in endometrioid endometrial carcinoma

Related references

Note: Only part of the references are listed.
Article Oncology

Clinicogenomic Analysis of FGFR2-Rearranged Cholangiocarcinoma Identifies Correlates of Response and Mechanisms of Resistance to Pemigatinib

Ian M. Silverman et al.

Summary: The study utilized genomic profiling data to explore the genomic landscape and molecular diversity of patients with cholangiocarcinoma, as well as analyze the clinicogenomics of patients treated with pemigatinib, highlighting the utility of genomic profiling in clinical trials.

CANCER DISCOVERY (2021)

Article Oncology

Fibroblast Growth Factor Receptor 2 Isoforms Detected via Novel RNA ISH as Predictive Biomarkers for Progestin Therapy in Atypical Hyperplasia and Low-Grade Endometrial Cancer

Asmerom T. Sengal et al.

Summary: The study found that women with AH had a higher response rate to LNG-IUD treatment compared to EEC, and expression of FGFR2c was strongly associated with treatment failure. Further validation in an independent multi-institutional cohort is needed.

CANCERS (2021)

Review Oncology

2b or Not 2b: How Opposing FGF Receptor Splice Variants Are Blocking Progress in Precision Oncology

Richard J. Epstein et al.

Summary: More than ten thousand studies have evaluated the role of FGFs and FGFRs in cancer, with a focus on the complex splicing events of FGFR2 and its isoforms. The ability of FGFR2 to switch between tumor-suppressing and -driving functions based on splicing highlights the need for more specific and precise targeting strategies in cancer treatment.

JOURNAL OF ONCOLOGY (2021)

Article Biochemistry & Molecular Biology

FGF9 and FGF10 activate distinct signaling pathways to direct lung epithelial specification and branching

Yongjun Yin et al.

SCIENCE SIGNALING (2020)

Article Oncology

PORTEC-4a: international randomized trial of molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer

Anne Sophie V. M. van den Heerik et al.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2020)

Article Medicine, General & Internal

Erdafitinib in Locally Advanced or Metastatic Urothelial Carcinoma

Y. Loriot et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Obstetrics & Gynecology

Endometrial stem/progenitor cells and their role in the pathogenesis of endometriosis

Fiona L. Cousins et al.

BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY (2018)

News Item Oncology

BGJ398 for FGFR-altered advanced cholangiocarcinoma

Judith A. Gilbert

LANCET ONCOLOGY (2018)

Review Oncology

Advances and challenges in targeting FGFR signalling in cancer

Irina S. Babina et al.

NATURE REVIEWS CANCER (2017)

Article Oncology

The FGFR Landscape in Cancer: Analysis of 4,853 Tumors by Next-Generation Sequencing

Teresa Helsten et al.

CLINICAL CANCER RESEARCH (2016)

Article Oncology

A clinically applicable molecular-based classification for endometrial cancers

A. Talhouk et al.

BRITISH JOURNAL OF CANCER (2015)

Article Multidisciplinary Sciences

Integrated genomic characterization of endometrial carcinoma

Gad Getz et al.

NATURE (2013)

Article Pathology

FGFR2 alterations in endometrial carcinoma

Sonia Gatius et al.

MODERN PATHOLOGY (2011)

Review Biochemistry & Molecular Biology

Epithelial-Mesenchymal Transitions in Development and Disease

Jean Paul Thiery et al.

Article Biochemistry & Molecular Biology

ESRP1 and ESRP2 Are Epithelial Cell-Type-Specific Regulators of FGFR2 Splicing

Claude C. Warzecha et al.

MOLECULAR CELL (2009)

Article Biochemistry & Molecular Biology

The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development

Richard Grose et al.

EMBO JOURNAL (2007)

Article Gastroenterology & Hepatology

REporting recommendations for tumor MARKer prognostic studies (REMARK)

LM McShane et al.

NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY (2005)

Article Oncology

REporting recommendations for tumor MARKer prognostic studies (REMARK)

LM McShane et al.

NATURE CLINICAL PRACTICE ONCOLOGY (2005)

Article Urology & Nephrology

REporting recommendations for tumor MARKer prognostic studies (REMARK)

LM McShane et al.

NATURE CLINICAL PRACTICE UROLOGY (2005)