Journal
CHEMBIOENG REVIEWS
Volume 9, Issue 5, Pages 442-461Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cben.202100050
Keywords
Antimicrobial; Lauric acid; Monolaurin; Virgin coconut oil
Categories
Funding
- Ministry of Education, Culture, Research, and Technology of Indonesia [249/UN15.19/SP2H/LT/2021]
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Virgin coconut oil, obtained through wet processing, contains high levels of lauric acid, which has antimicrobial properties. It is widely recognized as a healthy food due to its antibacterial, antifungal, and antiviral effects.
Virgin coconut oil is obtained by wet processing of coconut milk using fermentation, centrifugation, enzymatic extraction, and the microwave heating method. Presently, VCO has several positive effects and benefits to human health, hence, it is regularly consumed and widely known as a unique functional food. VCO contains lauric acid (45 to 52 %). By lipase in the digestive system, VCO can undergo a breakdown into lauric acid, 1-monolaurin, and 2-monolaurin. These components have both hydrophilic and lipophilic groups and are also recognized as excellent antimicrobial lipids. Furthermore, lauric acid and monolaurin can be used as antibacterial, antifungal, and antiviral with broad-spectrum inhibition. Lauric acid and monolaurin have a strong ability to destroy gram-positive bacteria, especially S. aureus, fungi such as C. Albicans, and viruses including vesicular stomatitis virus (VSV), herpes simplex virus (HSV), and visna virus (VV). Lauric acid and monolaurin interact with certain functional groups located in the cell membrane and can cause damage to the cell. In general, the potential of VCO as healthy food is contributed by lauric acid and monolaurin which are antimicrobial agents.
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