4.6 Review

Dexamethasone Increases the Anesthetic Success in Patients with Symptomatic Irreversible Pulpitis: A Meta-Analysis

Related references

Note: Only part of the references are listed.
Article Dentistry, Oral Surgery & Medicine

Analgesic effectiveness and safety of celecoxib versus non-opioid active controls after third molar surgery: A meta-analytical evaluation

Mario Alberto Isiordia-Espinoza et al.

Summary: This meta-analysis assessed the analgesic efficacy and adverse effects of celecoxib compared to non-opioid drugs after third molar surgery. The results showed that celecoxib was more effective in pain control and had a lower frequency of nausea and vomiting.

JOURNAL OF STOMATOLOGY ORAL AND MAXILLOFACIAL SURGERY (2022)

Article Dentistry, Oral Surgery & Medicine

Effect of preoperative oral administration of steroids in comparison to an anti-inflammatory drug on postoperative pain following single-visit root canal treatment - a double-blind, randomized clinical trial

N. Suresh et al.

Summary: This study found that preoperative oral administration of a single dose of dexamethasone, piroxicam, or prednisolone can reduce the incidence and severity of postoperative pain following single-visit root canal treatment in patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis up to 24 hours.

INTERNATIONAL ENDODONTIC JOURNAL (2021)

Article Dentistry, Oral Surgery & Medicine

Preoperative Intraligamentary Injection of Dexamethasone Can Improve the Anesthetic Success Rate of 2% Lidocaine during the Endodontic Management of Mandibular Molars with Symptomatic Irreversible Pulpitis

Vivek Aggarwal et al.

Summary: Preoperative administration of dexamethasone intraligamentary injection before endodontic intervention for mandibular molars with symptomatic irreversible pulpitis can increase the success rates of inferior alveolar nerve block with 2% lidocaine.

JOURNAL OF ENDODONTICS (2021)

Article Dentistry, Oral Surgery & Medicine

Evaluating Combined Effect of Oral Premedication with Ibuprofen and Dexamethasone on Success of Inferior Alveolar Nerve Block in Mandibular Molars with Symptomatic Irreversible Pulpitis: A Prospective, Double-blind, Randomized Clinical Trial

Mohit Kumar et al.

Summary: The combination of dexamethasone and ibuprofen improved the success rate of inferior alveolar nerve block in mandibular molars with symptomatic irreversible pulpitis, reducing preoperative pain for patients.

JOURNAL OF ENDODONTICS (2021)

Article Dentistry, Oral Surgery & Medicine

A meta-analysis on the efficacy of the ropivacaine infiltration in comparison with other dental anesthetics

Norma Patricia Figueroa-Fernandez et al.

Summary: The meta-analysis found that ropivacaine has a longer anesthetic time compared to lidocaine/adrenaline and similar anesthesia to bupivacaine. The study suggests that ropivacaine infiltration provides longer anesthesia compared to lidocaine and articaine in dental procedures, but not to bupivacaine.

CLINICAL ORAL INVESTIGATIONS (2021)

Article Materials Science, Biomaterials

Polymer-free hydrogel made of lipid nanocapsules, as a local drug delivery platform

Marion Pitorre et al.

Summary: Nanoparticle-loaded hydrogels combine the advantages of hydrogels and nanoparticles for drug delivery systems. Novel lipid nanocapsule-based hydrogels show promise as implants for pharmaceutical applications due to their controlled drug-release profiles and reduced toxicity.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Article Biochemistry & Molecular Biology

Chitosan Membranes Filled with Cyclosporine A as Possible Devices for Local Administration of Drugs in the Treatment of Breast Cancer

Sonia Trombino et al.

Summary: This study aimed at designing, preparing, and characterizing membranes based on CsA and CC for the treatment of breast cancer, showing successful formation of amide bond between CsA and CC and complete dispersion of CsA in the polymeric membrane. Preliminary tests demonstrated a significant inhibition of cancer cell proliferation with the membranes.

MOLECULES (2021)

Review Chemistry, Medicinal

A Meta-Analysis of the Analgesic Efficacy of Single-Doses of Ibuprofen Compared to Traditional Non-Opioid Analgesics Following Third Molar Surgery

Lorenzo Franco-de La Torre et al.

Summary: This systematic review suggests that ibuprofen is more effective for relieving post-operative dental pain after third molar surgery compared to other traditional non-opioid analgesics, with a similar safety profile.

PHARMACEUTICALS (2021)

Review Pharmacology & Pharmacy

Women-specific routes of administration for drugs: A critical overview

Jose das Neves et al.

Summary: The female body presents unique anatomical features that can be utilized as valuable routes for drug administration. Understanding the possibilities and limitations of women-specific routes is crucial for the development of new therapeutic strategies that will contribute to the advancement of women's health. This article provides an overview on women-specific routes for drug administration, focusing on biological features, clinical relevance, available drug dosage forms/delivery systems, administration techniques, and recent trends in the field.

ADVANCED DRUG DELIVERY REVIEWS (2021)

Article Dentistry, Oral Surgery & Medicine

The effect of pre-operative submucosal administration of dexamethasone, tramadol, articaine on the success rate of inferior alveolar nerve block on mandibular molars with symptomatic irreversible pulpitis: A randomized, double-blind placebo-controlled clinical trial

Fatih Aksoy et al.

Summary: The study showed that administration of tramadol, dexamethasone, and articaine during root canal treatment of mandibular molars with symptomatic irreversible pulpitis can increase the success rate of anesthesia and prolong its duration, especially with submucosal administration of articaine.

INTERNATIONAL ENDODONTIC JOURNAL (2021)

Article Pharmacology & Pharmacy

Local administration of ReveromycinA ointment suppressed alveolar bone loss in mice

Ken Miyazawa et al.

Summary: The study demonstrated that localized application of RMA-containing ointment in the oral cavity effectively suppressed alveolar bone resorption in periodontitis.

JOURNAL OF PHARMACOLOGICAL SCIENCES (2021)

Review Infectious Diseases

Potential Adverse Effects of Dexamethasone Therapy on COVID-19 Patients: Review and Recommendations

Fei Chen et al.

Summary: Dexamethasone is the first and crucial therapeutic agent that significantly reduces the risk of death in severe COVID-19 patients, alleviating SARS-CoV-2-induced complications but also posing significant adverse effects later in life. While necessary for critical patients, its potential harms cannot be overlooked, necessitating further research and clinical trials.

INFECTIOUS DISEASES AND THERAPY (2021)

Review Dentistry, Oral Surgery & Medicine

Glossary for systematic reviews and meta-analyses

V Nagendrababu et al.

INTERNATIONAL ENDODONTIC JOURNAL (2020)

Article Dentistry, Oral Surgery & Medicine

Intraoral Somatosensory Alterations Impact Pulp Sensibility Testing in Patients with Symptomatic Irreversible Pulpitis

Yuri M. Costa et al.

JOURNAL OF ENDODONTICS (2020)

Review Dentistry, Oral Surgery & Medicine

Is the Use of Dexamethasone Effective in Controlling Pain Associated with Symptomatic Irreversible Pulpitis? A Systematic Review

Brenna M. L. Nogueira et al.

JOURNAL OF ENDODONTICS (2018)

Article Health Care Sciences & Services

Evaluating the quality of medical evidence in real-world contexts

Andrew Jones et al.

JOURNAL OF EVALUATION IN CLINICAL PRACTICE (2018)

Article Dentistry, Oral Surgery & Medicine

Successful pulpal anesthesia for symptomatic irreversible pulpitis

Melissa Drum et al.

JOURNAL OF THE AMERICAN DENTAL ASSOCIATION (2017)

Review Medicine, General & Internal

Dexamethasone as an adjuvant to peripheral nerve block

Carolyne Pehora et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2017)

Article Dentistry, Oral Surgery & Medicine

Submucous tramadol increases the anesthetic efficacy of mepivacaine with epinephrine in inferior alveolar nerve block

Mario Alberto Isiordia-Espinoza et al.

BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY (2012)

Article Pharmacology & Pharmacy

Strategies and Therapeutic Opportunities for the Delivery of Drugs to the Esophagus

Liang Zhang et al.

CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS (2012)

Article Dentistry, Oral Surgery & Medicine

Preemptive analgesic effectiveness of oral ketorolac plus local tramadol after impacted mandibular third molar surgery

Mario A. Isiordia-Espinoza et al.

MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL (2011)

Article Clinical Neurology

Sodium Channel Expression and Localization at Demyelinated Sites in Painful Human Dental Pulp

Michael A. Henry et al.

JOURNAL OF PAIN (2009)

Article Dentistry, Oral Surgery & Medicine

Effect of supraperiosteal injection of dexamethasone on postoperative pain

Payman Mehrvarzfar et al.

AUSTRALIAN ENDODONTIC JOURNAL (2008)

Article Dentistry, Oral Surgery & Medicine

Effect of pulp inflammation on nerve impulse quality with or without anesthesia

Jalil Modaresi et al.

JOURNAL OF ENDODONTICS (2008)

Article Medicine, General & Internal

Measuring inconsistency in meta-analyses

JPT Higgins et al.

BMJ-BRITISH MEDICAL JOURNAL (2003)