Journal
ESMO OPEN
Volume 7, Issue 4, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.esmoop.2022.100524
Keywords
next-generation sequencing (NGS); metastatic tumors; genomic alterations; genomic-driven therapy; molecular tumor board
Categories
Funding
- Belgian Foundation against Cancer and Kom op Tegen Kanker
- Roche
- Illumina
- OncoDNA
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The PRECISION initiative by the Belgian Society of Medical Oncology aims to enhance genomic and clinical knowledge for patients with metastatic solid tumors through molecularly guided treatments. It consists of four programs, including the creation of a clinico-genomic database, extensive tumor testing, and investigator-initiated clinical studies.
PRECISION is an initiative from the Belgian Society of Medical Oncology (BSMO) in collaboration with several stakeholders, encompassing four programs that aim to boost genomic and clinical knowledge with the ultimate goal to offer patients with metastatic solid tumors molecularly guided treatments. The PRECISION 1 study has led to the creation of a clinico-genomic database. The Belgian Approach for Local Laboratory Extensive Tumor Testing (BALLETT) and GeNeo studies will increase the number of patients with advanced cancer that have comprehensive genotyping of their cancer. The PRECISION 2 project consists of investigator-initiated phase II studies aiming to provide access to a targeted drug for patients whose tumors harbor actionable mutations in case the matched drug is not available through reimbursement or clinical trials in Belgium.
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