Journal
GENERAL THORACIC AND CARDIOVASCULAR SURGERY
Volume 70, Issue 10, Pages 924-929Publisher
SPRINGER JAPAN KK
DOI: 10.1007/s11748-022-01859-7
Keywords
Esophageal cancer; Lymph node metastasis; Near-infrared fluorescence image; Indocyanine green
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This study presents a novel NIR-guided surgical technique for predicting lymph node metastasis in esophageal cancer patients with high diagnostic accuracy, achieved by adjusting the ICG injection setting appropriately.
Lymphatic flow mapping using near-infrared fluorescence (NIR) imaging with indocyanine green (ICG) has been used for intraoperative diagnosis of lymph node metastasis (LNM) in various cancers. Accurate prediction of LNM intraoperatively may allow minimization of the extent of lymphadenectomy. However, a consistent method and diagnostic ability, allowing application of NIR-guided lymphatic flow mapping to esophageal cancer (EC), have not been established due to the multidirectional and complex characteristics of lymphatic flow in the esophagus. Herein, we present a novel NIR-guided surgical technique for predicting lymph node stations potentially containing LNM in EC with high diagnostic accuracy derived from appropriately adjusting the ICG injection setting.
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