Journal
MATERIALS TODAY COMMUNICATIONS
Volume 32, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.mtcomm.2022.104068
Keywords
Carbon quantum dots; Bioimaging; Cancer targeting; Drug delivery; In vivo imaging
Categories
Funding
- Indian Council of Medical Research (ICMR) , New Delhi, India [5/3/8/26/ITR-F/2022]
Ask authors/readers for more resources
Carbon quantum dots have shown great potential in simultaneous bioimaging and drug delivery for cancer treatment due to their excellent properties. This review provides a comprehensive discussion on synthesis methods, modifications, optical properties, and characterization techniques of carbon dots. The applications of carbon dots in cancer therapy, including targeted drug delivery and real-time monitoring through fluorescence imaging, are also explored. Furthermore, potential strategies for overcoming challenges in cancer chemotherapy and future prospects in the development of carbon dots-based nano-theranostics are discussed.
Recently, carbon quantum dots have emerged as a promising nanomaterial for simultaneous bioimaging and drug delivery in cancer due to their excellent properties like fluorescence emission, good photostability, high water solubility, good biocompatibility, small size, ease in surface functionalization and low toxicity. The current review discusses the different synthetic routes, post synthesis modifications, optical properties and character-ization techniques for carbon dots. Further, problems associated with cancer chemotherapy and the potential nanomaterial-based strategies to overcome it, have been highlighted. Besides, the recent progress in the domain of carbon dots-based strategies in anticancer drug delivery and real time monitoring through fluorescence im-aging are also discussed. In continuation, approaches like carbon dots based active and passive targeting, tumor microenvironment targeting, multifunctional targeting, etc. are elaborated. Carbon dots applications for in vivo imaging and biodistributions in cancer models are also collectively presented. Finally, critical opinions and future scopes in the development of carbon dots based advanced nano-theranostics in cancer treatment are discussed. The current review can offer broader vision and a sound roadmap to the researchers working in the domain of cancer nano-theranostics and cancer targeted drug delivery.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available