4.6 Article

The Impact of Hidden Structure on Aggregate Disassembly by Molecular Chaperones

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Protein Aggregation and Disaggregation in Cells and Development

Jan S. Fassler et al.

Summary: Protein aggregation is a characteristic of many neurodegenerative diseases, but it can also regulate cellular activities such as stress response, gene expression, and cell development. This review explores examples of protein aggregates in biological systems and cellular strategies for controlling aggregation and disassembly.

JOURNAL OF MOLECULAR BIOLOGY (2021)

Article Biophysics

Development and application of multicolor burst analysis spectroscopy

Daniel Shoup et al.

Summary: The development of multicolor BAS provides a powerful and flexible approach to studying hidden properties of important biological particles like viruses and protein aggregates.

BIOPHYSICAL JOURNAL (2021)

Article Multidisciplinary Sciences

Processive extrusion of polypeptide loops by a Hsp100 disaggregase

Mario J. Avellaneda et al.

NATURE (2020)

Article Multidisciplinary Sciences

Bacterial Hsp70 resolves misfolded states and accelerates productive folding of a multi-domain protein

Rahmi Imamoglu et al.

NATURE COMMUNICATIONS (2020)

Review Biochemistry & Molecular Biology

Recent advances in understanding catalysis of protein folding by molecular chaperones

David Balchin et al.

FEBS LETTERS (2020)

Review Biochemistry & Molecular Biology

Hsp70-mediated quality control: should I stay or should I go?

Verena Kohler et al.

BIOLOGICAL CHEMISTRY (2020)

Article Multidisciplinary Sciences

HSP40 proteins use class-specific regulation to drive HSP70 functional diversity

Ofrah Faust et al.

NATURE (2020)

Article Cell Biology

Spiraling in Control: Structures and Mechanisms of the Hsp104 Disaggregase

James Shorter et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2019)

Review Cell Biology

The Hsp70 chaperone network

Rina Rosenzweig et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)

Review Biochemistry & Molecular Biology

Cellular Handling of Protein Aggregates by Disaggregation Machines

Axel Mogk et al.

MOLECULAR CELL (2018)

Review Biochemistry & Molecular Biology

Protein Disaggregation in Multicellular Organisms

Nadinath B. Nillegoda et al.

TRENDS IN BIOCHEMICAL SCIENCES (2018)

Article Multidisciplinary Sciences

Ratchet-like polypeptide translocation mechanism of the AAA plus disaggregase Hsp104

Stephanie N. Gates et al.

SCIENCE (2017)

Article Multidisciplinary Sciences

Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase

Celia Deville et al.

SCIENCE ADVANCES (2017)

Article Biochemistry & Molecular Biology

Clathrin-coat disassembly illuminates the mechanisms of Hsp70 force generation

Rui Sousa et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Clathrin-coat disassembly illuminates the mechanisms of Hsp70 force generation

Rui Sousa et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)

Review Biochemistry & Molecular Biology

The Biology of Proteostasis in Aging and Disease

Johnathan Labbadia et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)

Article Multidisciplinary Sciences

Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation

Nadinath B. Nillegoda et al.

NATURE (2015)

Article Multidisciplinary Sciences

Single-molecule spectroscopy reveals chaperone-mediated expansion of substrate protein

Ruth Kellner et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

Rina Rosenzweig et al.

SCIENCE (2013)

Article Biochemistry & Molecular Biology

Molecular chaperones DnaK and DnaJ share predicted binding sites on most proteins in the E. coli proteome

Sharan R. Srinivasan et al.

MOLECULAR BIOSYSTEMS (2012)

Article Biochemistry & Molecular Biology

Hsp70 proteins bind Hsp100 regulatory M domains to activate AAA plus disaggregase at aggregate surfaces

Fabian Seyffer et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)

Article Biochemistry & Molecular Biology

A tightly regulated molecular toggle controls AAA plus disaggregase

Yuki Oguchi et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)

Article Biochemistry & Molecular Biology

The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of L-phenylalanine and its derivatives

Yane-Shih Wang et al.

MOLECULAR BIOSYSTEMS (2011)

Review Multidisciplinary Sciences

Molecular chaperones in protein folding and proteostasis

F. Ulrich Hartl et al.

NATURE (2011)

Article Multidisciplinary Sciences

Species-specific collaboration of heat shock proteins (Hsp) 70 and 100 in thermotolerance and protein disaggregation

Marika Miot et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Purification of Hsp104, a Protein Disaggregase

Elizabeth A. Sweeny et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2011)

Article Biochemistry & Molecular Biology

The M-Domain Controls Hsp104 Protein Remodeling Activity in an Hsp70/Hsp40-Dependent Manner

Bernhard Sielaff et al.

JOURNAL OF MOLECULAR BIOLOGY (2010)

Review Cell Biology

`The HSP70 chaperone machinery: J proteins as drivers of functional specificity

Harm H. Kampinga et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

DnaK-mediated association of ClpB to protein aggregates. A bichaperone network at the aggregate surface

Sergio P. Acebron et al.

FEBS LETTERS (2009)

Review Biochemistry & Molecular Biology

Biology, one molecule at a time

Achillefs N. Kapanidis et al.

TRENDS IN BIOCHEMICAL SCIENCES (2009)

Article Biochemical Research Methods

Accurate Prediction of DnaK-Peptide Binding via Homology Modelling and Experimental Data

Joost Van Durme et al.

PLOS COMPUTATIONAL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Protein disaggregation by the AAA plus chaperone ClpB involves partial threading of looped polypeptide segments

Tobias Haslberger et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)

Article Biochemistry & Molecular Biology

GroEL stimulates protein folding through forced unfolding

Zong Lin et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)

Article Multidisciplinary Sciences

Burst analysis spectroscopy: A versatile single-particle approach for studying distributions of protein aggregates and fluorescent assemblies

Jason Puchalla et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Multidisciplinary Sciences

Adapting proteostasis for disease intervention

William E. Balch et al.

SCIENCE (2008)

Article Multidisciplinary Sciences

Hsp70 chaperones accelerate protein translocation and the unfolding of stable protein aggregates by entropic pulling

P De los Rios et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Active solubilization and refolding of stable protein aggregates by cooperative unfolding action of individual Hsp70 chaperones

A Ben-Zvi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Expansion and compression of a protein folding intermediate by GroEL

Z Lin et al.

MOLECULAR CELL (2004)