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Advanced Molecular and Immunological Diagnostic Methods to Detect SARS-CoV-2 Infection

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Thrombotic Adverse Events Reported for Moderna, Pfizer and Oxford-AstraZeneca COVID-19 Vaccines: Comparison of Occurrence and Clinical Outcomes in the EudraVigilance Database

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A Comparative Study of Real-Time RT-PCReBased SARS-CoV-2 Detection Methods and Its Application to Human-Derived and Surface Swabbed Material

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Protective Role of Combined Polyphenols and Micronutrients against Influenza A Virus and SARS-CoV-2 Infection In Vitro

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Clinical Relevance of Elevated Soluble ST2, HSP27 and 20S Proteasome at Hospital Admission in Patients with COVID-19

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Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2-ACE2 Interactions

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Summary: This study identified compounds that bind to human ACE2 or the SARS-CoV-2 spike protein receptor binding domain through molecular docking and SPR screening, with three compounds demonstrating dose-dependent antiviral potency in vitro.

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Methylation of SERPINA1 gene promoter may predict chronic obstructive pulmonary disease in patients affected by acute coronary syndrome

John Charles Rotondo et al.

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Nucleic Acid Testing of SARS-CoV-2

Hee Min Yoo et al.

Summary: This review discusses the importance of accuracy and sensitivity in COVID-19 diagnosis, highlighting various detection methods such as PCR, digital PCR, and RT-LAMP. Non-conventional molecular diagnostic methods like NGS, CRISPR technology, and nanotechnology are also improving the accuracy of COVID-19 testing. Additionally, the standardization of SARS-CoV-2 nucleic acid testing and the use of reference materials as resources are emphasized.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection

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Summary: This study conducted a paired analysis of nasopharyngeal and systemic immune responses in COVID-19 patients, revealing distinct compartmentalization of immunity and shifts in the microbiome.

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Review Biochemistry & Molecular Biology

The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology

Bas B. Oude Munnink et al.

Summary: This review summarizes the current knowledge on key viral mutations and variants, emphasizing the need for a systematic approach to link global genomic surveillance with timely assessment of the phenotypic characteristics of novel variants in preparation for the next phase of the pandemic.

NATURE MEDICINE (2021)

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Review Virology

SARS-CoV-2 Infection: New Molecular, Phylogenetic, and Pathogenetic Insights. Efficacy of Current Vaccines and the Potential Risk of Variants

John Charles Rotondo et al.

Summary: SARS-CoV-2 has caused the COVID-19 pandemic, leading to significant global health concerns. Despite scientific advancements, understanding of the virus remains limited. The development and deployment of vaccines has shown positive effects, but the emergence of new variants poses challenges to controlling and eradicating the infection.

VIRUSES-BASEL (2021)

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Article Microbiology

Oral Microbiome Dysbiosis Is Associated With Symptoms Severity and Local Immune/Inflammatory Response in COVID-19 Patients: A Cross-Sectional Study

Irene Soffritti et al.

Summary: The study revealed that oral dysbiosis in COVID-19 patients is associated with symptom severity and increased local inflammation, while a decreased mucosal immune response was also observed. The characteristics of the HOM may play a significant role in defining individual susceptibility to SARS-CoV-2 infection.

FRONTIERS IN MICROBIOLOGY (2021)

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Article Oncology

Responses to SARS-CoV-2 Vaccination in Patients with Cancer (ReCOVer Study): A Prospective Cohort Study of the Hellenic Cooperative Oncology Group

Helena Linardou et al.

Summary: In cancer patients, despite a high seropositivity rate after receiving two vaccine doses, their antibody titers were significantly lower compared to healthy controls. Monitoring immune responses and understanding clinical factors influencing immunity could aid in adjusting vaccination strategies for vulnerable subgroups.

CANCERS (2021)

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Review Cell Biology

Epigenetics of Male Infertility: The Role of DNA Methylation

John Charles Rotondo et al.

Summary: Research has shown a correlation between sperm DNA methylation and male infertility, with various genes displaying differential methylation patterns in impaired spermatogenesis and reproductive dysfunction. Specifically, DNA methylation defects in MEST and H19 within imprinted genes, as well as MTHFR within non-imprinted genes, have been linked to male infertility. Further studies are needed to better understand the mechanisms affecting methylation in sperm and its impact on male infertility.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

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Review Biochemistry & Molecular Biology

Evaluation and Comparison of Serological Methods for COVID-19 Diagnosis

Fanwu Gong et al.

Summary: The global COVID-19 pandemic has led to the development of various clinical diagnosis methods, including nucleic acid testing and serological screening. Due to the unsatisfactory sensitivity of nucleic acid detection, serological screening has become widely used. These serological diagnostic methods help improve clinical efficiency and control the spread of COVID-19.

FRONTIERS IN MOLECULAR BIOSCIENCES (2021)

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Article Multidisciplinary Sciences

Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2

Xingyue An et al.

Summary: The development of an intranasal subunit vaccine that induces mucosal immunity in the respiratory tract has been reported, demonstrating the potential to prevent infection establishment in individuals and disease transmission.

ISCIENCE (2021)

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Review Chemistry, Analytical

Molecular diagnostics in the era of COVID-19

Harindi Jayakody et al.

Summary: The review discusses the application of molecular diagnostic technologies in controlling the spread of COVID-19 and the key factors affecting the sensitivity and specificity of the tests used.

ANALYTICAL METHODS (2021)

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Review Medicine, General & Internal

Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection

Jacqueline Dinnes et al.

Summary: Accurate and rapid diagnostic tests for SARS-CoV-2 infection are crucial for managing the COVID-19 pandemic. Point-of-care antigen and molecular tests can increase access to testing and expedite clinical and public health management decisions. Studies show that antigen tests have varying sensitivity, with higher accuracy in the first week of infection, and the efficacy of molecular tests depends on the specific brand used.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2021)

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Article Ophthalmology

Evaluation of Anti-SARS-CoV-2 IgA in the Conjunctival Secretions of COVID-19 Patients

Hany Mahmoud et al.

Summary: The study found that anti-SARS-CoV-2 IgA can be detected in ocular secretions of SARS-CoV-2 patients, with no correlation to age, sex, or disease severity, but a correlation with ocular symptoms.

CLINICAL OPHTHALMOLOGY (2021)

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Article Medicine, General & Internal

Non-Respiratory Symptoms of Patients Infected with SARS-CoV-2 (Coronavirus Disease 2019): Lessons from Their Initial Presentation at the Hospital

Angelo V. Vasiliadis et al.

Summary: The study aimed to describe non-respiratory symptoms of laboratory-confirmed COVID-19 cases. It found that musculoskeletal symptoms such as fatigue, myalgia, and arthralgia were present in three-quarters of patients at symptom onset. These findings could aid in developing updated triage and admission protocols for suspected COVID-19 patients.

MEDICINA-LITHUANIA (2021)

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Article Microbiology

Analytical Sensitivity of the Abbott BinaxNOW COVID-19 Ag Card

Garrett A. Perchetti et al.

Summary: This study evaluated the analytical sensitivity of the Abbott BinaxNOW COVID-19 Ag card, finding detection limits of approximately 4.04 x 10(4) to 8.06 x 10(4) copies/swab, and good detection performance for samples with SARS-CoV-2 viral loads above 40,000 copies/swab.

JOURNAL OF CLINICAL MICROBIOLOGY (2021)

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Article Immunology

Next Generation Sequencing and Bioinformatics Methodologies for Infectious Disease Research and Public Health: Approaches, Applications, and Considerations for Development of Laboratory Capacity

Irina Maljkovic Berry et al.

JOURNAL OF INFECTIOUS DISEASES (2020)

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Article Infectious Diseases

Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR

Victor M. Corman et al.

EUROSURVEILLANCE (2020)

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Article Virology

Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis

Zhengtu Li et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

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Article Multidisciplinary Sciences

A new coronavirus associated with human respiratory disease in China

Fan Wu et al.

NATURE (2020)

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Letter Medicine, General & Internal

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

Lirong Zou et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Letter Medicine, General & Internal

Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany

Camilla Rothe et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Medicine, General & Internal

A Novel Coronavirus from Patients with Pneumonia in China, 2019

Na Zhu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Microbiology

Metagenomic sequencing with spiked primer enrichment for viral diagnostics and genomic surveillance

Xianding Deng et al.

NATURE MICROBIOLOGY (2020)

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Review Pharmacology & Pharmacy

Recent advances and perspectives of nucleic acid detection for coronavirus

Minzhe Shen et al.

JOURNAL OF PHARMACEUTICAL ANALYSIS (2020)

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Article Biochemical Research Methods

VADR: validation and annotation of virus sequence submissions to GenBank

Alejandro A. Schaffer et al.

BMC BIOINFORMATICS (2020)

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Article Biochemistry & Molecular Biology

The Architecture of SARS-CoV-2 Transcriptome

Dongwan Kim et al.

CELL (2020)

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Article Immunology

Quantitative Detection and Viral Load Analysis of SARS-CoV-2 in Infected Patients

Fengting Yu et al.

CLINICAL INFECTIOUS DISEASES (2020)

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Editorial Material Biochemistry & Molecular Biology

Could Intravenous Immunoglobulin Collected from Recovered Coronavirus Patients Protect against COVID-19 and Strengthen the Immune System of New Patients?

Samir Jawhara

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Review Biochemical Research Methods

Nucleic Acid Detection Using CRISPR/Cas Biosensing Technologies

Rashid Aman et al.

ACS SYNTHETIC BIOLOGY (2020)

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Article Oncology

Role of human papillomavirus infection in the etiology of vulvar cancer in Italian women

Mario Preti et al.

INFECTIOUS AGENTS AND CANCER (2020)

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Article Immunology

ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens

Tao Suo et al.

EMERGING MICROBES & INFECTIONS (2020)

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Article Chemistry, Multidisciplinary

Assay Techniques and Test Development for COVID-19 Diagnosis

Linda J. Carter et al.

ACS CENTRAL SCIENCE (2020)

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Article Biotechnology & Applied Microbiology

CRISPR-Cas12-based detection of SARS-CoV-2

James P. Broughton et al.

NATURE BIOTECHNOLOGY (2020)

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Letter Cell Biology

Single-copy sensitive, field-deployable, and simultaneous dual-gene detection of SARS-CoV-2 RNA via modified RT-RPA

Simin Xia et al.

CELL DISCOVERY (2020)

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Article Microbiology

High Human Papillomavirus DNA loads in Inflammatory Middle Ear Diseases

Nicola Malagutti et al.

PATHOGENS (2020)

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Article Medical Laboratory Technology

Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020

Rui Liu et al.

CLINICA CHIMICA ACTA (2020)

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Article Infectious Diseases

Comparison of diagnostic accuracies of rapid serological tests and ELISA to molecular diagnostics in patients with suspected coronavirus disease 2019 presenting to the hospital

D. S. Y. Ong et al.

CLINICAL MICROBIOLOGY AND INFECTION (2020)

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Article Microbiology

Lower cost alternatives for molecular diagnosis of COVID-19: conventional RT-PCR and SYBR Green-based RT-qPCR

Erick Gustavo Dorlass et al.

BRAZILIAN JOURNAL OF MICROBIOLOGY (2020)

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Article Chemistry, Medicinal

Comparative Analysis of Primer-Probe Sets for RT-qPCR of COVID-19 Causative Virus (SARS-CoV-2)

Yujin Jung et al.

ACS INFECTIOUS DISEASES (2020)

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Review Multidisciplinary Sciences

Molecular diagnostic technologies for COVID-19: Limitations and challenges

Adeel Afzal

JOURNAL OF ADVANCED RESEARCH (2020)

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Review Pharmacology & Pharmacy

Synthetic Virus-Derived Nanosystems (SVNs) for Delivery and Precision Docking of Large Multifunctional DNA Circuitry in Mammalian Cells

Francesco Aulicino et al.

PHARMACEUTICS (2020)

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Article Virology

Assessment of SARS-CoV-2 serological tests for the diagnosis of COVID-19 through the evaluation of three immunoassays: Two automated immunoassays (Euroimmun and Abbott) and one rapid lateral flow immunoassay (NG Biotech)

Thomas Nicol et al.

JOURNAL OF CLINICAL VIROLOGY (2020)

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Article Virology

Comparison of commercial lateral flow immunoassays and ELISA for SARS-CoV-2 antibody detection

Maria Martinez Serrano et al.

JOURNAL OF CLINICAL VIROLOGY (2020)

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Review Microbiology

COVID-19 Is a Multifaceted Challenging Pandemic Which Needs Urgent Public Health Interventions

Carlo Contini et al.

MICROORGANISMS (2020)

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Article Biochemistry & Molecular Biology

Immune Phenotyping Based on the Neutrophil-to-Lymphocyte Ratio and IgG Level Predicts Disease Severity and Outcome for Patients With COVID-19

Bicheng Zhang et al.

FRONTIERS IN MOLECULAR BIOSCIENCES (2020)

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Review Multidisciplinary Sciences

Molecular and Immunological Diagnostic Tests of COVID-19: Current Status and Challenges

Tugba Kilic et al.

ISCIENCE (2020)

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Review Pediatrics

Multi-System Inflammatory Syndrome in Children (MIS-C) Following SARS-CoV-2 Infection: Review of Clinical Presentation, Hypothetical Pathogenesis, and Proposed Management

Natasha A. Nakra et al.

CHILDREN-BASEL (2020)

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Letter Infectious Diseases

SARS-CoV-2 RNA more readily detected in induced sputum than in throat swabs of convalescent COVID-19 patients

Huanqin Han et al.

LANCET INFECTIOUS DISEASES (2020)

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Article Infectious Diseases

Serology testing in the COVID-19 pandemic response

Rosanna W. Peeling et al.

LANCET INFECTIOUS DISEASES (2020)

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Article Chemistry, Multidisciplinary

Nanopore Targeted Sequencing for the Accurate and Comprehensive Detection of SARS-CoV-2 and Other Respiratory Viruses

Ming Wang et al.

SMALL (2020)

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Article Cell Biology

Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections

Huibin Lv et al.

CELL REPORTS (2020)

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Article Genetics & Heredity

Multiple approaches for massively parallel sequencing of SARS-CoV-2 genomes directly from clinical samples

Minfeng Xiao et al.

GENOME MEDICINE (2020)

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Letter Dermatology

Tissue cytokine/chemokine profile in vulvar lichen sclerosus: An observational study on keratinocyte and fibroblast cultures

Monica Corazza et al.

JOURNAL OF DERMATOLOGICAL SCIENCE (2020)

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Article Multidisciplinary Sciences

Rapid isothermal amplification and portable detection system for SARS-CoV-2

Anurup Ganguli et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

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Review Biochemical Research Methods

Isothermal SARS-CoV-2 Diagnostics: Tools for Enabling Distributed Pandemic Testing as a Means of Supporting Safe Reopenings

Pavana Khan et al.

ACS SYNTHETIC BIOLOGY (2020)

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Editorial Material Medicine, General & Internal

Are we underestimating seroprevalence of SARS-CoV-2? Current antibody tests fail to identify people who had mild infections

Stephen Burgess et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

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Article Microbiology

Development and evaluation of a rapid CRISPR-based diagnostic for COVID-19

Tieying Hou et al.

PLOS PATHOGENS (2020)

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Article Cell & Tissue Engineering

Canonical Wnt Pathway Controls mESC Self-Renewal Through Inhibition of Spontaneous Differentiation via β-Catenin/TCF/LEF Functions

Francesco Aulicino et al.

STEM CELL REPORTS (2020)

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Review Immunology

Current Understanding of Natural Antibodies and Exploring the Possibilities of Modulation Using Veterinary Models. A Review

G. IJsbrand Reyneveld et al.

FRONTIERS IN IMMUNOLOGY (2020)

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Article Health Policy & Services

COVID-19 pandemic in the United States

Savannah Bergquist et al.

HEALTH POLICY AND TECHNOLOGY (2020)

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Review Medicine, General & Internal

Rapid Antibody-Based COVID-19 Mass Surveillance: Relevance, Challenges, and Prospects in a Pandemic and Post-Pandemic World

Robin Augustine et al.

JOURNAL OF CLINICAL MEDICINE (2020)

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Article Cell Biology

SERPINA1 Gene Promoter Is Differentially Methylated in Peripheral Blood Mononuclear Cells of Pregnant Women

John Charles Rotondo et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

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Article Immunology

Investigation on Spontaneous Abortion and Human Papillomavirus Infection

Mauro Tognon et al.

VACCINES (2020)

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Article Microbiology

In silico Investigation on the Inhibiting Role of Nicotine/Caffeine by Blocking the S Protein of SARS-CoV-2 Versus ACE2 Receptor

Saeedeh Mohammadi et al.

MICROORGANISMS (2020)

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Article Public, Environmental & Occupational Health

SARS-CoV-2 Infections in the World: An Estimation of the Infected Population and a Measure of How Higher Detection Rates Save Lives

Carlos Villalobos

FRONTIERS IN PUBLIC HEALTH (2020)

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Article Multidisciplinary Sciences

Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2

Jon Arizti-Sanz et al.

NATURE COMMUNICATIONS (2020)

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Review Multidisciplinary Sciences

The diagnostic accuracy of isothermal nucleic acid point-of-care tests for human coronaviruses: A systematic review and meta-analysis

Pakpoom Subsoontorn et al.

SCIENTIFIC REPORTS (2020)

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Article Microbiology

Simultaneous Detection and Viral DNA Load Quantification of Different Human Papillomavirus Types in Clinical Specimens by the High Analytical Droplet Digital PCR Method

John Charles Rotondo et al.

FRONTIERS IN MICROBIOLOGY (2020)

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Article Immunology

Mucosal Immunity in COVID-19: A Neglected but Critical Aspect of SARS-CoV-2 Infection

Michael W. Russell et al.

FRONTIERS IN IMMUNOLOGY (2020)

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Article Biology

Anti-SARS-Cov-2 IgA Response in Tears of COVID-19 Patients

Elisabetta Caselli et al.

BIOLOGY-BASEL (2020)

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Article Immunology

Serological detection of 2019-nCoV respond to the epidemic: A useful complement to nucleic acid testing

Jin Zhang et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2020)

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Article Immunology

Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibody Responses in Coronavirus Disease Patients

Nisreen M. A. Okba et al.

EMERGING INFECTIOUS DISEASES (2020)

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Review Biotechnology & Applied Microbiology

Opportunities and challenges in long-read sequencing data analysis

Shanika L. Amarasinghe et al.

GENOME BIOLOGY (2020)

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Article Immunology

Establishment and validation of a pseudovirus neutralization assay for SARS-CoV-2

Jianhui Nie et al.

EMERGING MICROBES & INFECTIONS (2020)

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Review Immunology

Laboratory diagnosis of emerging human coronavirus infections - the state of the art

Michael J. Loeffelholz et al.

EMERGING MICROBES & INFECTIONS (2020)

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Article Immunology

Lack of cross-neutralization by SARS patient sera towards SARS-CoV-2

Danielle E. Anderson et al.

EMERGING MICROBES & INFECTIONS (2020)

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Article Cell Biology

Investigation on silent bacterial infections in specimens from pregnant women affected by spontaneous miscarriage

Carlo Contini et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

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Article Multidisciplinary Sciences

Wnt/β-catenin signaling pathway safeguards epigenetic stability and homeostasis of mouse embryonic stem cells

Ilda Theka et al.

SCIENTIFIC REPORTS (2019)

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Article Biochemical Research Methods

SHERLOCK: nucleic acid detection with CRISPR nucleases

Max J. Kellner et al.

NATURE PROTOCOLS (2019)

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Review Biotechnology & Applied Microbiology

CRISPR/Cas Systems towards Next-Generation Biosensing

Yi Li et al.

TRENDS IN BIOTECHNOLOGY (2019)

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Review Infectious Diseases

Next-generation sequencing technologies and their application to the study and control of bacterial infections

J. Besser et al.

CLINICAL MICROBIOLOGY AND INFECTION (2018)

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Article Environmental Sciences

Environmental doses of perfluorooctanoic acid change the expression of genes in target tissues of common carp

John Charles Rotondo et al.

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2018)

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Article Multidisciplinary Sciences

Field-deployable viral diagnostics using CRISPR-Cas13

Cameron Myhrvold et al.

SCIENCE (2018)

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Article Multidisciplinary Sciences

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

Janice S. Chen et al.

SCIENCE (2018)

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Editorial Material Multidisciplinary Sciences

Next-generation diagnostics with CRISPR

Daniel S. Chertow

SCIENCE (2018)

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Article Multidisciplinary Sciences

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

Jonathan S. Gootenberg et al.

SCIENCE (2018)

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Review Microbiology

Clinical and biological insights from viral genome sequencing

Charlotte J. Houldcroft et al.

NATURE REVIEWS MICROBIOLOGY (2017)

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Article Multidisciplinary Sciences

Application of droplet digital PCR for quantitative detection of Spiroplasma citri in comparison with real time PCR

Yogita Maheshwari et al.

PLOS ONE (2017)

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Article Multidisciplinary Sciences

Nucleic acid detection with CRISPR-Cas13a/C2c2

Jonathan S. Gootenberg et al.

SCIENCE (2017)

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Review Immunology

Chemiluminescent immunoassay technology: what does it change in autoantibody detection?

Luigi Cinquanta et al.

AUTOIMMUNITY HIGHLIGHTS (2017)

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Article Oncology

Merkel Cell Carcinomas Arising in Autoimmune Disease Affected Patients Treated with Biologic Drugs, Including Anti-TNF

John Charles Rotondo et al.

CLINICAL CANCER RESEARCH (2017)

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Review Genetics & Heredity

Advancements in Next-Generation Sequencing

Shawn E. Levy et al.

ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 17 (2016)

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Article Biochemistry & Molecular Biology

Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components

Keith Pardee et al.

CELL (2016)

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Article Dermatology

Hypermethylation-Induced Inactivation of the IRF6 Gene as a Possible Early Event in Progression of Vulvar Squamous Cell Carcinoma Associated With Lichen Sclerosus

John Charles Rotondo et al.

JAMA DERMATOLOGY (2016)

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Article Cell Biology

Gene Expression Changes in Progression of Cervical Neoplasia Revealed by Microarray Analysis of Cervical Neoplastic Keratinocytes

John Charles Rotondo et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2015)

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Article Immunology

Protocol for Metagenomic Virus Detection in Clinical Specimens

Claudia Kohl et al.

EMERGING INFECTIOUS DISEASES (2015)

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Article Multidisciplinary Sciences

Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

Stephen K. Gire et al.

SCIENCE (2014)

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Article Virology

Serological assays for emerging coronaviruses: Challenges and pitfalls

Benjamin Meyer et al.

VIRUS RESEARCH (2014)

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Article Biochemistry & Molecular Biology

Methylation loss at H19 imprinted gene correlates with methylenetetrahydrofolate reductase gene promoter hypermethylation in semen samples from infertile males

John C. Rotondo et al.

EPIGENETICS (2013)

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Review Immunology

Multi-faceted functions of secretory IgA at mucosal surfaces

Blaise Corthesy

FRONTIERS IN IMMUNOLOGY (2013)

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Article Biochemical Research Methods

Exploring single-sample SNP and INDEL calling with whole-genome de novo assembly

Heng Li

BIOINFORMATICS (2012)

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Article Obstetrics & Gynecology

Methylenetetrahydrofolate reductase gene promoter hypermethylation in semen samples of infertile couples correlates with recurrent spontaneous abortion

J. C. Rotondo et al.

HUMAN REPRODUCTION (2012)

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Article Pathology

Opportunities and Challenges Associated with Clinical Diagnostic Genome Sequencing A Report of the Association for Molecular Pathology

Iris Schrijver et al.

JOURNAL OF MOLECULAR DIAGNOSTICS (2012)

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Article Virology

Virus Pathogen Database and Analysis Resource (ViPR): A Comprehensive Bioinformatics Database and Analysis Resource for the Coronavirus Research Community

Brett E. Pickett et al.

VIRUSES-BASEL (2012)

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Article Chemistry, Analytical

High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number

Benjamin J. Hindson et al.

ANALYTICAL CHEMISTRY (2011)

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Review Immunology

IgM in microbial infections: Taken for granted?

Rachael Racine et al.

IMMUNOLOGY LETTERS (2009)

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Article Multidisciplinary Sciences

Environmental genome shotgun sequencing of the Sargasso Sea

JC Venter et al.

SCIENCE (2004)

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Article Immunology

SARS and common viral infections

JK Louie et al.

EMERGING INFECTIOUS DISEASES (2004)

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Review Biotechnology & Applied Microbiology

Angiotensin-I-converting enzyme and its relatives

JF Riordan

GENOME BIOLOGY (2003)

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