Related references
Note: Only part of the references are listed.Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP)
Rency Mathew et al.
SCIENTIFIC REPORTS (2021)
Heme Detoxification in the Malaria Parasite: A Target for Antimalarial Drug Development
Katherine A. de Villiers et al.
ACCOUNTS OF CHEMICAL RESEARCH (2021)
How Malaria Parasites Acquire Nutrients From Their Host
Natalie A. Counihan et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
IPC 2.0: prediction of isoelectric point and pKa dissociation constants
Lukasz Pawel Kozlowski
NUCLEIC ACIDS RESEARCH (2021)
A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites
Jakob Birnbaum et al.
SCIENCE (2020)
The natural function of the malaria parasite's chloroquine resistance transporter
Sarah H. Shafik et al.
NATURE COMMUNICATIONS (2020)
Phosphomimetic substitution at Ser-33 of the chloroquine resistance transporter PfCRT reconstitutes drug responses in Plasmodium falciparum
Cecilia P. Sanchez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay
Jerzy M. Dziekan et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Overexpression of the HECT ubiquitin ligase PfUT prolongs the intraerythrocytic cycle and reduces invasion efficiency of Plasmodium falciparum
Monika Jankowska-Doellken et al.
SCIENTIFIC REPORTS (2019)
Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis
Min Zhang et al.
SCIENCE (2018)
Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter
Andrew H. Lee et al.
SCIENTIFIC REPORTS (2018)
Differential time-dependent volumetric and surface area changes and delayed induction of new permeation pathways in P-falciparum-infected hemoglobinopathic erythrocytes
Mailin Waldecker et al.
CELLULAR MICROBIOLOGY (2017)
Iron is a substrate of the Plasmodium falciparum chloroquine resistance transporter PfCRT in Xenopus oocytes
Naziha Bakouh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Plasmodium falciparum chloroquine resistance transporter (PfCRT) isoforms PH1 and PH2 perturb vacuolar physiology
Paul S. Callaghan et al.
MALARIA JOURNAL (2016)
Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology
Stanislaw J. Gabryszewski et al.
PLOS PATHOGENS (2016)
Hemoglobin Degrading Proteases of Plasmodium falciparum as Antimalarial Drug Targets
Tabish Qidwai
CURRENT DRUG TARGETS (2015)
Balancing drug resistance and growth rates via compensatory mutations in the Plasmodium falciparum chloroquine resistance transporter
Ines Petersen et al.
MOLECULAR MICROBIOLOGY (2015)
Plasmodium falciparum chloroquine resistance transporter is a H+-coupled polyspecific nutrient and drug exporter
Narinobu Juge et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities
Serena Pulcini et al.
SCIENTIFIC REPORTS (2015)
Quinine Dimers Are Potent Inhibitors of the Plasmodium falciparum Chloroquine Resistance Transporter and Are Active against Quinoline-Resistant P. falciparum
Christine A. Hrycyna et al.
ACS CHEMICAL BIOLOGY (2014)
Malarial hemozoin: From target to tool
Lorena M. Coronado et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)
Multiple Drugs Compete for Transport via the Plasmodium falciparum Chloroquine Resistance Transporter at Distinct but Interdependent Sites
Sebastiano Bellanca et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system
Mehdi Ghorbal et al.
NATURE BIOTECHNOLOGY (2014)
Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism
Ian A. Lewis et al.
PLOS GENETICS (2014)
Glutathione Transport: A New Role for PfCRT in Chloroquine Resistance
Eva-Maria Patzewitz et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Iron and heme metabolism in Plasmodium falciparum and the mechanism of action of artemisinins
Nectarios Klonis et al.
CURRENT OPINION IN MICROBIOLOGY (2013)
Inducible Knockdown of Plasmodium Gene Expression Using the glmS Ribozyme
Parichat Prommana et al.
PLOS ONE (2013)
IDEOM: an Excel interface for analysis of LC-MS-based metabolomics data
Darren J. Creek et al.
BIOINFORMATICS (2012)
Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics
Robert L. Summers et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
PfCRT and its role in antimalarial drug resistance
Andrea Ecker et al.
TRENDS IN PARASITOLOGY (2012)
Untargeted Metabolomics Reveals a Lack Of Synergy between Nifurtimox and Eflornithine against Trypanosoma brucei
Isabel M. Vincent et al.
PLOS NEGLECTED TROPICAL DISEASES (2012)
PeakML/mzMatch: A File Format, Java Library, R Library, and Tool-Chain for Mass Spectrometry Data Analysis
Richard A. Scheltema et al.
ANALYTICAL CHEMISTRY (2011)
Genetic linkage analyses redefine the roles of PfCRT and PfMDR1 in drug accumulation and susceptibility in Plasmodium falciparum
Cecilia P. Sanchez et al.
MOLECULAR MICROBIOLOGY (2011)
Transporters as mediators of drug resistance in Plasmodium falciparum
Cecilia P. Sanchez et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY (2010)
Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine
Juliana Martha Sa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Dissecting the components of quinine accumulation in Plasmodium falciparum
Cecilia P. Sanchez et al.
MOLECULAR MICROBIOLOGY (2008)
Spinning disk confocal microscopy of live, intraerythrocytic malarial parasites. 2. Altered vacuolar volume regulation in drug resistant malaria
Bojana Gligorijevic et al.
BIOCHEMISTRY (2006)
XCMS: Processing mass spectrometry data for metabolite profiling using Nonlinear peak alignment, matching, and identification
CA Smith et al.
ANALYTICAL CHEMISTRY (2006)
The new permeability pathways induced by the malaria parasite in the membrane of the infected erythrocyte: Comparison of results using different experimental techniques
H Ginsburg et al.
JOURNAL OF MEMBRANE BIOLOGY (2004)
The malaria parasite's chloroquine resistance transporter is a member of the drug/metabolite transporter superfamily
RE Martin et al.
MOLECULAR BIOLOGY AND EVOLUTION (2004)
Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening
M Smilkstein et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Chloroquine resistance modulated in vitro by expression levels of the Plasmodium falciparum chloroquine resistance transporter
KL Waller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Multiple transporters associated with malaria parasite responses to chloroquine and quinine
JB Mu et al.
MOLECULAR MICROBIOLOGY (2003)
Excess hemoglobin digestion and the osmotic stability of Plasmodium falciparum-infected red blood cells
VL Lew et al.
BLOOD (2003)
Analysis of the antimalarial drug resistance protein Pfcrt expressed in yeast
HB Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations
ABS Sidhu et al.
SCIENCE (2002)
Intraerythrocytic Plasmodium falciparum utilizes only a fraction of the amino acids derived from the digestion of host cell cytosol for the biosynthesis of its proteins
M Krugliak et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2002)
Mutations in the P-falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance
DA Fidock et al.
MOLECULAR CELL (2000)
Share Paper
