The Race for Global Equitable Access to COVID-19 Vaccines

Review Infectious Diseases

Comparing COVID-19 vaccines for their characteristics, efficacy and effectiveness against SARS-CoV-2 and variants of concern: a narrative review

Thibault Fiolet et al.

Summary: Overall, COVID-19 vaccines have high efficacy against the original strain and variants of concern, with rare serious adverse events. However, prices vary significantly for different vaccines.

CLINICAL MICROBIOLOGY AND INFECTION (2022)

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Review Medicine, General & Internal

Systematic Review and Meta-Analysis of COVID-19 Vaccination Acceptance

Mohd Noor Norhayati et al.

Summary: Vaccination is crucial in controlling the COVID-19 pandemic. This study analyzed the global vaccine acceptance rate and found a pooled proportion of 61%. However, there is a need to enhance public awareness and increase vaccine uptake to achieve herd immunity.

FRONTIERS IN MEDICINE (2022)

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Article Public, Environmental & Occupational Health

COVAX and equitable access to COVID-19 vaccines

Katelyn J. Yoo et al.

Summary: The study evaluates the equity of COVID-19 vaccine allocation and distribution through COVAX. It finds that countries and territories with lower GDP per capita benefit more from vaccine distribution, especially when adjusting for population age group.

BULLETIN OF THE WORLD HEALTH ORGANIZATION (2022)

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Article Medicine, General & Internal

Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B.1.1.529) and delta (B.1.617.2) variants in England: a cohort study

Tommy Nyberg et al.

Summary: The Omicron variant shows lower severity compared to Delta, especially in terms of hospital admission and death, with significant variations by age. Unvaccinated cases experience a larger reduction in intrinsic severity, while vaccinated cases experience reduced vaccine effectiveness. Booster vaccination with mRNA vaccines provides over 70% protection against hospitalization and death in breakthrough Omicron infections.

LANCET (2022)

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Review Health Policy & Services

Management of COVID-19 vaccines cold chain logistics: a scoping review

Mathumalar Loganathan Fahrni et al.

Summary: This study aimed to synthesize evidence for efficient cold chain management of COVID vaccines. The findings suggest that regulatory requirements, packaging and storage, and transportation and distribution are key factors in the efficient cold chain management. Recommendations were made to improve formulation stability, end-product storage conditions, and monitoring technologies.

JOURNAL OF PHARMACEUTICAL POLICY AND PRACTICE (2022)

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Letter Surgery

Monkeypox: Prioritizing public health through early intervention and treatment

Mathumalar Loganathan Fahrni et al.

INTERNATIONAL JOURNAL OF SURGERY (2022)

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Letter Surgery

Monkeypox outbreak: New zoonotic alert after the COVID-19 pandemic

Amit Sharma et al.

INTERNATIONAL JOURNAL OF SURGERY (2022)

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Review Immunology

COVID-19 Vaccination Hesitancy among Healthcare Workers-A Review

Christopher J. Peterson et al.

Summary: The COVID-19 pandemic and its associated vaccine have brought attention to vaccine hesitancy among healthcare workers. Reasons for hesitancy include concerns about safety and efficacy, mistrust of government and institutions, waiting for more data, and feeling that personal rights are being infringed upon. Being a physician, having more advanced education, and previous vaccination habits are frequently associated with vaccine acceptance.

VACCINES (2022)

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Review Infectious Diseases

Mix-and-Match COVID-19 Vaccinations (Heterologous Boost): A Review

Ishan Garg et al.

Summary: Various safe and effective COVID-19 vaccines are available, and a prime-boost vaccination regimen is recommended. Heterologous prime-boost vaccination may provide comparable immune response and address concerns such as vaccine supply, adverse effects, emerging strains, inadequate response in immunocompromised individuals, and waning immunity.

INFECTIOUS DISEASE REPORTS (2022)

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Article Biochemistry & Molecular Biology

A global survey of potential acceptance of a COVID-19 vaccine

Jeffrey V. Lazarus et al.

Summary: Survey data from 19 countries reveals varying attitudes towards acceptance of a COVID-19 vaccine, with trust in government being linked to vaccine confidence.

NATURE MEDICINE (2021)

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Editorial Material Medicine, General & Internal

Covax must go beyond proportional allocation of covid vaccines to ensure fair and equitable access

Lisa M. Herzog et al.

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Review Medicine, General & Internal

Challenges in ensuring global access to COVID-19 vaccines: production, affordability, allocation, and deployment

Olivier J. Wouters et al.

Summary: The COVID-19 pandemic may not end globally until vaccines that protect against severe disease and drive herd immunity are widely distributed. While vaccines have been authorized for human use in many countries, achieving global control of COVID-19 requires not only licensed vaccines but also mass production, affordable pricing, global allocation, and wide local deployment.

LANCET (2021)

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Article Multidisciplinary Sciences

J&J’s single-dose COVID vaccine raises hopes for faster rollout

Heidi Ledford

NATURE (2021)

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Article Medicine, General & Internal

Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons

Tom T. Shimabukuro et al.

Summary: Preliminary data indicates that there are no obvious safety signals among pregnant women who received mRNA Covid-19 vaccines, but more data is needed for further confirmation. Adverse reactions such as injection-site pain were reported more frequently in pregnant women, but most pregnancies resulted in live births with some cases of preterm birth and small size for gestational age.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Editorial Material Immunology

Access to and equitable distribution of COVID-19 vaccine in low-income countries

Krishna Prasad Acharya et al.

NPJ VACCINES (2021)

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Article Biochemistry & Molecular Biology

COVID-19 vaccine acceptance and hesitancy in low- and middle-income countries

Julio S. Solis Arce et al.

Summary: The acceptance of COVID-19 vaccines in LMICs is higher compared to the United States and Russia, with a focus on personal protection and concerns about side effects. Healthcare workers are the most trusted sources of guidance in LMICs for COVID-19 vaccines, suggesting that prioritizing vaccine distribution to these countries could help advance global immunization coverage.

NATURE MEDICINE (2021)

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Article Health Care Sciences & Services

Effectiveness of heterologous ChAdOx1 nCoV-19 and mRNA prime-boost vaccination against symptomatic Covid-19 infection in Sweden: A nationwide cohort study

Peter Nordstrom et al.

Summary: The study suggests that heterologous prime-boost vaccination with ChAdOx1 nCoV-19 and mRNA vaccines is an effective alternative to increase population immunity against Covid-19, with higher effectiveness compared to homologous vaccination. These findings could have significant implications for vaccination strategies and logistics in the battle against the Covid-19 pandemic.

LANCET REGIONAL HEALTH-EUROPE (2021)

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Editorial Material Multidisciplinary Sciences