4.7 Review

Fabrication, Properties, and Biomedical Applications of Calcium-Containing Cellulose-Based Composites

Journal

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fbioe.2022.937266

Keywords

cellulose; composites; hydroxyapatite; calcium carbonate; biomedical application

Funding

  1. National Key R and D Program of China [2019YFC1905901]
  2. Key Production Innovative Development Plan of the Southern Bingtuan [2019DB007]

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Calcium-containing cellulose-based composites are highly promising in the biomedical field due to their high mechanical strength, excellent osteoconductivity, biocompatibility, biodegradation, and bioactivity. This mini-review article summarizes the synthesis of calcium-containing cellulose-based composites using various methods and highlights the development on their fabrication, properties, and applications. The existing problems and future developments of cellulose-based composites are also discussed.
Calcium-containing cellulose-based composites possess the advantages of high mechanical strength, excellent osteoconductivity, biocompatibility, biodegradation, and bioactivity, which represent a promising application system in the biomedical field. Calcium-containing cellulose-based composites have become the hotspot of study of various biomedical fields. In this mini-review article, the synthesis of calcium-containing cellulose-based composites is summarized via a variety of methods such as the biomimetic mineralization method, microwave method, co-precipitation method, hydrothermal method, freeze-drying method, mechanochemical reaction method, and ultrasound method. The development on the fabrication, properties, and applications of calcium-containing cellulose-based composites is highlighted. The as-existed problems and future developments of cellulose-based composites are provided. It is expected that calcium-containing cellulose-based composites are the ideal candidate for biomedical application.

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