4.6 Article

A High Spatiotemporal Iontronic Single-Cell Viscometer

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

A General Strategy to Control Viscosity Sensitivity of Molecular Rotor-Based Fluorophores

Songtao Ye et al.

Summary: By chemically installing extended pi-rich alternating carbon-carbon linkages between the rotational electron donors and acceptors of RBFs, the lack of control of their viscosity sensitivity has been resolved. The length of the linkage strongly influences the viscosity sensitivity, providing the possibility to design RBFs with different viscosity sensitivities. RBFs can differentiate misfolded protein oligomers and insoluble aggregates in test tubes and live cells through a dual-color imaging strategy.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

A Supersmall Single-Cell Nanosensor for Intracellular K+ Detection

Xiao-Mei Shi et al.

Summary: A supersmall biomimetic K+ nanosensor was developed for electrochemically detecting intracellular K+ in a minimally invasive manner, showing sensitive and reversible response to K+ fluctuations. This nanosensor is proven to be an accessible tool for tracking stimulus-induced K+ fluctuation under physiological conditions.

CCS CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

An Integrated Photoelectrochemical Nanotool for Intracellular Drug Delivery and Evaluation of Treatment Effect

Yi-Fan Ruan et al.

Summary: A dual-functional photocathodic single-cell nanotool has been developed for direct intracellular drug delivery and evaluation of oxidative stress, pushing the boundary of current single-cell electroanalysis.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

An Integrated Electrochemical Nanodevice for Intracellular RNA Collection and Detection in Single Living Cell

Hai-Yan Wang et al.

Summary: Novel tools for single-cell interrogation combined with electrochemical techniques have been utilized to collect and detect intracellular RNA, enabling systematic studies on oncogenic miR-10b expression levels in different breast cells. This research expands the ability to study gene expression and cellular heterogeneity at the single-cell level.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Multidisciplinary Sciences

Combined quantum tunnelling and dielectrophoretic trapping for molecular analysis at ultra-low analyte concentrations

Longhua Tang et al.

Summary: The practical implementation of quantum tunnelling for high-resolution study of nanoscale objects is hindered by the lack of simple, stable probes.

NATURE COMMUNICATIONS (2021)

Article Chemistry, Analytical

Twin Nanopipettes for Real-Time Electrochemical Monitoring of Cytoplasmic Microviscosity at a Single-Cell Level

Si-Yuan Yu et al.

Summary: This study presents a novel electrochemical single-cell measurement method using twin nanopipettes for real-time and long-term detection of cytoplasmic microviscosity. The correlation between chemotherapy and CPMV alterations allows for the assessment of external stimuli evolution. The use of twin nanopipettes for electrochemical CPMV monitoring of single living cells is expected to inspire further interest in advanced single-cell analysis.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Intracellular Wireless Analysis of Single Cells by Bipolar Electrochemiluminescence Confined in a Nanopipette

Yuling Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Multidisciplinary

Correlating Molecule Count and Release Kinetics with Vesicular Size Using Open Carbon Nanopipettes

Keke Hu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Biochemistry & Molecular Biology

Cellular Control of Viscosity Counters Changes in Temperature and Energy Availability

Laura B. Persson et al.

Article Multidisciplinary Sciences

A dual-labeling probe to track functional mitochondria-lysosome interactions in live cells

Qixin Chen et al.

NATURE COMMUNICATIONS (2020)

Article Chemistry, Multidisciplinary

The double life of conductive nanopipette: a nanopore and an electrochemical nanosensor

Rui Jia et al.

CHEMICAL SCIENCE (2020)

Review Chemistry, Multidisciplinary

Confined Nanopipette Sensing: From Single Molecules, Single Nanoparticles, to Single Cells

Ru-Jia Yu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Electrochemical Measurements of Reactive Oxygen and Nitrogen Species inside Single Phagolysosomes of Living Macrophages

Keke Hu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Chemistry, Multidisciplinary

Electrochemical Monitoring of ROS/RNS Homeostasis Within Individual Phagolysosomes Inside Single Macrophages

Xin-Wei Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Ferroptosis Accompanied by •OH Generation and Cytoplasmic Viscosity Increase Revealed via Dual-Functional Fluorescence Probe

Hongyu Li et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Chemistry, Physical

Electrolyte-based ionic control of functional oxides

Chris Leighton

NATURE MATERIALS (2019)

Article Nanoscience & Nanotechnology

Nanoscale tweezers for single-cell biopsies

Binoy Paulose Nadappuram et al.

NATURE NANOTECHNOLOGY (2019)

Article Chemistry, Multidisciplinary

A Multifunctional Chemical Probe for the Measurement of Local Micropolarity and Microviscosity in Mitochondria

Arturo Jimenez-Sanchez et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Multidisciplinary Sciences

Direct electrochemical observation of glucosidase activity in isolated single lysosomes from a living cell

Rongrong Pan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Chemistry, Multidisciplinary

Ultrasmall Nanopipette: Toward Continuous Monitoring of Redox Metabolism at Subcellular Level

Juan Song et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Multidisciplinary Sciences

Manipulating and visualizing the dynamic aggregation-induced emission within a confined quartz nanopore

Yi-Lun Ying et al.

NATURE COMMUNICATIONS (2018)

Article Physics, Multidisciplinary

Surface Fluctuations and Coalescence of Nucleolar Droplets in the Human Cell Nucleus

Christina M. Caragine et al.

PHYSICAL REVIEW LETTERS (2018)

Article Multidisciplinary Sciences

Viscous control of cellular respiration by membrane lipid composition

Itay Budin et al.

SCIENCE (2018)

Article Cell Biology

Interaction Dynamics Determine Signaling and Output Pathway Responses

Klement Stojanovski et al.

CELL REPORTS (2017)

Article Neurosciences

Clinical and neuropathological features of ALS/FTD with TIA1 mutations

Veronica Hirsch-Reinshagen et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)

Article Chemistry, Multidisciplinary

Real-Time Intracellular Measurements of ROS and RNS in Living Cells with Single Core-Shell Nanowire Electrodes

Xin-Wei Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Multidisciplinary Sciences

Mapping intracellular mechanics on micropatterned substrates

Kalpana Mandal et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Chemistry, Multidisciplinary

Activatable Rotor for Quantifying Lysosomal Viscosity in Living Cells

Lu Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Article Chemistry, Multidisciplinary

A Self-Calibrating Bipartite Viscosity Sensor for Mitochondria

Zhigang Yang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Review Biochemistry & Molecular Biology

Stress granules: The Tao of RNA triage

Paul Anderson et al.

TRENDS IN BIOCHEMICAL SCIENCES (2008)

Article Physics, Multidisciplinary

Fractional Stokes-Einstein and Debye-Stokes-Einstein relations in a network-forming liquid

Stephen R. Becker et al.

PHYSICAL REVIEW LETTERS (2006)