☆ 4.0 Article

Investigation of developmental toxicity of favipiravir on fetal bone and embryonic development

BIRTH DEFECTS RESEARCH (2022)

Related references

Note: Only part of the references are listed.

Article Obstetrics & Gynecology

Favipiravir exposure and pregnancy outcome of COVID-19 patients

Zeynep Tirmikcioglu

Summary: This study reports the outcomes of 29 pregnancies involving the use of favipiravir. The results suggest that favipiravir is unlikely to be a major human teratogen during pregnancy. However, larger studies are needed due to limited research experience for a more comprehensive risk assessment.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2022)

Add to Collection

Review Infectious Diseases

Role of favipiravir in the treatment of COVID-19

Shashank Joshi et al.

Summary: Favipiravir has shown promising results in clinical studies worldwide, demonstrating potential efficacy against COVID-19, and is being included in treatment protocols by multiple countries.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

Add to Collection

Article Infectious Diseases

Evaluation of the effectiveness and safety of adding ivermectin to treatment in severe COVID-19 patients

Nurullah Okumus et al.

Summary: This study aimed to investigate the presence of gene mutations affecting ivermectin metabolism in patients with severe COVID-19 pneumonia, and evaluate the effectiveness and safety of ivermectin treatment. Clinical improvement rate was higher in the ivermectin group compared to the control group after 5 days of treatment. Ivermectin showed potential in increasing clinical recovery and improving prognostic laboratory parameters in severe COVID-19 patients, suggesting it could be considered as an alternative treatment option.

BMC INFECTIOUS DISEASES (2021)

Add to Collection

Article Toxicology

The protective role of curcumin against toxic effect of nonylphenol on bone development

P. Alisan Suna et al.

Summary: The study aimed to investigate the protective effects of curcumin against the toxic effects of nonylphenol on bone development. Results showed that offspring exposed to nonylphenol had lower weights and bone measurements, while curcumin-treated groups showed similarities to the control group. The findings suggest a potential benefit of curcumin in accelerating bone formation and mitigating the negative impact of nonylphenol exposure on bone development.

HUMAN & EXPERIMENTAL TOXICOLOGY (2021)

Add to Collection

Article Immunology

Favipiravir in the treatment of patients with SARS-CoV-2 RNA recurrent positive after discharge: A multicenter, open-label, randomized trial

Hong Zhao et al.

Summary: The study showed that favipiravir was effective and safe in treating patients with recurrent positive SARS-CoV-2 RNA. Patients treated with favipiravir had a significantly shorter duration of viral shedding and decreased inflammatory markers. Further large-scale, randomized, double-blind, placebo-controlled trials are needed to confirm these findings.

INTERNATIONAL IMMUNOPHARMACOLOGY (2021)

Add to Collection

Article Pediatrics

Favipiravir use in children with COVID-19 and acute kidney injury: is it safe?

Yasemin Ozsurekci et al.

Summary: This study aimed to share the experience of using favipiravir in pediatric patients with COVID-19 and kidney impairment. Results showed that favipiravir may be a suitable therapeutic option for COVID-19 patients with kidney injury without needing dose adjustment.

PEDIATRIC NEPHROLOGY (2021)

Add to Collection

Review Medicine, Research & Experimental

Emerging treatment strategies for COVID-19 infection

Maria Gavriatopoulou et al.

Summary: COVID-19 is a novel emerging infectious disease caused by SARS-CoV-2 originating from Wuhan, China and has led to a worldwide pandemic. The typical manifestations include fever, sore throat, and dyspnea, with supportive care being the current standard of treatment as effective antiviral options are still lacking.

CLINICAL AND EXPERIMENTAL MEDICINE (2021)

Add to Collection

Article Microbiology

A Prospective, Randomized, Open-Label Trial of Early versus Late Favipiravir Therapy in Hospitalized Patients with COVID-19

Yohei Doi et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2020)

Add to Collection

Article Multidisciplinary Sciences

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity

Suzanne J. F. Kaptein et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Add to Collection

Article Virology

Antiviral mechanisms of candidate chemical medicines and traditional Chinese medicines for SARS-CoV-2 infection

Chang Li et al.

VIRUS RESEARCH (2020)

Add to Collection

Review Obstetrics & Gynecology

Placental transfer and safety in pregnancy of medications under investigation to treat coronavirus disease 2019

Margaux Louchet et al.

AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM (2020)

Add to Collection

Article Public, Environmental & Occupational Health

Impact of prenatal exposure to bisphenol A on pregnant rats: Fetal bone development and immunohistochemistry implications

Emre Atay et al.

TOXICOLOGY AND INDUSTRIAL HEALTH (2019)

Add to Collection

Review Infectious Diseases

Influenza virus polymerase inhibitors in clinical development

Frederick G. Hayden et al.

CURRENT OPINION IN INFECTIOUS DISEASES (2019)

Add to Collection

Review Pharmacology & Pharmacy

Favipiravir as a potential countermeasure against neglected and emerging RNA viruses

Leen Delang et al.

ANTIVIRAL RESEARCH (2018)

Add to Collection

Review Multidisciplinary Sciences

Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase

Yousuke Furuta et al.

PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2017)

Add to Collection

Article Endocrinology & Metabolism

Bone Alkaline Phosphatase and Tartrate-Resistant Acid Phosphatase: Potential Co-regulators of Bone Mineralization

Cecilia Halling Linder et al.

CALCIFIED TISSUE INTERNATIONAL (2017)

Add to Collection

Article Medicine, General & Internal

Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

Daouda Sissoko et al.

PLOS MEDICINE (2016)

Add to Collection

Article Infectious Diseases

Broad Spectrum Antiviral Activity of Favipiravir (T-705): Protection from Highly Lethal Inhalational Rift Valley Fever

Amy L. Caroline et al.

PLOS NEGLECTED TROPICAL DISEASES (2014)

Add to Collection

Article Oncology

Assessment of a Nonsteroidal Aromatase Inhibitor, Letrozole, in Juvenile Rats

Louise Pouliot et al.

BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY (2013)

Add to Collection

Meeting Abstract Oncology

The clinical significance of SWI/SNF complex in pancreatic cancer

Masakatsu Numata et al.

JOURNAL OF CLINICAL ONCOLOGY (2013)

Add to Collection

Article Developmental Biology

Atlas of rat fetal skeleton double stained for bone and cartilage

E Menegola et al.

TERATOLOGY (2001)

Add to Collection

© Peeref 2019-2024. All rights reserved.