The Economic Burden of Chromosome Translocations and the Benefits of Enhanced Screening for Cattle Breeding

Article Cell Biology

Rapid Multi-Hybridisation FISH Screening for Balanced Porcine Reciprocal Translocations Suggests a Much Higher Abnormality Rate Than Previously Appreciated

Rebecca E. O'Connor et al.

Summary: Pigs are the world's leading source of meat protein, but hypoprolific boars may incur significant economic and environmental losses. Reciprocal translocations are a leading cause of porcine hypoprolificacy, which may be significantly under-reported using traditional karyotyping. A multiple hybridisation fluorescence in situ hybridisation strategy can detect translocations, highlighting the importance of pre-emptive screening before boars enter breeding programs.

CELLS (2021)

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Review Genetics & Heredity

Chromosomal Aberrations in Cattle

Beata Holeckova et al.

Summary: This study reviews the mechanisms and consequences of the most important bovine chromosomal aberrations, Robertsonian translocations and reciprocal translocations, as well as the application of bovine cell cultures in genotoxicity studies in cattle.

GENES (2021)

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Article Agriculture, Dairy & Animal Science