☆ 4.4 Article

Outcomes of Cytomegalovirus Viremia Treatment in Critically Ill Patients with COVID-19 Infection

OPEN FORUM INFECTIOUS DISEASES (2022)

Related references

Note: Only part of the references are listed.

Review Medicine, Research & Experimental

COVID-19-associated opportunistic infections: a snapshot on the current reports

Amir Abdoli et al.

Summary: Treatment of severe COVID-19 cases with immunosuppressive therapy has shown promising results in controlling cytokine storm syndrome, but it also increases the risk of opportunistic infections. Several opportunistic infections have been reported in COVID-19 patients, posing challenges for diagnosis and treatment.

CLINICAL AND EXPERIMENTAL MEDICINE (2022)

Add to Collection

Article Infectious Diseases

Secondary infections in patients hospitalized with COVID-19: incidence and predictive factors

Marco Ripa et al.

Summary: The study aimed to describe the incidence and predictive factors of secondary infections in COVID-19 patients. Risk factors identified for secondary infections included low lymphocyte count, baseline PaO2/FiO2 decrease, and ICU admission within the first 48 hours.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

Add to Collection

Article Respiratory System

Fatal cytomegalovirus pneumonia in a critically ill patient with COVID-19

Saori Amiya et al.

Summary: COVID-19 can lead to severe lymphopenia and respiratory failure, increasing the risk of secondary infections. This case highlights the potential risks of long-term steroid use and the necessity of routine monitoring for CMV infection in critically ill patients with COVID-19.

RESPIROLOGY CASE REPORTS (2021)

Add to Collection

Article Infectious Diseases

EBV DNA increase in COVID-19 patients with impaired lymphocyte subpopulation count

Stefania Paolucci et al.

Summary: This study monitored the immunologic profile and opportunistic viral DNA increase in Italian patients with COVID-19 to identify markers of disease severity. It found a correlation between reduced CD8(+) T cells and NK counts, elevated EBV DNA levels, and COVID-19 severity, highlighting the importance of further evaluating the relationship between EBV load and disease severity in longitudinal studies.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

Add to Collection

Review Infectious Diseases

Antimicrobial stewardship in the ICU in COVID-19 times: the known unknowns

Jeroen Schouten et al.

Summary: Issues surrounding antimicrobial stewardship in the context of COVID-19 patients include the challenge of distinguishing between infectious and non-infectious causes of respiratory deterioration, the relevance of biomarkers like procalcitonin, the consideration of cytomegalovirus reactivation, and the complexities in diagnosing COVID-19-associated invasive aspergillosis. Additionally, there is a need to take into account altered pharmacokinetic/pharmacodynamic properties when prescribing antimicrobial therapy in this population, emphasizing the importance of further research to address unknowns in this area.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2021)

Add to Collection

Letter Infectious Diseases

Cytomegalovirus infection in critically ill patients with COVID-19

Takayuki Niitsu et al.

JOURNAL OF INFECTION (2021)

Add to Collection

Article Critical Care Medicine

Preemptive ganciclovir for mechanically ventilated patients with cytomegalovirus reactivation

Laurent Papazian et al.

Summary: In patients mechanically ventilated for more than 96 hours with CMV reactivation in blood, preemptive ganciclovir did not improve the outcome.

ANNALS OF INTENSIVE CARE (2021)

Add to Collection

Article Medicine, General & Internal

SARS-CoV-2 and Cytomegalovirus Co-Infections-A Case Series of Critically Ill Patients

Patricia Moniz et al.

Summary: The COVID-19 pandemic has led to increased cases of CMV reactivation in critically ill patients, although the exact relationship between the two remains unclear. The significant immune suppression in severe COVID-19 patients may impact CMV reactivation, potentially affecting the clinical course. Multiple confounding factors in these patients will pose challenges for future research.

JOURNAL OF CLINICAL MEDICINE (2021)

Add to Collection

Letter Immunology

Ganciclovir Therapy for CMV Viremia in a Patient on VV ECMO With COVID-19 After Treatment With Tocilizumab

Leah Amundson et al.

INFECTIOUS DISEASES IN CLINICAL PRACTICE (2021)

Add to Collection

Article Infectious Diseases

High incidence of Epstein-Barr virus, cytomegalovirus, and human-herpes virus-6 reactivations in critically ill patients with COVID-19

A. Simonnet et al.

Summary: Critically ill patients with COVID-19 in the ICU are prone to herpesvirus reactivation, particularly with EBV, which occurs early and is associated with longer ICU stays.

INFECTIOUS DISEASES NOW (2021)

Add to Collection

Article Medicine, General & Internal

Cytomegalovirus haemorrhagic colitis complicating COVID-19 in an immunocompetent critically ill patient: A case report

Sophie Leemans et al.

Summary: In severe COVID-19 cases, suspicion for opportunistic coinfections should be lowered; persistent digestive disturbances may prompt discussions on serum CMV polymerase chain reaction and colonoscopy.

CLINICAL CASE REPORTS (2021)

Add to Collection

Article Medicine, General & Internal

Tocilizumab-induced cytomegalovirus colitis in a patient with COVID-19

Mohamad Y. Khatib et al.

Summary: Clinicians should monitor for early signs of CMV reactivation in COVID-19 patients presenting with gastrointestinal complications after receiving immunosuppressive therapy, to prevent life-threatening complications and mortality.

CLINICAL CASE REPORTS (2021)

Add to Collection

Article Gastroenterology & Hepatology

Cytomegalovirus haemorrhagic enterocolitis associated with severe infection with COVID-19

Warren C. Carll et al.

Summary: This case report describes a patient with SARS-CoV-2 who developed haemorrhagic enterocolitis after recovering from respiratory failure with venovenous extracorporeal membrane oxygenation. The study suggests a possible link between systemic coinfection/reactivation of cytomegalovirus and the prolonged resolution of gastrointestinal inflammation in COVID-19 patients. Additionally, the proposed synergistic pathophysiologic mechanisms for enterocolitis complicating severe COVID-19 infection include T lymphocyte depletion, immune response dysregulation, use of immunomodulators, and high concentration of ACE-2 receptors in the gastrointestinal tract for COVID-19 virus.

BMJ OPEN GASTROENTEROLOGY (2021)

Add to Collection

Article Geriatrics & Gerontology

The ancient and the new: is there an interaction between cytomegalovirus and SARS-CoV-2 infection?

Paul Moss

IMMUNITY & AGEING (2020)

Add to Collection

Article Medicine, General & Internal

Cytomegalovirus: A Troll in the ICU? Overview of the Literature and Perspectives for the Future

Jolien Schildermans et al.

FRONTIERS IN MEDICINE (2020)

Add to Collection

Review Virology

Why the elderly appear to be more severely affected byCOVID-19: The potential role of immunosenescence andCMV

Seilesh Kadambari et al.

REVIEWS IN MEDICAL VIROLOGY (2020)

Add to Collection

Article Hematology

Cytomegalovirus-Induced Gastrointestinal Bleeding and Pancreatitis Complicating Severe Covid-19 Pneumonia: A Paradigmatic Case

Giacomo Marchi et al.

MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES (2020)

Add to Collection

Letter Critical Care Medicine

SARS-CoV-2 infection as a risk factor for herpesviridae reactivation: consider the potential influence of corticosteroid therapy

Patrick M. Honore et al.

CRITICAL CARE (2020)

Add to Collection

Article Public, Environmental & Occupational Health

A misleading CMV myocarditis during the COVID-19 pandemic: case report

Sara Oualim et al.

PAN AFRICAN MEDICAL JOURNAL (2020)

Add to Collection

Letter Critical Care Medicine

Herpes simplex virus and cytomegalovirus reactivations among severe COVID-19 patients

Pierre Le Balc'h et al.

CRITICAL CARE (2020)

Add to Collection

Article Immunology

Definitions of Cytomegalovirus Infection and Disease in Transplant Patients for Use in Clinical Trials

Per Ljungman et al.

CLINICAL INFECTIOUS DISEASES (2017)

Add to Collection

Article Medicine, General & Internal

Effect of Ganciclovir on IL-6 Levels Among Cytomegalovirus-Seropositive Adults With Critical Illness A Randomized Clinical Trial

Ajit P. Limaye et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

Add to Collection

Article Cell Biology

Cytomegalovirus infection is associated with increased mortality in the older population

George M. Savva et al.

AGING CELL (2013)

Add to Collection

Article Critical Care Medicine

Prevalence and mortality associated with cytomegalovirus infection in nonimmunosuppressed patients in the intensive care unit

Andre C. Kalil et al.

CRITICAL CARE MEDICINE (2009)

Add to Collection

Article Critical Care Medicine

Cytomegalovirus infection in critically ill patients: a systematic review

Ryosuke Osawa et al.

CRITICAL CARE (2009)

Add to Collection

© Peeref 2019-2024. All rights reserved.