Journal
NEOBIOTA
Volume 74, Issue -, Pages 93-103Publisher
PENSOFT PUBLISHERS
DOI: 10.3897/neobiota.74.82394
Keywords
Cat; fox; gene drive; invasive mammals; mice; rabbit; rat; spatial model
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Funding
- Australian Research Council [LP180100748]
- NSW Government
- SA Government Research, Commercialisation and Startup Fund
- Phoenix HPC service at the University of Adelaide
- Australian Research Council [LP180100748] Funding Source: Australian Research Council
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CRISPR-based gene drives offer solutions for controlling invasive species, but their feasibility varies among different sized species.
CRISPR-based gene drives offer novel solutions for controlling invasive alien species, which could ulti-mately extend eradication efforts to continental scales. Gene drives for suppressing invasive alien verte-brates are now under development. Using a landscape-scale individual-based model, we present the first estimates of times to eradication for long-lived alien mammals. We show that demography and life-history traits interact to determine the scalability of gene drives for vertebrate pest eradication. Notably, optimism around eradicating smaller-bodied pests (rodents and rabbits) with gene-drive technologies does not easily translate into eradication of larger-bodied alien species (cats and foxes).
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