Related references
Note: Only part of the references are listed.Targeting p300/CBP Attenuates Hepatocellular Carcinoma Progression through Epigenetic Regulation of Metabolism
Ling-Yan Cai et al.
CANCER RESEARCH (2021)
Acquired deficiency of peroxisomal dicarboxylic acid catabolism is a metabolic vulnerability in hepatoblastoma
Huabo Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
HBXIP drives metabolic reprogramming in hepatocellular carcinoma cells via METTL3-mediated m6A modification of HIF-1α
Nanmu Yang et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2021)
C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism
Yu Zhang et al.
ONCOGENE (2021)
Advances in systemic therapy for the first-line treatment of unresectable HCC
Arndt Vogel et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2021)
Adaptive and Constitutive Activations of Malic Enzymes Confer Liver Cancer Multilayered Protection Against Reactive Oxygen Species
Derek Lee et al.
HEPATOLOGY (2021)
The mTOR-Autophagy Axis and the Control of Metabolism
Nerea Deleyto-Seldas et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Multifunctional Fructose 1,6-Bisphosphate Aldolase as a Therapeutic Target
David B. Pirovich et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2021)
Disruption of SIRT7 Increases the Efficacy of Checkpoint Inhibitor via MEF2D Regulation of Programmed Cell Death 1 Ligand 1 in Hepatocellular Carcinoma Cells
Junyu Xiang et al.
GASTROENTEROLOGY (2020)
MFN1-dependent alteration of mitochondrial dynamics drives hepatocellular carcinoma metastasis by glucose metabolic reprogramming
Ze Zhang et al.
BRITISH JOURNAL OF CANCER (2020)
Targeting aerobic glycolysis by dichloroacetate improves Newcastle disease virus-mediated viro-immunotherapy in hepatocellular carcinoma
Gang Meng et al.
BRITISH JOURNAL OF CANCER (2020)
Diagnosis and management of toxicities of immune checkpoint inhibitors in hepatocellular carcinoma
Bruno Sangro et al.
JOURNAL OF HEPATOLOGY (2020)
Autophagy and autophagy-related proteins in cancer
Xiaohua Li et al.
MOLECULAR CANCER (2020)
Direct inhibition of the TLR4/MyD88 pathway by geniposide suppresses HIF-1α-independent VEGF expression and angiogenesis in hepatocellular carcinoma
Cheng Zhang et al.
BRITISH JOURNAL OF PHARMACOLOGY (2020)
Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment
Pei-pei Hou et al.
MOLECULAR CELL (2020)
BNIP3L-Dependent Mitophagy Promotes HBx-Induced Cancer Stemness of Hepatocellular Carcinoma Cells via Glycolysis Metabolism Reprogramming
Yuan-Yuan Chen et al.
CANCERS (2020)
PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression
Yotaro Kudo et al.
CANCER CELL (2020)
Inhibition of pyruvate dehydrogenase kinase-1 by dicoumarol enhances the sensitivity of hepatocellular carcinoma cells to oxaliplatin via metabolic reprogramming
Huadan Xu et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2020)
Glutamic-Pyruvic Transaminase 1 Facilitates Alternative Fuels for Hepatocellular Carcinoma Growth-A Small Molecule Inhibitor, Berberine
Wei Guo et al.
CANCERS (2020)
PKM2 inhibition may reverse therapeutic resistance to transarterial chemoembolization in hepatocellular carcinoma
Sean P. Martin et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)
Mechanisms of replication and repair in mitochondrial DNA deletion formation
Gabriele A. Fontana et al.
NUCLEIC ACIDS RESEARCH (2020)
Polyphenolic Proanthocyanidin-B2 suppresses proliferation of liver cancer cells and hepatocellular carcinogenesis through directly binding and inhibiting AKT activity
Guijun Liu et al.
REDOX BIOLOGY (2020)
Tumor-Associated Macrophages in Tumor Immunity
Yueyun Pan et al.
FRONTIERS IN IMMUNOLOGY (2020)
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance
Xing Huang et al.
AUTOPHAGY (2019)
Sirtuin-1/Mitochondrial Ribosomal Protein S5 Axis Enhances the Metabolic Flexibility of Liver Cancer Stem Cells
Zhihao Wei et al.
HEPATOLOGY (2019)
Thymidine phosphorylase promotes malignant progression in hepatocellular carcinoma through pentose Warburg effect
Qiang Zhang et al.
CELL DEATH & DISEASE (2019)
Inhibition of glycogen catabolism induces intrinsic apoptosis and augments multikinase inhibitors in hepatocellular carcinoma cells
Shrikant Barot et al.
EXPERIMENTAL CELL RESEARCH (2019)
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner
Zhaoyu Qin et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Glycolytic activation of peritumoral monocytes fosters immune privilege via the PFKFB3-PD-L1 axis in human hepatocellular carcinoma
Dong-Ping Chen et al.
JOURNAL OF HEPATOLOGY (2019)
Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion
Deepali Sawant et al.
NATURE IMMUNOLOGY (2019)
Hepatocellular Carcinoma
Augusto Villanueva
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation
Man-Hsin Hung et al.
CELL DEATH & DISEASE (2019)
Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma
Qiang Gao et al.
CELL (2019)
Effects of a DPP4 Inhibitor on Progression of NASH-related HCC and the p62/Keap1/Nrf2-Pentose Phosphate Pathway in a Mouse Model
Takumi Kawaguchi et al.
LIVER CANCER (2019)
Mitochondrial fragmentation limits NK cell-based tumor immunosurveillance
Xiaohu Zheng et al.
NATURE IMMUNOLOGY (2019)
Mitochondrial metabolic study guided by proteomics analysis in hepatocellular carcinoma cells surviving long-term incubation with the highest dose of sorafenib
Jing Bai et al.
AGING-US (2019)
The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy
Fernando Souza-Fonseca-Guimaraes et al.
TRENDS IN IMMUNOLOGY (2019)
NK Cell Metabolism and TGFβ - Implications for Immunotherapy
Karen Slattery et al.
FRONTIERS IN IMMUNOLOGY (2019)
LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway
Yin-Li Zheng et al.
THERANOSTICS (2019)
AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells
Zhenhong Ni et al.
AUTOPHAGY (2018)
TLR-mediated metabolic reprogramming in the tumor microenvironment: potential novel strategies for cancer immunotherapy
Lan Huang et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2018)
High mobility group protein B1 controls liver cancer initiation through yes-associated protein -dependent aerobic glycolysis
Ruochan Chen et al.
HEPATOLOGY (2018)
EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation
Jong-Ho Lee et al.
MOLECULAR CELL (2018)
Role of PKM2 in directing the metabolic fate of glucose in cancer: a potential therapeutic target
Gustav van Niekerk et al.
CELLULAR ONCOLOGY (2018)
Mitochondrial-dynamics-in-cancer-induced-cachexia
Miranda van der Ende et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2018)
O-GIcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma
Weicheng Wu et al.
CELL DEATH & DISEASE (2018)
Aberrant Metabolism in Hepatocellular Carcinoma Provides Diagnostic and Therapeutic Opportunities
Serena De Matteis et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation
Le Li et al.
NATURE COMMUNICATIONS (2018)
Adenosinergic Signaling Alters Natural Killer Cell Functional Responses
Andrea M. Chambers et al.
FRONTIERS IN IMMUNOLOGY (2018)
mTORC1 as the main gateway to autophagy
Yoana Rabanal-Ruiz et al.
SIGNALLING MECHANISMS IN AUTOPHAGY (2017)
Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B
Paola Fisicaro et al.
NATURE MEDICINE (2017)
Metabolic Interactions in the Tumor Microenvironment
Costas A. Lyssiotis et al.
TRENDS IN CELL BIOLOGY (2017)
Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions
Orianne Olivares et al.
NATURE COMMUNICATIONS (2017)
Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis
Ewelina Krzywinska et al.
NATURE COMMUNICATIONS (2017)
Multi-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells
Qi Xie et al.
SCIENTIFIC REPORTS (2017)
The Macronutrients, Appetite, and Energy Intake
Alicia L. Carreiro et al.
ANNUAL REVIEW OF NUTRITION, VOL 36 (2016)
The Warburg effect and drug resistance
Bhaskar Bhattacharya et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming
Michael D. Buck et al.
CELL (2016)
The Emerging Hallmarks of Cancer Metabolism
Natalya N. Pavlova et al.
CELL METABOLISM (2016)
LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
Almut Brand et al.
Cell Metabolism (2016)
The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction
Nicole E. Scharping et al.
IMMUNITY (2016)
Metabolic Reprogramming Supports IFN-γ Production by CD56bright NK Cells
Sinead E. Keating et al.
JOURNAL OF IMMUNOLOGY (2016)
The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V. Liberti et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
Tetsuya Saito et al.
NATURE COMMUNICATIONS (2016)
Distinct Metabolic Requirements of Exhausted and Functional Virus-Specific CD8 T Cells in the Same Host
Anna Schurich et al.
Cell Reports (2016)
Macrophage PPARγ inhibits Gpr132 to mediate the anti-tumor effects of rosiglitazone
Wing Yin Cheng et al.
ELIFE (2016)
Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression
Isaac S. Harris et al.
CANCER CELL (2015)
Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
Suzanne L. Topalian et al.
CANCER CELL (2015)
Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma
Ling-Fei Zhang et al.
EMBO JOURNAL (2015)
Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells
Pamela M. Odorizzi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Hepatitis B virus stimulates G6PD expression through HBx-mediated Nrf2 activation
B. Liu et al.
CELL DEATH & DISEASE (2015)
C-terminal-truncated hepatitis B virus X protein enhances the development of diethylnitrosamine-induced hepatocellular carcinogenesis
Ivan Quetier et al.
JOURNAL OF GENERAL VIROLOGY (2015)
Upregulation of CD147 protects hepatocellular carcinoma cell from apoptosis through glycolytic switch via HIF-1 and MCT-4 under hypoxia
Xia Ke et al.
HEPATOLOGY INTERNATIONAL (2014)
mTORC1-Dependent Metabolic Reprogramming Is a Prerequisite for NK Cell Effector Function
Raymond P. Donnelly et al.
JOURNAL OF IMMUNOLOGY (2014)
Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides
Kivanc Birsoy et al.
NATURE (2014)
mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity
Shih-Chin Cheng et al.
SCIENCE (2014)
The pentose phosphate pathway and cancer
Krushna C. Patra et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
A dual role for autophagy in a murine model of lung cancer
Shuan Rao et al.
NATURE COMMUNICATIONS (2014)
Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer
Krushna C. Patra et al.
CANCER CELL (2013)
Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells
Zaheed Husain et al.
JOURNAL OF IMMUNOLOGY (2013)
Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
Yoshinobu Ichimura et al.
MOLECULAR CELL (2013)
Modulation of oxidative stress as an anticancer strategy
Chiara Gorrini et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Molecular Mechanisms of HBV-Associated Hepatocarcinogenesis
Francesca Guerrieri et al.
SEMINARS IN LIVER DISEASE (2013)
Mitochondrial DNA alterations and mitochondrial dysfunction in the progression of hepatocellular carcinoma
Chia-Chi Hsu et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2013)
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
Patrick S. Ward et al.
CANCER CELL (2012)
Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors
Yan Xia et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development
Gerritje J. W. van der Windt et al.
IMMUNITY (2012)
K-Ras and B-Raf oncogenes inhibit colon epithelial polarity establishment through up-regulation of c-myc
Kirti Magudia et al.
JOURNAL OF CELL BIOLOGY (2012)
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
Dimitrios Anastasiou et al.
NATURE CHEMICAL BIOLOGY (2012)
Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release
Kristina Goetze et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2011)
Phagocytosis, a Potential Mechanism for Myeloid-Derived Suppressor Cell Regulation of CD8+ T Cell Function Mediated through Programmed Cell Death-1 and Programmed Cell Death-1 Ligand Interaction
Young-June Kim et al.
JOURNAL OF IMMUNOLOGY (2011)
Otto Warburg's contributions to current concepts of cancer metabolism
Willem H. Koppenol et al.
NATURE REVIEWS CANCER (2011)
The causes of cancer revisited: Mitochondrial malignancy and ROS-induced oncogenic transformation - Why mitochondria are targets for cancer therapy
Stephen J. Ralph et al.
MOLECULAR ASPECTS OF MEDICINE (2010)
HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
Charles J. David et al.
NATURE (2010)
Autophagy Suppresses Tumorigenesis through Elimination of p62
Robin Mathew et al.
CELL (2009)
Cancer cell metabolism: Warburg and beyond
Peggy P. Hsu et al.
CELL (2008)
Correlation between copy number of mitochondrial DNA and clinico-pathologic parameters of hepatocellular carcinoma
S Yamada et al.
EJSO (2006)
Mitochondrial O2-• and H2O2 mediate glucose deprivation-induced cytotoxicity and oxidative stress in human cancer cells
IM Ahmad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Ras is involved in the negative control of autophagy through the class IPI3-kinase
S Furuta et al.
ONCOGENE (2004)
CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression
P Kirk et al.
EMBO JOURNAL (2000)