4.7 Article

Carpal Tunnel Syndrome and Ulnar Nerve Entrapment Are Associated with Impaired Psychological Health in Adults as Appraised by Their Increased Use of Psychotropic Medication

Journal

JOURNAL OF CLINICAL MEDICINE
Volume 11, Issue 13, Pages -

Publisher

MDPI
DOI: 10.3390/jcm11133871

Keywords

nerve compression; carpal tunnel syndrome; carpal tunnel surgery; ulnar nerve entrapment; cubital tunnel syndrome; psychotropic drugs; psychological health; socioeconomical factors; national quality register

Funding

  1. Swedish Research Council [2017-01321, 2022-01942]
  2. Swedish Diabetes Foundation [DIA2020492]
  3. Region Skane and Lund University [2018-Projekt0104]
  4. Skane University Hospital [2019-659]
  5. Almroth Foundation
  6. Kockska foundation
  7. Magnus Bergvall Foundation [2020-03612]
  8. Stig and Ragna Gorthon Foundation
  9. Elly Olsson's Foundation for scientific research
  10. Formas [2022-01942] Funding Source: Formas

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This study aimed to investigate the psychological health of individuals diagnosed and surgically treated for carpal tunnel syndrome (CTS), ulnar nerve entrapment (UNE), or both, by examining the use of psychotropic drugs. The study found that individuals with nerve compression disorders had a higher risk of using psychotropic drugs, and this risk was associated with factors such as age, gender, income, and occupational qualification level.
We aimed to study psychological health, as approximated by the use of psychotropic drugs, in a population diagnosed and surgically treated for carpal tunnel syndrome (CTS) or ulnar nerve entrapment (UNE), or both, also considering the demographic and socioeconomic factors of the individuals. Linking data from five large national registers, use of psychotropics (at least one dispensation during the first year after the surgery or the baseline date) was examined in around 5.8 million people 25-80 years old residing in Sweden 2010. Among these individuals, 9728 (0.17%), 890 (0.02%) and 149 (0.00%) were identified as diagnosed and surgically treated for CTS, UNE, or both, respectively. As much as 28%, 34% and 36% in each group, respectively, used psychotropic drugs, compared with 19% in the general population. Regression analyses showed a general higher risk for use of psychotropics related to these nerve compression disorders, to higher age, being a woman, and having low income or low occupational qualification level. Individuals born outside of Sweden had a lower risk. We conclude that surgically treated individuals with a nerve compression disorder have an increased risk of impaired psychological health. Caregivers should be aware of the risk and provide necessary attention.

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