Towards Accurate and Precise Image-Guided Radiotherapy: Clinical Applications of the MR-Linac

Advances in image-guided radiotherapy have brought about improved oncologic outcomes and reduced toxicity. The next generation of image guidance in the form of magnetic resonance imaging (MRI) will improve visualization of tumors and make radiation treatment adaptation possible. In this review, we discuss the role that MRI plays in radiotherapy, with a focus on the integration of MRI with the linear accelerator. The MR linear accelerator (MR-Linac) will provide real-time imaging, help assess motion management, and provide online adaptive therapy. Potential advantages and the current state of these MR-Linacs are highlighted, with a discussion of six different clinical scenarios, leading into a discussion on the future role of these machines in clinical workflows.

Automated summary

Advances in image-guided radiotherapy, particularly the application of magnetic resonance imaging (MRI), have improved oncologic outcomes and reduced toxicity. The integration of MRI with a linear accelerator in the MR-Linac provides real-time imaging, motion management assessment, and online adaptive therapy, offering potential advantages in different clinical scenarios and enhancing the future role of these machines in clinical workflows.