4.7 Article

Gut Microbiome Modification through Dietary Intervention in Patients with Colorectal Cancer: Protocol for a Prospective, Interventional, Controlled, Randomized Clinical Trial in Patients with Scheduled Surgical Intervention for CRC

Related references

Note: Only part of the references are listed.
Article Microbiology

Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes

Leah Guthrie et al.

Summary: Gut microbiota metabolism generates a wide range of microbiome-dependent metabolites (MDMs), which vary greatly between individuals. Uremic MDMs (uMDMs), including phenylacetylglutamine (PAG), p-cresol sulfate (PCS), and indoxyl sulfate (IS), accumulate during renal failure and are associated with poor outcomes. Targeted dietary interventions may reduce toxic MDM generation, but it is unclear if inter-individual differences in diet or gut microbiome dominantly contribute to MDM variance.

CELL HOST & MICROBE (2022)

Article Gastroenterology & Hepatology

Low-Fat, High-Fiber Diet Reduces Markers of Inflammation and Dysbiosis and Improves Quality of Life in Patients With Ulcerative Colitis

Julia Fritsch et al.

Summary: In patients with UC, both a low-fat, high-fiber diet and an improved standard American diet increased quality of life, but the low-fat, high-fiber diet decreased markers of inflammation and reduced intestinal dysbiosis in fecal samples.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

Review Microbiology

Gut microbiota in human metabolic health and disease

Yong Fan et al.

Summary: The intestinal microbiota plays a significant role in human metabolic health, potentially contributing to the development of common metabolic disorders when dysregulated. Current research is shifting towards cause-and-effect studies and utilizing high-throughput human multi-omics data to identify potential molecular mechanisms behind these associations.

NATURE REVIEWS MICROBIOLOGY (2021)

Review Medicine, General & Internal

Role of Diet in Colorectal Cancer Incidence Umbrella Review of Meta-analyses of Prospective Observational Studies

Sajesh K. Veettil et al.

Summary: This study provides a comprehensive evaluation of the association between dietary factors and the incidence of colorectal cancer, identifying numerous significant associations between specific dietary components and CRC risk.

JAMA NETWORK OPEN (2021)

Article Biochemistry & Molecular Biology

Relationships of Gut Microbiota Composition, Short-Chain Fatty Acids and Polyamines with the Pathological Response to Neoadjuvant Radiochemotherapy in Colorectal Cancer Patients

Lidia Sanchez-Alcoholado et al.

Summary: This study suggests that gut microbiota composition plays a role in the response to cancer therapies in CRC patients. Responders had higher microbial diversity and abundance of butyrate-producing bacteria, as well as higher levels of specific metabolites, while non-responders exhibited a microbiota rich in pro-inflammatory species.Ultimately, a baseline consortium of five bacterial species was identified as potential predictors of CRC treatment outcome.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Nutrition & Dietetics

Effect of Dietary Inulin Supplementation on the Gut Microbiota Composition and Derived Metabolites of Individuals Undergoing Hemodialysis: A Pilot Study

Annabel Biruete et al.

Summary: This study aimed to evaluate the impact of a 4-week supplementation of prebiotic fiber inulin on the gut microbiota composition and microbial metabolites in patients undergoing hemodialysis (HD). The results showed that both inulin and maltodextrin did not lead to significant shifts in the fecal microbiota and gut microbiota-derived metabolites, potentially due to high variability among participants and an unexpected increase in short-chain fatty acid excretion with maltodextrin.

JOURNAL OF RENAL NUTRITION (2021)

Review Chemistry, Medicinal

Effects of Fish n-3 PUFAs on Intestinal Microbiota and Immune System

Cinzia Parolini

MARINE DRUGS (2019)

Review Biochemistry & Molecular Biology

Oral Bacteria and Intestinal Dysbiosis in Colorectal Cancer

Ioannis Koliarakis et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Gastroenterology & Hepatology

Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies

NaNa Keum et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)

Review Immunology

The gut microbiome: Relationships with disease and opportunities for therapy

Juliana Durack et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2019)

Article Public, Environmental & Occupational Health

Paper-Based Versus Web-Based Versions of Self-Administered Questionnaires, Including Food-Frequency Questionnaires: Prospective Cohort Study

Itziar Zazpe et al.

JMIR PUBLIC HEALTH AND SURVEILLANCE (2019)

Review Medicine, Research & Experimental

Role of gut microbiota in intestinal wound healing and barrier function

Ashfaqul Alam et al.

TISSUE BARRIERS (2018)

Review Biochemistry & Molecular Biology

Impact of Omega-3 Fatty Acids on the Gut Microbiota

Lara Costantini et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Multidisciplinary Sciences

Gut microbiome development along the colorectal adenoma-carcinoma sequence

Qiang Feng et al.

NATURE COMMUNICATIONS (2015)

Review Gastroenterology & Hepatology

The gut microbiota and the metabolic health of the host

Susan A. Joyce et al.

CURRENT OPINION IN GASTROENTEROLOGY (2014)

Article Gastroenterology & Hepatology

Significant Changes in the Intestinal Environment After Surgery in Patients with Colorectal Cancer

Seiji Ohigashi et al.

JOURNAL OF GASTROINTESTINAL SURGERY (2013)

Article Biochemistry & Molecular Biology

Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

Mauro Castellarin et al.

GENOME RESEARCH (2012)

Article Nutrition & Dietetics

Prebiotic treatment reduced preneoplastic lesions through the downregulation of toll like receptor 4 in a chemo-induced carcinogenic model

Masanobu Fukuda et al.

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2011)

Review Biochemistry & Molecular Biology

Bacterial contributions to mammalian gut development

LV Hooper

TRENDS IN MICROBIOLOGY (2004)