Journal
JOURNAL FOR IMMUNOTHERAPY OF CANCER
Volume 10, Issue 7, Pages -Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/jitc-2022-004936
Keywords
immunotherapy; cell engineering; biomarkers; tumor; adjuvants; pharmaceutic
Categories
Funding
- NHLBI [R01HL143020]
- Creative Materials Discovery Program through the National Research Foundation of Korea [2019M3D1A1078938]
- ZTI Biosciences [2020A015360]
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Cancer immunotherapy is a powerful anticancer therapy, but the interaction between tumors and the immune system is complex and not well understood. Optical fluorescence imaging is a technique that allows for visualizing immune cells and monitoring immune response during immunotherapy.
Cancer immunotherapy has emerged as one of the most powerful anticancer therapies. However, the details on the interaction between tumors and the immune system are complicated and still poorly understood. Optical fluorescence imaging is a technique that allows for the visualization of fluorescence-labeled immune cells and monitoring of the immune response during immunotherapy. To this end, near-infrared (NIR) light has been adapted for optical fluorescence imaging because it is relatively safe and simple without hazardous ionizing radiation and has relatively deeper tissue penetration into living organisms than visible fluorescence light. In this review, we discuss state-of-the-art NIR optical imaging techniques in cancer immunotherapy to observe the dynamics, efficacy, and responses of the immune components in living organisms. The use of bioimaging labeling techniques will give us an understanding of how the immune system is primed and ultimately developed.
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