Related references
Note: Only part of the references are listed.Molecular Mechanisms Underlying Neurotransmitter Release
Josep Rizo
ANNUAL REVIEW OF BIOPHYSICS (2022)
Control of neurotransmitter release by two distinct membrane-binding faces of the Munc13-1 C1C2B region
Marcial Camacho et al.
ELIFE (2021)
Phosphatidylinositol and phosphatidylinositol-3-phosphate activate HOPS to catalyze SNARE assembly, allowing small headgroup lipids to support the terminal steps of membrane fusion
Thomas Torng et al.
MOLECULAR BIOLOGY OF THE CELL (2021)
Re-examining how Munc13-1 facilitates opening of syntaxin-1
Magdalena Magdziarek et al.
PROTEIN SCIENCE (2020)
Asymmetric Rab activation of vacuolar HOPS to catalyze SNARE complex assembly
Thomas Torng et al.
MOLECULAR BIOLOGY OF THE CELL (2020)
Munc13 activates the Munc18-1/syntaxin-1 complex and enables Munc18-1 to primeSNAREassembly
Xianping Wang et al.
EMBO JOURNAL (2020)
The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation
Travis J. Eisemann et al.
ELIFE (2020)
The Interaction of Munc18-1 Helix 11 and 12 with the Central Region of the VAMP2 SNARE Motif Is Essential for SNARE Templating and Synaptic Transmission
Timon Andre et al.
ENEURO (2020)
Open syntaxin overcomes exocytosis defects of diverse mutants in C. elegans
Chi-Wei Tien et al.
NATURE COMMUNICATIONS (2020)
Membrane bridging by Munc13-1 is crucial for neurotransmitter release
Bradley Quade et al.
ELIFE (2019)
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
Dorothee Liebschner et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2019)
Munc18-1 is crucial to overcome the inhibition of synaptic vesicle fusion by αSNAP
Karolina P. Stepien et al.
NATURE COMMUNICATIONS (2019)
Multiple factors maintain assembled trans-SNARE complexes in the presence of NSF and αSNAP
Eric A. Prinslow et al.
ELIFE (2019)
Quantitative mass imaging of single biological macromolecules
Gavin Young et al.
SCIENCE (2018)
New tools for automated high-resolution cryo-EM structure determination in RELION-3
Jasenko Zivanov et al.
ELIFE (2018)
Munc18-1 catalyzes neuronal SNARE assembly by templating SNARE association
Junyi Jiao et al.
ELIFE (2018)
Tyrosine phosphorylation of Munc18-1 inhibits synaptic transmission by preventing SNARE assembly
Marieke Meijer et al.
EMBO JOURNAL (2018)
UNC-18 and Tomosyn Antagonistically Control Synaptic Vesicle Priming Downstream of UNC-13 in Caenorhabditis elegans
Seungmee Park et al.
JOURNAL OF NEUROSCIENCE (2017)
A short region upstream of the yeast vacuolar Qa-SNARE heptad-repeats promotes membrane fusion through enhanced SNARE complex assembly
Hongki Song et al.
MOLECULAR BIOLOGY OF THE CELL (2017)
Simultaneous lipid and content mixing assays for in vitro reconstitution studies of synaptic vesicle fusion
Xiaoxia Liu et al.
NATURE PROTOCOLS (2017)
Autoinhibition of Munc18-1 modulates synaptobrevin binding and helps to enable Munc13-dependent regulation of membrane fusion
Ewa Sitarska et al.
ELIFE (2017)
Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN
Junjie Xu et al.
ELIFE (2017)
Conformational change of syntaxin linker region induced by Munc13s initiates SNARE complex formation in synaptic exocytosis
Shen Wang et al.
EMBO JOURNAL (2017)
Extension of Helix 12 in Munc18-1 Induces Vesicle Priming
Anders S. Munch et al.
JOURNAL OF NEUROSCIENCE (2016)
Functional synergy between the Munc13 C-terminal C1 and C2 domains
Xiaoxia Liu et al.
ELIFE (2016)
Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming
Xiaoyu Yang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
MEMBRANE FUSION A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly
Richard W. Baker et al.
SCIENCE (2015)
Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming
Xiaoyu Yang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Munc18-1-regulated stage-wise SNARE assembly underlying synaptic exocytosis
Lu Ma et al.
ELIFE (2015)
An Extended Helical Conformation in Domain 3a of Munc18-1 Provides a Template for SNARE ( Soluble N- Ethylmaleimidesensitive Factor Attachment Protein Receptor) Complex Assembly*
Daniel Parisotto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
A Pivotal Role for Pro-335 in Balancing the Dual Functions of Munc18-1 Domain-3a in Regulated Exocytosis
Gayoung Anna Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle
Thomas C. Suedhof
NEURON (2013)
Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation
Karen N. Colbert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Reconstitution of the Vital Functions of Munc18 and Munc13 in Neurotransmitter Release
Cong Ma et al.
SCIENCE (2013)
Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex
Cong Ma et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
SNARE Proteins Underpin Insulin-Regulated GLUT4 Traffic
Nia J. Bryant et al.
TRAFFIC (2011)
MolProbity: all-atom structure validation for macromolecular crystallography
Vincent B. Chen et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Binding of Munc18-1 to Synaptobrevin and to the SNARE Four-Helix Bundle
Yi Xu et al.
BIOCHEMISTRY (2010)
Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells
Marjorie Cote et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptid
Pawel Burkhardt et al.
EMBO JOURNAL (2008)
SNARE-mediated lipid mixing depends on the physical state of the vesicles
XC Chen et al.
BIOPHYSICAL JOURNAL (2006)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming
F Varoqueaux et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
A post-docking role for active zone protein Rim
SP Koushika et al.
NATURE NEUROSCIENCE (2001)
An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming
JE Richmond et al.
NATURE (2001)
Vam3p structure reveals conserved and divergent properties of syntaxins
I Dulubova et al.
NATURE STRUCTURAL BIOLOGY (2001)
Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex
KMS Misura et al.
NATURE (2000)
Synaptic assembly of the brain in the absence of neurotransmitter secretion
M Verhage et al.
SCIENCE (2000)