Association Between Prostate-Specific Antigen Screening and Prostate Cancer Mortality Among Non-Hispanic Black and Non-Hispanic White US Veterans

Article Oncology

Evaluating Prostate-Specific Antigen Screening for Young African American Men With Cancer

Edmund M. Qiao et al.

Summary: PSA screening is associated with reduced risk of high PSA levels, high Gleason score, metastatic disease, and prostate cancer-specific mortality in young African American men. However, the retrospective design of this study limits the precise estimation of screening effects, and prospective studies are needed to validate these findings.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2022)

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Review Oncology

Prostate Cancer Racial Disparities: A Systematic Review by the Prostate Cancer Foundation Panel

Brandon A. Mahal et al.

Summary: This study critically synthesizes the available evidence on prostate cancer disparities and emphasizes the importance of racially diverse studies to understand and address these disparities. The findings highlight the need for intervention studies and clinical trials that include Black and other men with prostate cancer to reduce the widening disparities.

EUROPEAN UROLOGY ONCOLOGY (2022)

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Article Oncology

The Impact of Intensifying Prostate Cancer Screening in Black Men: A Model-Based Analysis

Yaw A. Nyame et al.

Summary: The study found that intensified PSA screening in Black men is expected to reduce mortality more than that estimated under historical screening. Limiting screening to men younger than 70 years is expected to help reduce overdiagnosis.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2021)

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Article Oncology

Racial and Ethnic Variation in PSA Testing and Prostate Cancer Incidence Following the 2012 USPSTF Recommendation

Kevin H. Kensler et al.

Summary: The frequency of prostate cancer screening varies by race and ethnicity, with a steeper decline in PSA testing among younger non-Hispanic Black men relative to non-Hispanic White men since 2012. The incidence rate ratio for localized prostate cancer modestly increased for non-Hispanic Black men compared to non-Hispanic White men after 2012.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2021)

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Article Oncology