4.5 Review

Sexually transmitted infections and female reproductive health

Journal

NATURE MICROBIOLOGY
Volume 7, Issue 8, Pages 1116-1126

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41564-022-01177-x

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Funding

  1. Doris Duke Charitable Foundation COVID-19 Fund to Retain Clinician Scientists [2021255]
  2. UAB COVID-19 CARES Retention Program (CARES at UAB)

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Women are disproportionately affected by sexually transmitted infections (STIs) and this review examines the impact of non-HIV STIs on women's health. The review discusses recent advances and current challenges in the treatment and prevention of STIs.
Women are disproportionately affected by sexually transmitted infections (STIs) throughout life. In addition to their high prevalence in women, STIs have debilitating effects on female reproductive health due to female urogenital anatomy, socio-cultural and economic factors. In this Review, we discuss the prevalence and impact of non-HIV bacterial, viral and parasitic STIs on the reproductive and sexual health of cisgender women worldwide. We analyse factors affecting STI prevalence among transgender women and women in low-income settings, and describe the specific challenges and barriers to improved sexual health faced by these population groups. We also synthesize the latest advances in diagnosis, treatment and prevention of STIs. Women are more affected by sexually transmitted infections than men. This Review examines the impact of non-HIV STIs on women's health, and discusses recent advances and current challenges in the treatment and prevention of STIs.

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