4.7 Article

Identification and characterization of two Isatis indigotica O-methyltransferases methylating C-glycosylflavonoids

Related references

Note: Only part of the references are listed.
Article Biotechnology & Applied Microbiology

Two types of O-methyltransferase are involved in biosynthesis of anticancer methoxylated 4′-deoxyflavones in Scutellaria baicalensis Georgi

Meng-Ying Cui et al.

Summary: The study found that methoxylated flavones have strong ability to induce apoptosis and enhance bioactivity, with methoxylation not causing side effects on healthy cells. Both type I and type II OMT enzymes are involved in the biosynthesis of methoxylated flavones in S. baicalensis.

PLANT BIOTECHNOLOGY JOURNAL (2022)

Article Multidisciplinary Sciences

Controlled hydroxylations of diterpenoids allow for plant chemical defense without autotoxicity

Jiancai Li et al.

Summary: Many plant specialized metabolites play a role in herbivore defense, but interrupting their biosynthetic pathways can lead to autotoxicity. Research has shown that tobacco plants avoid autotoxicity by regulating metabolic modifications, while achieving herbivore defense through inhibition of herbivore sphingolipid biosynthesis.

SCIENCE (2021)

Article Biochemistry & Molecular Biology

Specific decorations of 17-hydroxygeranyilinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata

Sven Heiling et al.

Summary: This study confirmed the defensive function of glucosylation and malonylation steps in HGL-DTG biosynthesis through gene silencing, highlighting that glucosylation is a critical step in generating defensive metabolites.

PLANT CELL (2021)

Review Biochemistry & Molecular Biology

Leloir glycosyltransferases of natural product C-glycosylation: structure, mechanism and specificity

Gregor Tegl et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2020)

Article Multidisciplinary Sciences

Overexpression of the Sorghum bicolor SbCCoAOMT alters cell wall associated hydroxycinnamoyl groups

Hannah M. Tetreault et al.

PLOS ONE (2018)

Article Biochemistry & Molecular Biology

Phenylpropanoid profiling reveals a class of hydroxycinnamoyl glucaric acid conjugates in Isatis tinctoria leaves

Thi-Kieu-Oanh Nguyen et al.

PHYTOCHEMISTRY (2017)

Review Nutrition & Dietetics

Flavones: Food Sources, Bioavailability, Metabolism, and Bioactivity

Gregory L. Hostetler et al.

ADVANCES IN NUTRITION (2017)

Review Biotechnology & Applied Microbiology

Methylation of flavonoids: Chemical structures, bioactivities, progress and perspectives for biotechnological production

Niranjan Koirala et al.

ENZYME AND MICROBIAL TECHNOLOGY (2016)

Article Biochemistry & Molecular Biology

Enzymatic production of oroxylin A and hispidulin using a liverwort flavone 6-O-methyltransferase

Yu-Ying Zhang et al.

FEBS LETTERS (2016)

Article Plant Sciences

The Structure and Catalytic Mechanism of Sorghum bicolor Caffeoyl-CoA O-Methyltransferase

Alexander M. Walker et al.

PLANT PHYSIOLOGY (2016)

Review Oncology

Exploring the molecular targets of dietary flavonoid fisetin in cancer

Deeba N. Syed et al.

SEMINARS IN CANCER BIOLOGY (2016)

Article Peripheral Vascular Disease

Vasorelaxing and Antihypertensive Effects of 7,8-Dihydroxyflavone

Ruituo Huai et al.

AMERICAN JOURNAL OF HYPERTENSION (2014)

Article Plant Sciences

An O-methyltransferase modifies accumulation of methylated anthocyanins in seedlings of tomato

Maria Victoria Gomez Roldan et al.

PLANT JOURNAL (2014)

Article Biochemistry & Molecular Biology

A single amino acid determines position specificity of an Arabidopsis thaliana CCoAOMT-like O-methyltransferase

Christopher Ralf Wils et al.

FEBS LETTERS (2013)

Article Medicine, Research & Experimental

Studies on the anti-tumor activities of the soy isoflavone daidzein on murine neuroblastoma cells

F. H. Lo et al.

BIOMEDICINE & PHARMACOTHERAPY (2007)

Article Biochemical Research Methods

Characterization of C-glycosyl flavones O-glycosylated by liquid chromatography-tandem mass spectrometry

F. Ferreres et al.

JOURNAL OF CHROMATOGRAPHY A (2007)

Article Plant Sciences

Crystal structures of alfalfa caffeoyl coenzyme A 3-O-methyltransferase

JL Ferrer et al.

PLANT PHYSIOLOGY (2005)

Article Chemistry, Medicinal

Isolation, structure elucidation, and biological activity of flavone 6-C-glycosides from Allaria petiolata

Y Kumarasamy et al.

CHEMISTRY OF NATURAL COMPOUNDS (2004)

Article Biochemistry & Molecular Biology

A novel Mg2+-dependent O-methyltransferase in the phenylpropanoid metabolism of Mesembryanthemum crystallinum

M Ibdah et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

A flavonol O-methyltransferase from Catharanthus roseus performing two sequential methylations

S Cacace et al.

PHYTOCHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Functional expression of an Arabidopsis cDNA clone encoding a flavonol 3′-O-methyltransferase and characterization of the gene product

I Muzac et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)