Campylobacter Gastroenteritis Among Under-Five Children in Southwest Ethiopia

Background: Under-five children are at an increased risk for foodborne illnesses because of the ingenuousness of their immune system. Although Campylobacter species are one of the bacterial etiologies of gastroenteritis, Campylobacter gastroenteritis among under-five children is not well considered in Ethiopia. Therefore, this study aimed at exploring the prevalence, associated risk factors, and antibiotic susceptibility patterns of Campylobacter species among under-five children with diarrhea. Methods: The institution-based cross-sectional study was conducted among under-five children with diarrhea at Jimma Medical Center, southwestern Ethiopia from January 5 to April 21, 2020. Stool samples were collected and inoculated into Campylobacter agar medium. Isolation and identification were done using standard bacteriological techniques. Antibiotic susceptibility testing was conducted on Mueller-Hinton agar supplemented with 10% sheep blood using disk diffusion techniques. Bivariate and multivariate logistic regressions were used to assess the associated risk factors. Results: A total of 214 under-five children were enrolled. The prevalence of Campylobacter infection was 8.9%. Absence of caretakers' handwashing before preparation of food [AOR = 3.7, 95% CI: (1.2-10.8)], direct contact with domestic animals [AOR = 3.6, 95% CI: (1.0-12.7)], and consumption of raw dairy products [AOR = 4.5, 95% CI: (1.4-13.9)] are the factors associated with Campylobacter infection. Some Campylobacter species were found to be resistant to most available antibiotics. Conclusion: The magnitude of Campylobacter gastroenteritis indicates the need for routine isolation and identification of Campylobacter species from all under-five children clinically diagnosed with diarrhea. Species that are resistant to the drug of choice for Campylobacteriosis are also emerging. Health education on the importance of pasteurization of milk and caretakers' handwashing can mitigate the transmission. Mechanism of handling of domestic animals should be considered to reduce transmission of zoonotic diseases like Campylobacteriosis.

Automated summary

This study found a prevalence rate of 8.9% for Campylobacter infection among under-five children in Ethiopia. Factors associated with Campylobacter infection included absence of caretakers' handwashing, direct contact with domestic animals, and consumption of raw dairy products. Some Campylobacter strains showed resistance to antibiotics.