A global dataset for prevalence of Salmonella Gallinarum between 1945 and 2021

Pullorum disease and fowl typhoid are among the most significant poultry diseases worldwide. However, the global burden of these diseases remains unknown. Most importantly, the parameters contributing to the prevalence of Salmonella Gallinarum variants are not well documented. Therefore, in this study, we present a systematic review and meta-analysis of the global prevalence of Salmonella Gallinarum during 1945-2021. In total, 201 studies were identified for qualitative analysis (>900 million samples). The meta-analysis was subjected to over 183 screened studies. The global prevalence of S. Gallinarum (percentage of positive samples in total samples) was 8.54% (95% CI: 8.43-8.65) and showed a V-shaped recovery over time. Pullorum disease is most common in Asia, particularly in eastern China. Further investigations on chicken origin samples revealed significant differences in S. Gallinarum prevalence by gender, breed, raising mode, economic use, and growth stage, indicating a critical role of vertical transmission. Together, this study offered an updated, evidence-based dataset and knowledge regarding S. Gallinarum epidemics, which might significantly impact decision-making policy with targeted interventions.

Automated summary

This study presents a systematic review and meta-analysis of the global prevalence of Salmonella Gallinarum, which causes pullorum disease and fowl typhoid. The study found that pullorum disease is most common in Asia, especially in eastern China, and identified significant differences in the prevalence of S. Gallinarum based on factors such as gender, breed, raising mode, economic use, and growth stage of the chickens. Vertical transmission plays a critical role in the spread of this disease.