☆ 4.6 Article

Synergistic antitumor response with recombinant modified virus Ankara armed with CD40L and CD137L against peritoneal carcinomatosis

ONCOIMMUNOLOGY (2022)

Related references

Note: Only part of the references are listed.

Review Oncology

Immunomodulation by targeted anticancer agents

Giulia Petroni et al.

Summary: Targeted anticancer agents are designed to inhibit specific molecular alterations that support oncogenesis or tumor progression, but they may also have immunomodulatory effects that can influence therapeutic efficacy. Harnessing these effects could potentially lead to superior clinical outcomes.

CANCER CELL (2021)

Add to Collection

Article Oncology

Modulation of intratumoural myeloid cells, the hallmark of the anti-tumour efficacy induced by a triple combination: tumour-associated peptide, TLR-3 ligand and α-PD-1

Sara Zalba et al.

Summary: In a study on a non-inflamed tumor model, a combination therapy of HPV E7 long peptide and PIC administered intra-tumorally along with systemic anti-PD-1 mAb showed maximal anti-tumor efficacy. This combination induces an early inflammatory process that remodels the myeloid cell compartment, leading to an increase in effector CD8(+) T lymphocytes.

BRITISH JOURNAL OF CANCER (2021)

Add to Collection

Article Oncology

Intratumoral virotherapy with 4-1BBL armed modified vaccinia Ankara eradicates solid tumors and promotes protective immune memory

Maria Hinterberger et al.

Summary: Intratumoral virotherapy with MVA-TAA-4-1BBL led to control of established tumors, triggering proinflammatory changes and immunogenic cell death in the tumor microenvironment. This approach induced reactivation and expansion of potent tumor-specific CD8(+) T cells, resulting in tumor elimination and protective immunological memory against tumor rechallenge.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021)

Add to Collection

Review Oncology

Immunological configuration of ovarian carcinoma: features and impact on disease outcome

Jitka Fucikova et al.

Summary: This study comparatively summarizes the humoral and cellular features of primary and metastatic EOC, analyzes their impact on disease outcome, and proposes measures to alter them in support of treatment sensitivity and superior patient survival.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021)

Add to Collection

Article Oncology

An Efficient Prognostic Immune Scoring System For Colorectal Cancer Patients With Peritoneal Metastasis

Yamei Zhao et al.

Summary: The study found that Immunoscore and TBM score can predict the survival period of patients with colorectal cancer peritoneal metastases, with higher scores associated with longer overall survival. Additionally, peritoneal metastasis decreases the infiltration levels of T and B cells.

ONCOIMMUNOLOGY (2021)

Add to Collection

Article Oncology

Prognostic image-based quantification of CD8CD103 T cell subsets in high-grade serous ovarian cancer patients

S. T. Paijens et al.

Summary: CD103-positive tissue resident memory-like CD8(+) T cells have been associated with improved prognosis in various malignancies, including high-grade serous ovarian cancer (HGSOC). Quantification of CD8CD103 TRM was found to be superior to single CD8 or CD103 quantification in predicting survival, with a survival benefit observed only in HGSOC patients treated with primary cytoreductive surgery and no macroscopic tumor lesions post-surgery. This approach provides insights into prognostic stratification of HGSOC patients and may contribute to personalized treatment strategies in the future.

ONCOIMMUNOLOGY (2021)

Add to Collection

Article Oncology

Cellular cytotoxicity is a form of immunogenic cell death

Luna Minute et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)

Add to Collection

Article Biochemistry & Molecular Biology

A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer

Patrick A. Ott et al.

CELL (2020)

Add to Collection

Article Medicine, General & Internal

Phase 3 Efficacy Trial of Modified Vaccinia Ankara as a Vaccine against Smallpox

Phillip R. Pittman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Add to Collection

Article Multidisciplinary Sciences

Synergistic cancer immunotherapy combines MVA-CD40L induced innate and adaptive immunity with tumor targeting antibodies

Jose Medina-Echeverz et al.

NATURE COMMUNICATIONS (2019)

Add to Collection

Review Oncology

Vaccinia virus-mediated cancer immunotherapy: cancer vaccines and oncolytics

Zong Sheng Guo et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)

Add to Collection

Article Oncology

Sipuleucel-T for the treatment of prostate cancer: novel insights and future directions

Catherine E. Handy et al.

FUTURE ONCOLOGY (2018)

Add to Collection

Article Immunology

CD40L Expression Allows CD8+ T Cells to Promote Their Own Expansion and Differentiation through Dendritic Cells

Neil Q. Tay et al.

FRONTIERS IN IMMUNOLOGY (2017)

Add to Collection

Article Oncology

Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus

Emma Eriksson et al.

CLINICAL CANCER RESEARCH (2017)

Add to Collection

Review Oncology

Complications after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for treatment of peritoneal carcinomatosis: Risk factors for ICU admission and morbidity prognostic score

Sylvain Malfroy et al.

SURGICAL ONCOLOGY-OXFORD (2016)

Add to Collection

Article Multidisciplinary Sciences

Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb

Bettina Weigelin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Add to Collection

Article Biochemical Research Methods

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

Yang Liao et al.

BIOINFORMATICS (2014)

Add to Collection

Article Biochemical Research Methods

Trimmomatic: a flexible trimmer for Illumina sequence data

Anthony M. Bolger et al.

BIOINFORMATICS (2014)

Add to Collection

Article Biochemical Research Methods

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin et al.

BIOINFORMATICS (2013)

Add to Collection

Review Gastroenterology & Hepatology

Peritoneal carcinomatosis

Federico Coccolini et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2013)

Add to Collection

Article Biochemical Research Methods

Molecular signatures database (MSigDB) 3.0

Arthur Liberzon et al.

BIOINFORMATICS (2011)

Add to Collection

Article Oncology

Adjuvant Combination and Antigen Targeting as a Strategy to Induce Polyfunctional and High-Avidity T-Cell Responses against Poorly Immunogenic Tumors

Fernando Aranda et al.

CANCER RESEARCH (2011)

Add to Collection

Article Biochemical Research Methods

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

Mark D. Robinson et al.

BIOINFORMATICS (2010)

Add to Collection

© Peeref 2019-2024. All rights reserved.