Journal
FRONTIERS IN IMMUNOLOGY
Volume 13, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2022.939768
Keywords
circRNA; host-virus interactions; viral infection; DNA viruses; RNA viruses
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Funding
- National Natural Science Foundation of China [31872424, 32072792, 31972620]
- Priority Academic Program of Development of Jiangsu Higher Education Institutions
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This review summarizes the biogenesis, functions, and future prospects of circular RNAs (circRNAs) derived from viruses and hosts. The study is important for understanding viral-encoded circRNAs during viral infections.
Circular RNAs (circRNAs) as novel regulatory molecules have been recognized in diverse species, including viruses. The virus-derived circRNAs play various roles in the host biological process and the life cycle of the viruses. This review summarized the circRNAs from the DNA and RNA viruses and discussed the biogenesis of viral and host circRNAs, the potential roles of viral circRNAs, and their future perspective. This review will elaborate on new insights gained on viruses encoded circRNAs during virus infection.
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