Related references
Note: Only part of the references are listed.E. coli and the etiology of human PBC: Antimitochondrial antibodies and spreading determinants
Yao Yang et al.
HEPATOLOGY (2022)
APASL clinical practice guidance: the diagnosis and management of patients with primary biliary cholangitis
Hong You et al.
HEPATOLOGY INTERNATIONAL (2022)
Effects of pemafibrate on primary biliary cholangitis with dyslipidemia
Mayumi Yamaguchi et al.
HEPATOLOGY RESEARCH (2022)
Proof-of-concept study to evaluate the safety and efficacy of saroglitazar in patients with primary biliary cholangitis
Raj Vuppalanchi et al.
JOURNAL OF HEPATOLOGY (2022)
Seladelpar improved measures of pruritus, sleep, and fatigue and decreased serum bile acids in patients with primary biliary cholangitis
Andreas E. Kremer et al.
LIVER INTERNATIONAL (2022)
Role of Immune Cells in Biliary Repair
Tian Lan et al.
FRONTIERS IN IMMUNOLOGY (2022)
Fibrates for Itch (FITCH) in Fibrosing Cholangiopathies: A Double-Blind, Randomized, Placebo-Controlled Trial
Elsemieke de Vries et al.
GASTROENTEROLOGY (2021)
A placebo-controlled randomised trial of budesonide for PBC following an insufficient response to UDCA
Gideon M. Hirschfield et al.
JOURNAL OF HEPATOLOGY (2021)
Bezafibrate therapy in primary biliary cholangitis refractory to ursodeoxycholic acid: a longitudinal study of paired liver biopsies at 5 years of follow up
Juan Antonio Sorda et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2021)
Investigational drugs in early phase development for primary biliary cholangitis
Eric M. Gochanour et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2021)
A randomized placebo-controlled trial of elafibranor in patients with primary biliary cholangitis and incomplete response to UDCA
Jorn M. Schattenberg et al.
JOURNAL OF HEPATOLOGY (2021)
Decreased infiltration of CD4+ Th1 cells indicates a good response to ursodeoxycholic acid (UDCA) in primary biliary cholangitis
Kangjie Yu et al.
PATHOLOGY RESEARCH AND PRACTICE (2021)
Association of bezafibrate with transplant-free survival in patients with primary biliary cholangitis
Atsushi Tanaka et al.
JOURNAL OF HEPATOLOGY (2021)
A Multicenter, Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Saroglitazar in Patients With Primary Biliary Cholangitis
Raj Vuppalanchi et al.
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY (2021)
Effects of Switching from Fenofibrate to Pemafibrate for Asymptomatic Primary Biliary Cholangitis
Kazufumi Dohmen et al.
KOREAN JOURNAL OF GASTROENTEROLOGY (2021)
Improved Markers of Cholestatic Liver Injury in Patients With Primary Biliary Cholangitis Treated With Obeticholic Acid and Bezafibrate
Lena Smets et al.
HEPATOLOGY (2021)
An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs
Heather J. Cordell et al.
JOURNAL OF HEPATOLOGY (2021)
The Agonists of Peroxisome Proliferator-Activated Receptor-gamma for Liver Fibrosis
Jingjing Li et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2021)
Fibrates for the treatment of pruritus in primary biliary cholangitis: a systematic review and meta-analysis
Nan Shen et al.
ANNALS OF PALLIATIVE MEDICINE (2021)
The role of GLS1-mediated glutaminolysis/2-HG/ H3K4me3 and GSH/ROS signals in Th17 responses counteracted by PPARγ agonists
Yumeng Miao et al.
THERANOSTICS (2021)
Combination of fibrates with obeticholic acid is able to normalise biochemical liver tests in patients with difficult-to-treat primary biliary cholangitis
Pierre-Antoine Soret et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2021)
Drug Therapies for Chronic Cholestatic Liver Diseases
Martin Wagner et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 60 (2020)
The Pathogenesis of Primary Biliary Cholangitis: A Comprehensive Review
Ana Lleo et al.
SEMINARS IN LIVER DISEASE (2020)
A 3-week nonalcoholic steatohepatitis mouse model shows elafibranor benefits on hepatic inflammation and cell death
Francois Briand et al.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2020)
Soluble CD163 and mannose receptor as markers of liver disease severity and prognosis in patients with primary biliary cholangitis
Lars Bossen et al.
LIVER INTERNATIONAL (2020)
Fenofibrate Improves Liver Function and Reduces the Toxicity of the Bile Acid Pool in Patients With Primary Biliary Cholangitis and Primary Sclerosing Cholangitis Who Are Partial Responders to Ursodiol
Nisanne S. Ghonem et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2020)
Integrated GWAS and mRNA Microarray Analysis Identified IFNG and CD40L as the Central Upstream Regulators in Primary Biliary Cholangitis
Kazuko Ueno et al.
HEPATOLOGY COMMUNICATIONS (2020)
Kupffer Cells Regulate Natural Killer Cells Via the NK group 2, Member D (NKG2D)/Retinoic Acid Early Inducible-1 (RAE-1) Interaction and Cytokines in a Primary Biliary Cholangitis Mouse Model
Hai-Yan Fu et al.
MEDICAL SCIENCE MONITOR (2020)
Antipruritic effect of bezafibrate and serum autotaxin measures in patients with primary biliary cholangitis
Andreas E. Kremer et al.
GUT (2019)
PPARα suppresses Th17 cell differentiation through IL-6/STAT3/RORγt pathway in experimental autoimmune myocarditis
He Chang et al.
EXPERIMENTAL CELL RESEARCH (2019)
Bezafibrate Improves GLOBE and UK-PBC Scores and Long-Term Outcomes in Patients With Primary Biliary Cholangitis
Akira Honda et al.
HEPATOLOGY (2019)
Genome-wide Association Studies of Specific Antinuclear Autoantibody Subphenotypes in Primary Biliary Cholangitis
Chan Wang et al.
HEPATOLOGY (2019)
Biochemical and plasma lipid responses to pemafibrate in patients with primary biliary cholangitis
Satoru Joshita et al.
HEPATOLOGY RESEARCH (2019)
Additional fibrate treatment in UDCA-refractory PBC patients
Sung Won Chung et al.
LIVER INTERNATIONAL (2019)
Loss of hepatic PPARα promotes inflammation and serum hyperlipidemia in diet-induced obesity
David E. Stec et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2019)
Diagnosis and Management of Primary Biliary Cholangitis
Zobair M. Younossi et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2019)
Constitutive Activation of Natural Killer Cells in Primary Biliary Cholangitis
Theresa J. Hydes et al.
FRONTIERS IN IMMUNOLOGY (2019)
B-cell-specific-peroxisome proliferator-activated receptor γ deficiency augments contact hypersensitivity with impaired regulatory B cells
Jianbing Su et al.
IMMUNOLOGY (2019)
Effectiveness of bezafibrate and ursodeoxycholic acid in patients with primary biliary cholangitis: a meta-analysis of randomized controlled trials
Rohit Agrawal et al.
ANNALS OF GASTROENTEROLOGY (2019)
The role of various peroxisome proliferator-activated receptors and their ligands in clinical practice
Giuseppe Derosa et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2018)
T Helper Cell Differentiation, Heterogeneity, and Plasticity
Jinfang Zhu
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2018)
How the biliary tree maintains immune tolerance?
Haiyan Zhang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
Environmental basis of primary biliary cholangitis
Atsushi Tanaka et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2018)
A randomized trial of obeticholic acid monotherapy in patients with primary biliary cholangitis
Kris V. Kowdley et al.
HEPATOLOGY (2018)
Implication of increased serum stromal cell-derived factor-1 for primary biliary cholangitis
Zaixing Yang et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2018)
A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis
C. Corpechot et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
PPAR-gamma activation is associated with reduced liver ischemia-reperfusion injury and altered tissue-resident macrophages polarization in a mouse model
Ivan Linares et al.
PLOS ONE (2018)
Efficacy and safety of fenofibrate add-on therapy for patients with primary biliary cholangitis and a suboptimal response to UDCA
Weijia Duan et al.
REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS (2018)
PPAR-γ Agonist Alleviates Liver and Spleen Pathology via Inducing Treg Cells during Schistosoma japonicum Infection
Yuxiao Zhu et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2018)
Activation of PPAR gamma by Curcumin protects mice from ischemia/reperfusion injury induced by orthotopic liver transplantation via modulating polarization of Kupffer cells
Yan Liu et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2018)
Increased sensitivity of Treg cells from patients with PBC to low dose IL-12 drives their differentiation into IFN-γ secreting cells
Evaggelia Liaskou et al.
JOURNAL OF AUTOIMMUNITY (2018)
The immunobiology of female predominance in primary biliary cholangitis
Alessi Gerussi et al.
JOURNAL OF AUTOIMMUNITY (2018)
Pollen Lipids Can Play a Role in Allergic Airway Inflammation
Aslog Dahl
FRONTIERS IN IMMUNOLOGY (2018)
Effects of Bezafibrate on Outcome and Pruritus in Primary Biliary Cholangitis With Suboptimal Ursodeoxycholic Acid Response
Anna Reig et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2018)
The modulation of co-stimulatory molecules by circulating exosomes in primary biliary cirrhosis
Takashi Tomiyama et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2017)
Distinct but complementary contributions of PPAR isotypes to energy homeostasis
Vanessa Dubois et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Fibrates for the treatment of cholestatic itch (FITCH): study protocol for a randomized controlled trial
Ruth Bolier et al.
TRIALS (2017)
Effect of modulation of PPAR-γ activity on Kupffer cells M1/M2 polarization in the development of non-alcoholic fatty liver disease
Wenjing Luo et al.
SCIENTIFIC REPORTS (2017)
RORγt and RORα signature genes in human Th17 cells
Glenda Castro et al.
PLOS ONE (2017)
PPARβ in macrophages and atherosclerosis
G. Chinetti-Gbaguidi et al.
BIOCHIMIE (2017)
The role and regulation of the peroxisome proliferator activated receptor alpha in human liver
Sander Kersten et al.
BIOCHIMIE (2017)
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
Jason D. Fontenot et al.
JOURNAL OF IMMUNOLOGY (2017)
Combined ursodeoxycholic acid (UDCA) and fenofibrate in primary biliary cholangitis patients with incomplete UDCA response may improve outcomes
A. C. Cheung et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2016)
Elevated circulating CD14lowCD16+ monocyte subset in primary biliary cirrhosis correlates with liver injury and promotes Th1 polarization
Anping Peng et al.
CLINICAL AND EXPERIMENTAL MEDICINE (2016)
Peroxisome proliferator-activated receptor alpha deficiency impairs regulatory T cell functions: Possible application in the inhibition of melanoma tumor growth in mice
Aziz Hichami et al.
BIOCHIMIE (2016)
Long-Term Fenofibrate Treatment in Primary Biliary Cholangitis Improves Biochemistry but Not the UK-PBC Risk Score
Vinod S. Hegade et al.
DIGESTIVE DISEASES AND SCIENCES (2016)
Regulation of germinal center B-cell differentiation
Yang Zhang et al.
IMMUNOLOGICAL REVIEWS (2016)
Gender-specific differences in PPARγ regulation of follicular helper T cell responses with estrogen
Hong-Jai Park et al.
SCIENTIFIC REPORTS (2016)
The Role of PPAR gamma in Cardiovascular Diseases
M. Kvandova et al.
PHYSIOLOGICAL RESEARCH (2016)
A Prospective Randomized Controlled Study of Long-Term Combination Therapy Using Ursodeoxycholic Acid and Bezafibrate in Patients With Primary Biliary Cirrhosis and Dyslipidemia
Kenichi Hosonuma et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2015)
Treatment in vitro with PPARα and PPARγ ligands drives M1-to-M2 polarization of macrophages from T. cruzi-infected mice
Federico Penas et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Ciglitazone, a Peroxisome Proliferator-Activated Receptor Gamma Ligand, Inhibits Proliferation and Differentiation of Th17 Cells
Dong Hyeok Kim et al.
BIOMOLECULES & THERAPEUTICS (2015)
Animal Models of Primary Biliary Cirrhosis
Tomohiro Katsumi et al.
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2015)
Efficacy of Obeticholic Acid in Patients With Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid
Gideon M. Hirschfield et al.
GASTROENTEROLOGY (2015)
CXCR5+ CD4+ T Follicular Helper Cells Participate in the Pathogenesis of Primary Biliary Cirrhosis
Lifeng Wang et al.
HEPATOLOGY (2015)
Fibrates and cholestasis
Nisanne S. Ghonem et al.
HEPATOLOGY (2015)
Antagonizing Peroxisome Proliferator-Activated Receptor α Activity Selectively Enhances Th1 Immunity in Male Mice
Monan Angela Zhang et al.
JOURNAL OF IMMUNOLOGY (2015)
Docosahexaenoic acid induces M2 macrophage polarization through peroxisome proliferator-activated receptor γ activation
Hae Yeun Chang et al.
LIFE SCIENCES (2015)
Fenofibrate is effective adjunctive therapy in the treatment of primary biliary cirrhosis: A meta-analysis
Alla Y. Grigorian et al.
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY (2015)
Increased Numbers of Circulating ICOS+ Follicular Helper T and CD38+ Plasma Cells in Patients with Newly Diagnosed Primary Biliary Cirrhosis
Li Wang et al.
DIGESTIVE DISEASES AND SCIENCES (2015)
Combination therapy of bezafibrate and ursodeoxycholic acid for primary biliary cirrhosis: A meta-analysis
Yan Zhang et al.
HEPATOLOGY RESEARCH (2015)
Biochemical responses to bezafibrate improve long-term outcome in asymptomatic patients with primary biliary cirrhosis refractory to UDCA
Atsushi Tanaka et al.
JOURNAL OF GASTROENTEROLOGY (2015)
Bezafibrate normalizes alkaline phosphatase in primary biliary cirrhosis patients with incomplete response to ursodeoxycholic acid
Sabela Lens et al.
LIVER INTERNATIONAL (2014)
PPARγ Negatively Regulates T Cell Activation to Prevent Follicular Helper T Cells and Germinal Center Formation
Hong-Jai Park et al.
PLOS ONE (2014)
B-Cell Depletion With Rituximab in Patients With Primary Biliary Cirrhosis Refractory to Ursodeoxycholic Acid
Robert P. Myers et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2013)
Clinical significance of the fluctuation of primary biliary cirrhosis-related autoantibodies during the course of the disease
Nikolaos K. Gatselis et al.
AUTOIMMUNITY (2013)
BAFF promotes regulatory T-cell apoptosis and blocks cytokine production by activating B cells in primary biliary cirrhosis
Bo Zhang et al.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2013)
PPAR-Gamma in Ulcerative Colitis: A Novel Target for Intervention
Benjamin Bertin et al.
CURRENT DRUG TARGETS (2013)
Anticholestatic Effects of Bezafibrate in Patients with Primary Biliary Cirrhosis Treated with Ursodeoxycholic Acid
Akira Honda et al.
HEPATOLOGY (2013)
PPARγ ligand attenuates portal inflammation in the MRL-lpr mouse: a new strategy to restrain cholangiopathy in primary biliary cirrhosis
Yusuke Nozaki et al.
MEDICAL MOLECULAR MORPHOLOGY (2013)
T follicular helper cell diversity and plasticity
Jennifer L. Cannons et al.
TRENDS IN IMMUNOLOGY (2013)
Immunoglobulin M levels inversely correlate with CD40 ligand promoter methylation in patients with primary biliary cirrhosis
Ana Lleo et al.
HEPATOLOGY (2012)
15-deoxy-Δ12,14-prostaglandin J2 reduces recruitment of bone marrow-derived monocyte/macrophages in chronic liver injury in mice
Zhen Han et al.
HEPATOLOGY (2012)
Biochemical and immunologic effects of rituximab in patients with primary biliary cirrhosis and an incomplete response to ursodeoxycholic acid
Masanobu Tsuda et al.
HEPATOLOGY (2012)
Efficacy of fenofibrate in Chinese patients with primary biliary cirrhosis partially responding to ursodeoxycholic acid therapy
Xiao Feng Han et al.
JOURNAL OF DIGESTIVE DISEASES (2012)
Peroxisome proliferator-activated receptor (PPAR)α and -γ regulate IFNγ and IL-17A production by human T cells in a sex-specific way
Monan Angela Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Fenofibrate Enhances the In Vitro Differentiation of Foxp3+ Regulatory T Cells in Mice
Zhou Zhou et al.
PPAR RESEARCH (2012)
Pilot study: fenofibrate for patients with primary biliary cirrhosis and an incomplete response to ursodeoxycholic acid
C. Levy et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2011)
Role of NKT cells in autoimmune liver disease
Tania Santodomingo-Garzon et al.
AUTOIMMUNITY REVIEWS (2011)
Regulation of dectin-1-mediated dendritic cell activation by peroxisome proliferator-activated receptor-gamma ligand troglitazone
Grethe Kock et al.
BLOOD (2011)
PPARδ deficient mice develop elevated Th1/Th17 responses and prolonged experimental autoimmune encephalomyelitis
Saravanan Kanakasabai et al.
BRAIN RESEARCH (2011)
Innate Immunity and Primary Biliary Cirrhosis: Activated Invariant Natural Killer T Cells Exacerbate Murine Autoimmune Cholangitis and Fibrosis
Si-Jie Wu et al.
HEPATOLOGY (2011)
Additive improvement induced by bezafibrate in patients with primary biliary cirrhosis showing refractory response to ursodeoxycholic acid
Yasuto Takeuchi et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2011)
Peroxisome Proliferator-Activated Receptor γ-Regulated Cathepsin D Is Required for Lipid Antigen Presentation by Dendritic Cells
Britt Nakken et al.
JOURNAL OF IMMUNOLOGY (2011)
Significance of periductal Langerhans cells and biliary epithelial cell-derived macrophage inflammatory protein-3α in the pathogenesis of primary biliary cirrhosis
Kenichi Harada et al.
LIVER INTERNATIONAL (2011)
Altered biliary epithelial cell and monocyte responses to lipopolysaccharide as a TLR ligand in patients with primary biliary cirrhosis
Jingmin Zhao et al.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2011)
Functional and Clinical Aspects of the B-Cell-Activating Factor (BAFF): A Narrative Review
G. A. Lied et al.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2011)
Peroxisome proliferator-activated receptor δ agonists inhibit T helper type 1 (Th1) and Th17 responses in experimental allergic encephalomyelitis
Saravanan Kanakasabai et al.
IMMUNOLOGY (2010)
Peroxisome proliferator-activated receptor δ limits the expansion of pathogenic Th cells during central nervous system autoimmunity
Shannon E. Dunn et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Peroxisome Proliferator-Activated Receptor a and g Agonists Together with TGF-β Convert Human CD4+CD25- T Cells into Functional Foxp3+ Regulatory T Cells
Jin Lei et al.
JOURNAL OF IMMUNOLOGY (2010)
Fenofibrate in Primary Biliary Cirrhosis: A Pilot Study
E. N. Liberopoulos et al.
OPEN CARDIOVASCULAR MEDICINE JOURNAL (2010)
Periductal interleukin-17 production in association with biliary innate immunity contributes to the pathogenesis of cholangiopathy in primary biliary cirrhosis
K. Harada et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2009)
Hepatic IL-17 responses in human and murine primary biliary cirrhosis
Ruth Y. Z. Lan et al.
JOURNAL OF AUTOIMMUNITY (2009)
The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity
Luisa Klotz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Alternative M2 activation of Kupffer cells by PPARδ ameliorates obesity-induced insulin resistance
Justin I. Odegaard et al.
CELL METABOLISM (2008)
Repression of interferon-gamma expression in T cells by Prospero-related Homeobox protein
Linfang Wang et al.
CELL RESEARCH (2008)
The efficacy of ursodeoxycholic acid and bezafibrate combination therapy for primary biliary cirrhosis: A prospective, multicenter study
Shinji Iwasaki et al.
HEPATOLOGY RESEARCH (2008)
Natural killer T cells exacerbate liver injury in a transforming growth factor β receptor II dominant-negative mouse model of primary biliary cirrhosis
Ya-Hui Chuang et al.
HEPATOLOGY (2008)
Exploring the full spectrum of macrophage activation
David M. Mosser et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Altered expression of TLR homolog RP105 on monocytes hypersensitive to LPS in patients with primary biliary cirrhosis
Yutaka Honda et al.
JOURNAL OF HEPATOLOGY (2007)
Interleukin-10 is upregulated by nanomolar rosiglitazone treatment of mature dendritic cells and human CD4+T cells
Paul W. Thompson et al.
CYTOKINE (2007)
Peroxisome proliferator-activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell-mediated autoimmunity
Shannon E. Dunn et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Peroxisome proliferator-activated receptor γ control of dendritic cell function contributes to development of CD4+ T cell anergy
Luisa Klotz et al.
JOURNAL OF IMMUNOLOGY (2007)
Differentiation of CD1a- and CD1a+ monocyte-derived dendritic cells is biased by lipid environment and PPARγ
Peter Gogolak et al.
BLOOD (2007)
Increased killing activity and decreased cytokine production in NK cells in patients with primary biliary cirrhosis
Ya-Hui Chuang et al.
JOURNAL OF AUTOIMMUNITY (2006)
Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-κB and -MAPK signaling pathways
T Yokoyama et al.
LIVER INTERNATIONAL (2006)
Peroxisome proliferator-activated receptor α, δ, γ1 and γ2 expressions are present in human monocyte-derived dendritic cells and modulate dendritic cell maturation by addition of subtype-specific ligands
MA Jakobsen et al.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2006)
Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis
RY Lan et al.
HEPATOLOGY (2006)
Nuclear receptors and autoimmune disease: The potential of PPAR agonists to treat multiple sclerosis
MK Racke et al.
JOURNAL OF NUTRITION (2006)
Bezafibrate may attenuate biliary damage associated with chronic liver diseases accompanied by high serum biliary enzyme levels
Ryuichi Kita et al.
JOURNAL OF GASTROENTEROLOGY (2006)
PPAR-γ agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-κB pathways
S Appel et al.
BLOOD (2005)
Protective effect of pioglitazone against endotoxin-induced liver injury through prevention of Kupffer cell sensitization
N Enomoto et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2005)
Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis
TK Mao et al.
HEPATOLOGY (2005)
Hepatic expression of toll-like receptor 4 in primary biliary cirrhosis
AP Wang et al.
JOURNAL OF AUTOIMMUNITY (2005)
Th1 cytokine-induced downregulation of PPARγ in human biliary cells relates to cholangitis in primary biliary cirrhosis
K Harada et al.
HEPATOLOGY (2005)
A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse
AJ Robe et al.
HEPATOLOGY (2005)
Fractalkine and CX3CR1 are involved in the recruitment of Intraepithelial lymphocytes of intrahepatic bile ducts
K Isse et al.
HEPATOLOGY (2005)
Primary biliary cirrhosis in monozygotic and dizygotic twins: Genetics, epigenetics, and environment
C Selmi et al.
GASTROENTEROLOGY (2004)
Activation of PPARγ specifies a dendritic cell subtype capable of enhanced induction of iNKT cell expansion
I Szatmari et al.
IMMUNITY (2004)
Peroxisome proliferator-activated receptor-γ and its ligands attenuate biologic functions of human natural killer cells
X Zhang et al.
BLOOD (2004)
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
WJ Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Accumulating CD57+ CD3+ natural killer T cells are related to intrahepatic bile duct lesions in primary biliary cirrhosis
K Harada et al.
LIVER INTERNATIONAL (2003)
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
JD Fontenot et al.
NATURE IMMUNOLOGY (2003)
Bezafibrate treatment: a new medical approach for PBC patients?
T Kanda et al.
JOURNAL OF GASTROENTEROLOGY (2003)
Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human mid tetramer
H Kita et al.
GASTROENTEROLOGY (2002)
Dendritic cell immunogenicity is regulated by peroxisome proliferator-activated receptor γ
A Nencioni et al.
JOURNAL OF IMMUNOLOGY (2002)
Fibrates suppress chenodeoxycholic acid-induced RANTES expression through inhibition of NF-κB activation
Y Hirano et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
Dendritic cell subtypes in autoimmune liver diseases; decreased expression of HLA DR and CD123 on type 2 dendritic cells
Y Hiasa et al.
HEPATOLOGY RESEARCH (2002)
Interleukin (IL-4) indirectly suppresses IL-2 production by human T lymphocytes via peroxisome proliferator-activated receptor γ activated by macrophage-derived 12/15-lipoxygenase ligands
XY Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Detection of serum nitrite and nitrate in primary biliary cirrhosis: Possible role of nitric oxide in bile duct injury
A Hokari et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2002)
Effect of bezafibrate in primary biliary cirrhosis: a pilot study
K Ohmoto et al.
LIVER (2001)
Activation of retinoic X receptor and peroxisome proliferator-activated receptor-gamma inhibits nitric oxide and tumor necrosis factor-alpha production in rat Kupffer cells
K Uchimura et al.
HEPATOLOGY (2001)
Effect of bezafibrate in the treatment of primary biliary cirrhosis
T Kurihara et al.
CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL (2000)