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BLOOD (2010)
Vaccine Adjuvants: Putting Innate Immunity to Work
Robert L. Coffman et al.
IMMUNITY (2010)
Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells
Annabell Bachem et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Defective Cross-Presentation of Viral Antigens in GILT-Free Mice
Reshma Singh et al.
SCIENCE (2010)
Bacteria-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity
Fabiana Saccheri et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
A Role for Lipid Bodies in the Cross-presentation of Phagocytosed Antigens by MHC Class I in Dendritic Cells
Laurence Bougneres et al.
IMMUNITY (2009)
The Small GTPase Rac2 Controls Phagosomal Alkalinization and Antigen Crosspresentation Selectively in CD8+ Dendritic Cells
Ariel Savina et al.
IMMUNITY (2009)
Regulation of the immune response by stress-activated protein kinases
Mercedes Rincon et al.
IMMUNOLOGICAL REVIEWS (2009)
ISCOMATRIX Adjuvant Induces Efficient Cross-Presentation of Tumor Antigen by Dendritic Cells via Rapid Cytosolic Antigen Delivery and Processing via Tripeptidyl Peptidase II
Max Schnurr et al.
JOURNAL OF IMMUNOLOGY (2009)
AS04, an Aluminum Salt- and TLR4 Agonist-Based Adjuvant System, Induces a Transient Localized Innate Immune Response Leading to Enhanced Adaptive Immunity
Arnaud M. Didierlaurent et al.
JOURNAL OF IMMUNOLOGY (2009)
IRAP Identifies an Endosomal Compartment Required for MHC Class I Cross-Presentation
Loredana Saveanu et al.
SCIENCE (2009)
The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement
Irina Caminschi et al.
BLOOD (2008)
Recruitment of Rab27a to Phagosomes Controls Microbial Antigen Cross-Presentation by Dendritic Cells
Seong Hyun Kim et al.
INFECTION AND IMMUNITY (2008)
Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin
David Sancho et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
Mirjam Kool et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
The adjuvants aluminum hydroxide and MF59 induce monocyte and granulocyte chemoattractants and enhance monocyte differentiation toward dendritic cells
Anja Seubert et al.
JOURNAL OF IMMUNOLOGY (2008)
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
You-Me Kim et al.
NATURE (2008)
Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I
Tiziana Di Pucchio et al.
NATURE IMMUNOLOGY (2008)
Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation
Sven Burgdorf et al.
NATURE IMMUNOLOGY (2008)
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
Veit Hornung et al.
NATURE IMMUNOLOGY (2008)
Toll-like receptor 9 (TLR9) agonists in the treatment of cancer
A. M. Krieg
ONCOGENE (2008)
Molecular and cellular signatures of human vaccine adjuvants
F. Mosca et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset
Ming Lee Lin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity
Kai Hildner et al.
SCIENCE (2008)
Alum boosts TH2-type antibody responses to whole-inactivated virus influenza vaccine in mice but does not confer superior protection
Laura Bungener et al.
VACCINE (2008)
Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells
Alessandra Giodini et al.
EMBO JOURNAL (2008)
MF59 is a safe and potent vaccine adjuvant that enhances protection against influenza virus infection
Derek T. O'Hagan
EXPERT REVIEW OF VACCINES (2007)
Antigen crosspresentation by human plasmacytoid dendritic cells
Guillaume Hoeffel et al.
IMMUNITY (2007)
Functional gap junctions facilitate melanoma antigen transfer and cross-presentation between human dendritic cells
Ariadna Mendoza-Naranjo et al.
JOURNAL OF IMMUNOLOGY (2007)
Development of TLR9 agonists for cancer therapy
Arthur M. Krieg
JOURNAL OF CLINICAL INVESTIGATION (2007)
Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes
Carolina Jancic et al.
NATURE CELL BIOLOGY (2007)
New hepatitis B vaccine formulated with an improved adjuvant system
Michael Kundi
EXPERT REVIEW OF VACCINES (2007)
Differential antigen processing by dendritic cell subsets in vivo
Diana Dudziak et al.
SCIENCE (2007)
NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells
Ariel Savina et al.
CELL (2006)
Toll-dependent selection of microbial antigens for presentation by dendritic cells
JM Blander et al.
NATURE (2006)
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
K Tabeta et al.
NATURE IMMUNOLOGY (2006)
Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivo
D Accapezzato et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Differential lysosomal proteolysis in antigen-presenting CeRs determines antigen fate
L Delamarre et al.
SCIENCE (2005)
Cross-presentation by intercellular peptide transfer through gap junctions
J Neijssen et al.
NATURE (2005)
Activation and signaling of the p38 MAP kinase pathway
T Zarubin et al.
CELL RESEARCH (2005)
Dendritic cells cross-present HIV antigens from live as well as apoptotic infected CD4+ T lymphocytes
C Marañón et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
E Latz et al.
NATURE IMMUNOLOGY (2004)
Control of cross-presentation during dendritic cell maturation
BC Gil-Torregrosa et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2004)
Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo
LJ Shen et al.
IMMUNITY (2004)
Liposome-encapsulated CpG oligodeoxynucleotides as a potent adjuvant for inducing type 1 innate immunity
Y Suzuki et al.
CANCER RESEARCH (2004)
Role of c-Jun N-terminal kinase on lipopolysaccharide induced maturation of human monocyte-derived dendritic cells
T Nakahara et al.
INTERNATIONAL IMMUNOLOGY (2004)
Results of clinical trials with an allogeneic melanoma tumor cell lysate vaccine: Melacine((R))
VK Sondak et al.
SEMINARS IN CANCER BIOLOGY (2003)
Antibody responses in sheep vaccinated against Staphylococcus aureus mastitis:: A comparison of two experimental vaccines containing different adjuvants
T Tollersrud et al.
VETERINARY RESEARCH COMMUNICATIONS (2002)
Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model
K Heckelsmiller et al.
JOURNAL OF IMMUNOLOGY (2002)
Analysis of protease activity in live antigen-presenting cells shows regulation of the phagosomal proteolytic contents during dendritic cell activation
AM Lennon-Duménil et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
The cell biology of MHC class I antigen presentation
A Williams et al.
TISSUE ANTIGENS (2002)
A hepatitis B vaccine formulated with a novel adjuvant system
F Ambrosch et al.
VACCINE (2000)