Related references
Note: Only part of the references are listed.CRISPR/Cas9-mediated demethylation of FOXP3-TSDR toward Treg-characteristic programming of Jurkat T cells
Camilla Wilk et al.
CELLULAR IMMUNOLOGY (2022)
Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes
Yuk-Fun Liu et al.
DIABETES (2022)
CTLA-4 gene mutation and multiple sclerosis: A case report and literature review
Ting-Wei Lin et al.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2022)
Knockdown of lncRNA HAGLR promotes Treg cell differentiation through increasing the RUNX3 level in dermatomyositis
Wang Yan et al.
JOURNAL OF MOLECULAR HISTOLOGY (2022)
microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function
Wei-Le Wang et al.
PLOS BIOLOGY (2022)
Characterization of chromatin accessibility in psoriasis
Zheng Zhang et al.
FRONTIERS OF MEDICINE (2022)
TCR-T Immunotherapy: The Challenges and Solutions
Yating Liu et al.
FRONTIERS IN ONCOLOGY (2022)
MicroRNA-31 regulates T-cell metabolism via HIF1α and promotes chronic GVHD pathogenesis in mice
Yongxia Wu et al.
Blood Advances (2022)
The FOXP3 full-length isoform controls the lineage-stability of CD4+FOXP3+ regulatory T cells
Christina Seitz et al.
CLINICAL IMMUNOLOGY (2022)
Kidney GATA3+ regulatory T cells play roles in the convalescence stage after antibody-mediated renal injury
Ryota Sakai et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2021)
Administration of CD4+CD25highCD127-FoxP3+ Regulatory T Cells for Relapsing-Remitting Multiple Sclerosis: A Phase 1 Study
Kamil Chwojnicki et al.
BIODRUGS (2021)
Reduction of peripheral regulatory T cells in active rheumatoid arthritis patients with coronary artery disease
Yanyan Wang et al.
BMC IMMUNOLOGY (2021)
Exosomes derived from thymic stromal lymphopoietin-treated dendritic cells regulate T helper 17/regulatory T cell differentiation via miR-21/Smad7 axis
Qingshan Ji et al.
EXPERIMENTAL CELL RESEARCH (2021)
MicroRNA-21-5p protects melanocytes via targeting STAT3 and modulating Treg/Teff balance to alleviate vitiligo
Jing Huo et al.
MOLECULAR MEDICINE REPORTS (2021)
Gut Microbiota May Play a Significant Role in the Pathogenesis of Graves' Disease
Wen Jiang et al.
THYROID (2021)
Targeted De-Methylation of the FOXP3-TSDR Is Sufficient to Induce Physiological FOXP3 Expression but Not a Functional Treg Phenotype
Christopher Kressler et al.
FRONTIERS IN IMMUNOLOGY (2021)
A STAT3 inhibitor ameliorates CNS autoimmunity by restoring Teff:Treg balance
Saba Aqel et al.
JCI INSIGHT (2021)
The TGF-β/miR-31/CEACAM1-S axis inhibits CD4+CD25+ Treg differentiation in systemic lupus erythematosus
Yanjuan Liu et al.
IMMUNOLOGY AND CELL BIOLOGY (2021)
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid
McLane J. Watson et al.
NATURE (2021)
Super-Treg: Toward a New Era of Adoptive Treg Therapy Enabled by Genetic Modifications
Leila Amini et al.
FRONTIERS IN IMMUNOLOGY (2021)
Celiac Disease Causes Epithelial Disruption and Regulatory T Cell Recruitment in the Oral Mucosa
Javier Sanchez-Solares et al.
FRONTIERS IN IMMUNOLOGY (2021)
Evolving Antibody Therapies for the Treatment of Type 1 Diabetes
Qi Ke et al.
FRONTIERS IN IMMUNOLOGY (2021)
Control of Foxp3 induction and maintenance by sequential histone acetylation and DNA demethylation
Jun Li et al.
CELL REPORTS (2021)
The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes
Carolin Wiechers et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2021)
Polyclonal Regulatory T Cell Manufacturing Under cGMP: A Decade of Experience
Joanna Balcerek et al.
FRONTIERS IN IMMUNOLOGY (2021)
MicroRNA-21 Regulates Diametrically Opposed Biological Functions of Regulatory T Cells
Jijun Sun et al.
FRONTIERS IN IMMUNOLOGY (2021)
Co-Expression of FOXP3FL and FOXP3Δ2 Isoforms Is Required for Optimal Treg-Like Cell Phenotypes and Suppressive Function
Yohei Sato et al.
FRONTIERS IN IMMUNOLOGY (2021)
IL-6 and TNFα Drive Extensive Proliferation of Human Tregs Without Compromising Their Lineage Stability or Function
Nikolaos Skartsis et al.
FRONTIERS IN IMMUNOLOGY (2021)
Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells
Ryoji Kawakami et al.
IMMUNITY (2021)
A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance
Stanislav Dikiy et al.
IMMUNITY (2021)
IL-6 receptor blockade does not slow beta cell loss in new-onset type 1 diabetes
Carla J. Greenbaum et al.
JCI INSIGHT (2021)
Strong Expansion of Human Regulatory T Cells for Adoptive Cell Therapy Results in Epigenetic Changes Which May Impact Their Survival and Function
Kristy Ou et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
CAR- and TRuC-redirected regulatory T cells differ in capacity to control adaptive immunity to FVIII
Jyoti Rana et al.
MOLECULAR THERAPY (2021)
Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations
David Zemmour et al.
NATURE IMMUNOLOGY (2021)
The roles of Polycomb repressive complexes in mammalian development and cancer
Andrea Piunti et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)
PPARγ marks splenic precursors of multiple nonlymphoid-tissue Treg compartments
Chaoran Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation
Gerdien Mijnheer et al.
NATURE COMMUNICATIONS (2021)
Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen
Viola L. Boccasavia et al.
CELL REPORTS (2021)
Antigenic Challenge Influences Epigenetic Changes in Antigen-Specific T Regulatory Cells
Dorota Iwaszkiewicz-Grzes et al.
FRONTIERS IN IMMUNOLOGY (2021)
A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells
Harikesh S. Wong et al.
CELL (2021)
Foxp3 enhancers synergize to maximize regulatory T cell suppressive capacity
Xinying Zong et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2021)
MiR-206 regulates the Th17/Treg ratio during osteoarthritis
Xiguang Ye et al.
MOLECULAR MEDICINE (2021)
A comprehensive integrated post-GWAS analysis of Type 1 diabetes reveals enhancer-based immune dysregulation
Seung-Soo Kim et al.
PLOS ONE (2021)
The effect of low-dose IL-2 and Treg adoptive cell therapy in patients with 1 diabetes
Shen Dong et al.
JCI INSIGHT (2021)
Tissue Tregs and Maintenance of Tissue Homeostasis
Qing Shao et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Type I interferons induce peripheral T regulatory cell differentiation under tolerogenic conditions
Sara Vitale et al.
INTERNATIONAL IMMUNOLOGY (2021)
T-regulatory cells from patients with rheumatoid arthritis retain suppressor functions in vitro
Daniil Shevyrev et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2021)
Immunomodulation Followed by Antigen-Specific Treg Infusion Controls Islet Autoimmunity
Cecilia Cabello-Kindelan et al.
DIABETES (2020)
Type 1 diabetes linked PTPN22 gene polymorphism is associated with the frequency of circulating regulatory T cells
Milla Valta et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2020)
Genetic Variation in Type 1 Diabetes Reconfigures the 3D Chromatin Organization of T Cells and Alters Gene Expression
Maria Fasolino et al.
IMMUNITY (2020)
Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF
Michael Delacher et al.
IMMUNITY (2020)
EZH2 deficiency attenuates Treg differentiation in rheumatoid arthritis
Xin-yue Xiao et al.
JOURNAL OF AUTOIMMUNITY (2020)
miR-133a-3p/FOXP3 axis regulates cell proliferation and autophagy in gastric cancer
Jia-Peng Li et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2020)
Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases
Naganari Ohkura et al.
IMMUNITY (2020)
Non-Coding RNAs in CD4+ T Cells: New Insights Into the Pathogenesis of Systemic Lupus Erythematosus
Xiaofei Gao et al.
FRONTIERS IN IMMUNOLOGY (2020)
Large-Scale Generation of Human Allospecific Induced Tregs With Functional Stability for Use in Immunotherapy in Transplantation
Evelyn Katy Alvarez-Salazar et al.
FRONTIERS IN IMMUNOLOGY (2020)
Low-dose IL-2 in children with recently diagnosed type 1 diabetes: a Phase I/II randomised, double-blind, placebo-controlled, dose-finding study
Michelle Rosenzwajg et al.
DIABETOLOGIA (2020)
Regulatory T cells in patients with early untreated rheumatoid arthritis: Phenotypic changes in the course of methotrexate treatment
Anastasia Avdeeva et al.
BIOCHIMIE (2020)
miR-155 antagomir protect against DSS-induced colitis in mice through regulating Th17/Treg cell balance by Jarid2/Wnt/β-catenin
Feng Zhu et al.
BIOMEDICINE & PHARMACOTHERAPY (2020)
Gene editing to induce FOXP3 expression in human CD4+ T cells leads to a stable regulatory phenotype and function
Yuchi Honaker et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
Gut Dysbiosis Contributes to the Imbalance of Treg and Th17 Cells in Graves' Disease Patients by Propionic Acid
Xinhuan Su et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2020)
Functional CRISPR dissection of gene networks controlling human regulatory T cell identity
Kathrin Schumann et al.
NATURE IMMUNOLOGY (2020)
An IL-2 mutein engineered to promote expansion of regulatory T cells arrests ongoing autoimmunity in mice
Liliane Khoryati et al.
SCIENCE IMMUNOLOGY (2020)
Engineered regulatory T cells expressing myelin-specific chimeric antigen receptors suppress EAE progression
Alessandra De Paula Pohl et al.
CELLULAR IMMUNOLOGY (2020)
T-reg cell-based therapies: challenges and perspectives
Caroline Raffin et al.
NATURE REVIEWS IMMUNOLOGY (2020)
A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells
Frederic Van Gool et al.
IMMUNITY (2019)
Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation
Ricardo J. Miragaia et al.
IMMUNITY (2019)
Immune- and non-immune-mediated roles of regulatory T-cells during wound healing
Dietmar M. Zaiss et al.
IMMUNOLOGY (2019)
The FOXP3Δ2 isoform supports Treg cell development and protects against severe IPEX syndrome
Katie Frith et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)
Risk variants disrupting enhancers of TH1 and TREG cells in type 1 diabetes
Peng Gao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation
Garima Garg et al.
CELL REPORTS (2019)
NF-κB-driven miR-34a impairs Treg/Th17 balance via targeting Foxp3
Mengxiao Xie et al.
JOURNAL OF AUTOIMMUNITY (2019)
Cellular functions of long noncoding RNAs
Run-Wen Yao et al.
NATURE CELL BIOLOGY (2019)
Blockade of miR-142-3p promotes anti-apoptotic and suppressive function by inducing KDM6A-mediated H3K27me3 demethylation in induced regulatory T cells
Ji Gao et al.
CELL DEATH & DISEASE (2019)
Regulatory T cells engineered with a novel insulin-specific chimeric antigen receptor as a candidate immunotherapy for type 1 diabetes
Michel Tenspolde et al.
JOURNAL OF AUTOIMMUNITY (2019)
Helios Deficiency Predisposes the Differentiation of CD4+Foxp3- T Cells into Peripherally Derived Regulatory T Cells
Mathias Skadow et al.
JOURNAL OF IMMUNOLOGY (2019)
Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response
Patrick A. Baeuerle et al.
NATURE COMMUNICATIONS (2019)
Transcription Factor IRF4 Dysfunction Affects the Immunosuppressive Function of Treg Cells in Patients with Primary Immune Thrombocytopenia
Meiwen Tang et al.
BIOMED RESEARCH INTERNATIONAL (2019)
Anti-CD3 Antibody for the Prevention of Type 1 Diabetes: A Story of Perseverance
Jason Gaglia et al.
BIOCHEMISTRY (2019)
TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity
Xiang Sun et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Long non-coding RNA DQ786243 modulates the induction and function of CD4+ Treg cells through Foxp3-miR-146a-NF-κB axis: Implications for alleviating oral lichen planus
Jing Wang et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
Thymically-derived Foxp3+ regulatory T cells are the primary regulators of type 1 diabetes in the non-obese diabetic mouse model
Daniel R. Holohan et al.
PLOS ONE (2019)
MiR-21 Participates in the PD-1/PD-L1 Pathway-Mediated Imbalance of Th17/Treg Cells in Patients After Gastric Cancer Resection
Xiaoyu Zheng et al.
ANNALS OF SURGICAL ONCOLOGY (2019)
Immunological and clinical effects of low-dose interleukin-2 across 11 autoimmune diseases in a single, open clinical trial
Michelle Rosenzwajg et al.
ANNALS OF THE RHEUMATIC DISEASES (2019)
Novel small molecule IL-6 inhibitor suppresses autoreactive Th17 development and promotes Treg development
S. I. Aqel et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2019)
Type 1 Diabetes in STAT Protein Family Mutations: Regulating the Th17/Treg Equilibrium and Beyond
Marco Fabbri et al.
DIABETES (2019)
Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function
Catherine Konopacki et al.
NATURE IMMUNOLOGY (2019)
Homeobox protein Hhex negatively regulates Treg cells by inhibiting Foxp3 expression and function
Sung Woong Jang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes
Martin G. Scherm et al.
NATURE COMMUNICATIONS (2019)
1,25-Dihydroxyvitamin D3 Ameliorates Collagen-Induced Arthritis via Suppression of Th17 Cells Through miR-124 Mediated Inhibition of IL-6 Signaling
Li Zhou et al.
FRONTIERS IN IMMUNOLOGY (2019)
Treg gene signatures predict and measure type 1 diabetes trajectory
Anne M. Pesenacker et al.
JCI INSIGHT (2019)
Bim regulates the survival and suppressive capability of CD8+ FOXP3+ regulatory T cells during murine GVHD
Kimberle Agle et al.
BLOOD (2018)
TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype
Chaoran Li et al.
CELL (2018)
Peripherally induced regulatory T cells contribute to the control of autoimmune diabetes in the NOD mouse model
Cornelia Schuster et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2018)
FoxP3 isoforms and PD-1 expression by T regulatory cells in multiple sclerosis
Manolo Sambucci et al.
SCIENTIFIC REPORTS (2018)
Maresin 1 improves the Treg/Th17 imbalance in rheumatoid arthritis through miR-21
Shengwei Jin et al.
ANNALS OF THE RHEUMATIC DISEASES (2018)
Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy
Jamie B. Spangler et al.
JOURNAL OF IMMUNOLOGY (2018)
Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes
Harm-Jan Westra et al.
NATURE GENETICS (2018)
CTLA-4+49 G/A, a functional T1D risk SNP, affects CTLA-4 level in Treg subsets and IA-2A positivity, but not beta-cell function
Yang Chen et al.
SCIENTIFIC REPORTS (2018)
A Unique Population: Adipose-Resident Regulatory T Cells
Qin Zeng et al.
FRONTIERS IN IMMUNOLOGY (2018)
Regulatory T-cell therapy for autoimmune and autoinflammatory diseases: The next frontier
Jonathan H. Esensten et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)
A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease
Laurence B. Peterson et al.
JOURNAL OF AUTOIMMUNITY (2018)
Thymus-derived Foxp3+ regulatory T cells upregulate RORt expression under inflammatory conditions
Juhao Yang et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2018)
Interleukin 2 modulates thymic-derived regulatory T cell epigenetic landscape
Laurent Chorro et al.
NATURE COMMUNICATIONS (2018)
Clinical, Immunological, and Molecular Heterogeneity of 173 Patients With the Phenotype of Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked (IPEX) Syndrome
Eleonora Gambineri et al.
FRONTIERS IN IMMUNOLOGY (2018)
Serum microRNA Profiles Serve as Novel Biomarkers for Autoimmune Diseases
Fangfang Jin et al.
FRONTIERS IN IMMUNOLOGY (2018)
Transcriptional regulation and development of regulatory T cells
Wonyong Lee et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2018)
Regulatory T cells and skeletal muscle regeneration
Stefano Schiaffino et al.
FEBS JOURNAL (2017)
Pre-diagnostic genotyping identifies TID subjects with impaired Treg IL-2 signaling and an elevated proportion of FOXP3+IL-17+ cells
A. K. Marwaha et al.
GENES AND IMMUNITY (2017)
Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells
Norihito Hayatsu et al.
IMMUNITY (2017)
Induction and maintenance of regulatory T cells by transcription factors and epigenetic modifications
Mana Iizuka-Koga et al.
JOURNAL OF AUTOIMMUNITY (2017)
Stability and function of regulatory T cells expressing the transcription factor T-bet
Andrew G. Levine et al.
NATURE (2017)
Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity
David Zemmour et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Ash1l and lnc-Smad3 coordinate Smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity
Meng Xia et al.
NATURE COMMUNICATIONS (2017)
Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos
Shoji Maenohara et al.
PLOS GENETICS (2017)
The Microbiota and epigenetic Regulation of T Helper 17/Regulatory T Cells: in Search of a Balanced immune System
Annie Luo et al.
FRONTIERS IN IMMUNOLOGY (2017)
Novel Senescent Regulatory T-Cell Subset with Impaired Suppressive Function in Rheumatoid Arthritis
Johannes Fessler et al.
Frontiers in Immunology (2017)
Understanding Autoimmune Diabetes through the Prism of the Tri-Molecular Complex
Matthew L. Bettini et al.
FRONTIERS IN ENDOCRINOLOGY (2017)
Single CD28 stimulation induces stable and polyclonal expansion of human regulatory T cells
Xuehui He et al.
SCIENTIFIC REPORTS (2017)
Transcriptional regulation of FOXP3 requires integrated activation of both promoter and CNS regions in tumor-induced CD8+ Treg cells
Sreeparna Chakraborty et al.
SCIENTIFIC REPORTS (2017)
The transcription factor Batf3 inhibits the differentiation of regulatory T cells in the periphery
Wonyong Lee et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2017)
Different molecular complexes that mediate transcriptional induction and repression by FoxP3
Ho-Keun Kwon et al.
NATURE IMMUNOLOGY (2017)
Immune deficiency and autoimmunity in patients with CTLA-4 (CD152) mutations
N. Verma et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2017)
Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 diabetes
S. Alice Long et al.
CELLULAR IMMUNOLOGY (2017)
Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments
Alessia Angelin et al.
CELL METABOLISM (2017)
Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity
Abigail E. Overacre-Delgoffe et al.
CELL (2017)
Proinflammatory cytokine interferon-γ and microbiome-derived metabolites dictate epigenetic switch between forkhead box protein 3 isoforms in coeliac disease
G. Serena et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2017)
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
Jason D. Fontenot et al.
JOURNAL OF IMMUNOLOGY (2017)
Helios Controls a Limited Subset of Regulatory T Cell Functions
Mathew Sebastian et al.
JOURNAL OF IMMUNOLOGY (2016)
Phenotypic, Functional, and Gene Expression Profiling of Peripheral CD45RA+and CD45RO+CD4+CD25+CD127(low) Treg Cells in Patients With Chronic Rheumatoid Arthritis
Gina J. Walter et al.
ARTHRITIS & RHEUMATOLOGY (2016)
Antigen-specificity using chimeric antigen receptors: the future of regulatory T-cell therapy?
Dominic Boardman et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2016)
Altered microRNA Expression and Immunosuppressive Cytokine Production by Regulatory T Cells of Ulcerative Colitis Patients
Mousa Mohammadnia-Afrouzi et al.
IMMUNOLOGICAL INVESTIGATIONS (2016)
Control of Foxp3 stability through modulation of TET activity
Xiaojing Yue et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Antigen exposure shapes the ratio between antigen-specific Tregs and conventional T cells in human peripheral blood
Laura F. Su et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Singular role for T-BET+ CXCR3+ regulatory T cells in protection from autoimmune diabetes
Tze Guan Tan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Regulatory T Cells in Patients with Idiopathic Thrombocytopenic Purpura
Alev Akyol Erikci et al.
TURKISH JOURNAL OF HEMATOLOGY (2016)
A Distinct Function of Regulatory T Cells in Tissue Protection
Nicholas Arpaia et al.
CELL (2015)
Analysis of CD8+ Treg cells in patients with ovarian cancer: a possible mechanism for immune impairment
Shuping Zhang et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2015)
Origin and functions of pro-inflammatory cytokine producing Foxp3+ regulatory T cells
Pushpa Pandiyan et al.
CYTOKINE (2015)
Divergent effects of type-I interferons on regulatory T cells
Silvia Piconese et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2015)
The Chromatin-Modifying Enzyme Ezh2 Is Critical for the Maintenance of Regulatory T Cell Identity after Activation
Michel DuPage et al.
IMMUNITY (2015)
Peripherally Induced Tolerance Depends on Peripheral Regulatory T Cells That Require Hopx To Inhibit Intrinsic IL-2 Expression
Andrew Jones et al.
JOURNAL OF IMMUNOLOGY (2015)
Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226
Christopher A. Fuhrman et al.
JOURNAL OF IMMUNOLOGY (2015)
Phenotypic Complexity of the Human Regulatory T Cell Compartment Revealed by Mass Cytometry
Gavin M. Mason et al.
JOURNAL OF IMMUNOLOGY (2015)
Super-enhancers delineate disease-associated regulatory nodes in T cells
Golnaz Vahedi et al.
NATURE (2015)
A mechanism for expansion of regulatory T-cell repertoire and its role in self-tolerance
Yongqiang Feng et al.
NATURE (2015)
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
Suna Onengut-Gumuscu et al.
NATURE GENETICS (2015)
The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment
Xuan Zhang et al.
NATURE MEDICINE (2015)
Type 1 diabetes immunotherapy using polyclonal regulatory T cells
Jeffrey A. Bluestone et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
MicroRNA-31 negatively regulates peripherally derived regulatory T-cell generation by repressing retinoic acid-inducible protein 3
Lingyun Zhang et al.
NATURE COMMUNICATIONS (2015)
Peripheral blood regulatory T cells in patients with diffuse systemic sclerosis (SSc) before and after autologous hematopoietic SCT: a pilot study
J. Baraut et al.
BONE MARROW TRANSPLANTATION (2014)
Influence of bacteria on epigenetic gene control
Kyoko Takahashi
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
miR-155 Activates Cytokine Gene Expression in Th17 Cells by Regulating the DNA-Binding Protein Jarid2 to Relieve Polycomb-Mediated Repression
Thelma M. Escobar et al.
IMMUNITY (2014)
tTregs, pTregs, and iTregs: similarities and differences
Ethan M. Shevach et al.
IMMUNOLOGICAL REVIEWS (2014)
Decreased expression of microRNA-21 correlates with the imbalance of Th17 and Treg cells in patients with rheumatoid arthritis
Liyang Dong et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2014)
Epigenetics and the microbiome: developing areas in the understanding of the aetiology of lupus
C. J. Edwards et al.
LUPUS (2014)
Pathogenic conversion of Foxp3(+) T cells into T(H)17 cells in autoimmune arthritis
Noriko Komatsu et al.
NATURE MEDICINE (2014)
A Special Population of Regulatory T Cells Potentiates Muscle Repair
Dalia Burzyn et al.
CELL (2013)
Super-Enhancers in the Control of Cell Identity and Disease
Denes Hnisz et al.
CELL (2013)
Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity
Kevin Goudy et al.
CLINICAL IMMUNOLOGY (2013)
Teplizumab (Anti-CD3 mAb) Treatment Preserves C-Peptide Responses in Patients With New-Onset Type 1 Diabetes in a Randomized Controlled Trial Metabolic and Immunologic Features at Baseline Identify a Subgroup of Responders
Kevan C. Herold et al.
DIABETES (2013)
Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response
Samantha L. Bailey-Bucktrout et al.
IMMUNITY (2013)
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
Yukihiro Furusawa et al.
NATURE (2013)
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
Nicholas Arpaia et al.
NATURE (2013)
Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication
Atsuya Nishiyama et al.
NATURE (2013)
Role of cytokines in tymus- versus peripherally derived-regulatory T cell differentiation and function
Jeremie David Goldstein et al.
FRONTIERS IN IMMUNOLOGY (2013)
Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells
Thomas Duhen et al.
BLOOD (2012)
An N-Terminal Mutation of the Foxp3 Transcription Factor Alleviates Arthritis but Exacerbates Diabetes
Jaime Darce et al.
IMMUNITY (2012)
Loss of Epigenetic Modification Driven by the Foxp3 Transcription Factor Leads to Regulatory T Cell Insufficiency
Matthew L. Bettini et al.
IMMUNITY (2012)
Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells
Takahisa Miyao et al.
IMMUNITY (2012)
Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut
Susan M. Schlenner et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
IFN-γ Production by Allogeneic Foxp3+ Regulatory T Cells Is Essential for Preventing Experimental Graft-versus-Host Disease
Christian Koenecke et al.
JOURNAL OF IMMUNOLOGY (2012)
Type 1 Diabetes-Associated IL2RA Variation Lowers IL-2 Signaling and Contributes to Diminished CD4+CD25+ Regulatory T Cell Function
Garima Garg et al.
JOURNAL OF IMMUNOLOGY (2012)
CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery
Moa Fransson et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Novel Foxo1-dependent transcriptional programs control Treg cell function
Weiming Ouyang et al.
NATURE (2012)
A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells
Wenxian Fu et al.
NATURE IMMUNOLOGY (2012)
Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
Matthew T. Maurano et al.
SCIENCE (2012)
An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4+ T cells
S. A. Long et al.
GENES AND IMMUNITY (2011)
Anti-CD3 Therapy Promotes Tolerance by Selectively Depleting Pathogenic Cells while Preserving Regulatory T Cells
Cristina Penaranda et al.
JOURNAL OF IMMUNOLOGY (2011)
IL-2 Controls the Stability of Foxp3 Expression in TGF-β-Induced Foxp3+ T Cells In Vivo
Qian Chen et al.
JOURNAL OF IMMUNOLOGY (2011)
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation
Marc Beyer et al.
NATURE IMMUNOLOGY (2011)
Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells
Yohsuke Harada et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
Ye Zheng et al.
NATURE (2010)
Dual function of CTLA-4 in regulatory T cells and conventional T cells to prevent multiorgan autoimmunity
Nitya Jain et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Quantification and phenotype of regulatory T cells in rheumatoid arthritis according to Disease Activity Score-28
Jose Miguel Sempere-Ortells et al.
AUTOIMMUNITY (2009)
Expansion of Human Regulatory T-Cells From Patients With Type 1 Diabetes
Amy L. Putnam et al.
DIABETES (2009)
Human natural Treg microRNA signature: Role of microRNA-31 and microRNA-21 in FOXP3 expression
Redouane Rouas et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
Nuclear Factor-κB Modulates Regulatory T Cell Development by Directly Regulating Expression of Foxp3 Transcription Factor
Meixiao Long et al.
IMMUNITY (2009)
In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression
Kylie E. Webster et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Induction of Foxp3 demethylation increases regulatory CD4(+)CD25(+) T cells and prevents the occurrence of diabetes in mice
Qanhui Zheng et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2009)
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
Xuyu Zhou et al.
NATURE IMMUNOLOGY (2009)
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
Meghan A. Koch et al.
NATURE IMMUNOLOGY (2009)
TGF-p-induced Foxp3+ regulatory T cells rescue scurfy mice
Eva N. Huter et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
DNA methylation controls Foxp3 gene expression
Julia K. Polansky et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
Human CD4 and CD8 regulatory T cells in infectious diseases and vaccination
Simone A. Joosten et al.
HUMAN IMMUNOLOGY (2008)
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
Qizhi Tang et al.
IMMUNITY (2008)
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
Xuexian O. Yang et al.
IMMUNITY (2008)
CD4+FoxP3+ regulatory T cells confer infectious tolerance in a TGF-β-dependent manner
John Andersson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Functional suppression by FoxP3(+)CD4(+)CD25(high) regulatory T cells during acute hepatitis C virus infection
Susan Smyk-Pearson et al.
JOURNAL OF INFECTIOUS DISEASES (2008)
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
Jafar Sharif et al.
NATURE (2007)
UHRF1 plays a role in maintaining DNA methylation in mammalian cells
Magnolia Bostick et al.
SCIENCE (2007)
CD8+ T cell-mediated suppression of autoimmunity in a murine lupus model of peptide-induced immune tolerance depends on Foxp3 expression
Ram Pyare Singh et al.
JOURNAL OF IMMUNOLOGY (2007)
Cutting edge:: IL-2 is essential for TGF-β-mediated induction of Foxp3+ T regulatory cells
Todd S. Davidson et al.
JOURNAL OF IMMUNOLOGY (2007)
Epigenetic control of the foxp3 locus in regulatory T cells
Stefan Floess et al.
PLOS BIOLOGY (2007)
FOXP3 controls regulatory T cell function through cooperation with NFAT
Yongqing Wu et al.
CELL (2006)
Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B1
Dongping Xu et al.
JOURNAL OF IMMUNOLOGY (2006)
Therapeutic potential of self-antigen-specific CD4+CD25+ regulatory T cells selected in vitro from a polyclonal repertoire
S Fisson et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice
EL Masteller et al.
JOURNAL OF IMMUNOLOGY (2005)
A single course of anti-CD3 monoclonal antibody hOKT3γ1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
KC Herold et al.
DIABETES (2005)
Regulatory T cell lineage specification by the forkhead transcription factor FoxP3
JD Fontenot et al.
IMMUNITY (2005)
Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes
S Lindley et al.
DIABETES (2005)
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
QZ Tang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
WJ Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ re latory thyrnocytes
L Cosmi et al.
BLOOD (2003)
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
JD Fontenot et al.
NATURE IMMUNOLOGY (2003)
Control of regulatory T cell development by the transcription factor Foxp3
S Hori et al.
SCIENCE (2003)
The amount of scurfin protein determines peripheral T cell number and responsiveness
R Khattri et al.
JOURNAL OF IMMUNOLOGY (2001)
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
RS Wildin et al.
NATURE GENETICS (2001)
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
ME Brunkow et al.
NATURE GENETICS (2001)
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
CL Bennett et al.
NATURE GENETICS (2001)