Journal
APPLIED SCIENCES-BASEL
Volume 12, Issue 12, Pages -Publisher
MDPI
DOI: 10.3390/app12125964
Keywords
intracranial aneurysm; arterial wall; hemodynamics
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Aneurysms are a focal or segmental disease of the arterial wall. Their formation and growth are influenced by genetic/environmental factors, altered structural and pathologic events, as well as interaction with the surrounding environment and luminal flow dynamics.
A considerable number of people harbor intracranial aneurysms (IA), which is a focal or segmental disease of the arterial wall. The pathophysiologic mechanisms of IAs formation, growth, and rupture are complex. The mechanism also differs with respect to the type of aneurysm. In broad aspects, aneurysms may be considered a disease of the vessel wall. In addition to the classic risk factors and the genetic/environmental conditions, altered structural and pathologic events along with the interaction of the surrounding environment and luminal flow dynamics contribute to the aneurysm's development and growth. In this review, we have tried to simplify the complex interaction of a multitude of events in relation to vessel wall in the formation and growth of IAs.
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