4.8 Review

Biomedical Photoacoustic Imaging for Molecular Detection and Disease Diagnosis: Always-On and Turn-On Probes

Related references

Note: Only part of the references are listed.
Article Nanoscience & Nanotechnology

DNA Origami-Anthraquinone Hybrid Nanostructures for In Vivo Quantitative Monitoring of the Progression of Tumor Hypoxia Affected by Chemotherapy

Yun Zeng et al.

Summary: In this study, we developed a DNA origami-based theranostic nanoplatform to explain the variation of tumor hypoxia during chemotherapy. Through in vitro and in vivo experiments, we demonstrated that the nanoplatform can release drugs and alleviate tumor hypoxia. Photoacoustic and fluorescence imaging were used to evaluate these effects.

ACS APPLIED MATERIALS & INTERFACES (2022)

Article Chemistry, Multidisciplinary

Reversibly Photoswitching Upconversion Nanoparticles for Super-Sensitive Photoacoustic Molecular Imaging

Cheng Liu et al.

Summary: This study introduced a novel method of photoacoustic photoswitching imaging using a nanoparticle-based probe, which significantly improved imaging sensitivity through reversible photoswitching technology, and successfully demonstrated imaging in living mice.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

Review Chemistry, Multidisciplinary

Chemical Design of Activatable Photoacoustic Probes for Precise Biomedical Applications

Yongchao Liu et al.

Summary: Photoacoustic imaging technology combines the advantages of optical and acoustic imaging, offering high imaging depth and resolution for molecular imaging. Activatable molecular PA probes show promise for real-time molecular visualization and precise biomedical diagnosis. These probes can alter their PA intensities upon reacting with specific targets or biological events, providing new possibilities for biomedical applications.

CHEMICAL REVIEWS (2022)

Article Multidisciplinary Sciences

In vivo three-dimensional multispectral photoacoustic imaging of dual enzyme-driven cyclic cascade reaction for tumor catalytic therapy

Shan Lei et al.

Summary: The study demonstrates the use of three-dimensional multispectral photoacoustic molecular imaging to monitor cascade catalytic therapy in vivo, and shows its potential application in tumor treatment.

NATURE COMMUNICATIONS (2022)

Article Engineering, Biomedical

Highly photostable croconium dye-anchored cell membrane vesicle for tumor pH-responsive duplex imaging-guided photothermal therapy

Xiaoting Gao et al.

Summary: The research focused on developing tumor acidic microenvironment-responsive theranostic agents. The highly photostable amphiphilic croconium dye-anchored red blood cell membrane vesicle (LET-5) showed enhanced NIRF and PA signals in the tumor acidic microenvironment, along with activated photothermal effect. The use of cell membrane-based vesicles improved the stability and blood circulation of the drug, resulting in better therapeutic outcomes in tumor treatment.

BIOMATERIALS (2021)

Article Radiology, Nuclear Medicine & Medical Imaging

Photoacoustic Molecular Imaging for the Identification of Lymph Node Metastasis in Head and Neck Cancer Using an Anti-EGFR Antibody-Dye Conjugate

Naoki Nishio et al.

Summary: This study evaluated the potential of using PAMI for photoacoustic imaging to identify LN metastasis in patients with HNSCC. Results showed that PAMI using IRDye800-labeled tumor-specific antibody may help identify occult LN metastasis perioperatively in HNSCC patients.

JOURNAL OF NUCLEAR MEDICINE (2021)

Article Chemistry, Multidisciplinary

Integration of Multitargeted Polymer-Based Contrast Agents with Photoacoustic Computed Tomography: An Imaging Technique to Visualize Breast Cancer Intratumor Heterogeneity

Lei Li et al.

Summary: The study presents a noninvasive hybrid imaging technology that can identify intratumor heterogeneity in breast cancer, using multitargeted and multiplexed patchy polymeric photoacoustic contrast agents combined with single-impulse panoramic photoacoustic computed tomography. This technology has been shown to have high molecular specificity and real-time detection capability for distinguishing different types of malignant cells within the same tumor.

ACS NANO (2021)

Article Chemistry, Multidisciplinary

Activatable NIR-II Plasmonic Nanotheranostics for Efficient Photoacoustic Imaging and Photothermal Cancer Therapy

Chunyu Zhou et al.

Summary: The study presents a transformable chain structure based on gold nanochains that can be activated in the tumor microenvironment, exhibiting strong NIR-II absorption and excellent properties for tumor treatment.

ADVANCED MATERIALS (2021)

Article Chemistry, Multidisciplinary

Dual Ratiometric SERS and Photoacoustic Core-Satellite Nanoprobe for Quantitatively Visualizing Hydrogen Peroxide in Inflammation and Cancer

Qingqing Li et al.

Summary: This study introduces a novel core-satellite gold nanostructure for dual imaging, enabling precise detection and differentiation of H2O2 in inflammation/cancer-related tissues. The nanoprobe can also be used for targeted drug delivery and real-time tracking of anti-inflammatory treatment progress.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

Activatable Polymeric Nanoprobe for Near-Infrared Fluorescence and Photoacoustic Imaging of T Lymphocytes

Yan Zhang et al.

Summary: The development of real-time non-invasive imaging probes for assessing infiltration and activation of cytotoxic T cells (CTLs) is essential for predicting the efficacy of cancer immunotherapy. This study introduces an activatable semiconducting polymer nanoprobe (SPNP) for near-infrared fluorescence (NIRF) and photoacoustic (PA) imaging of a CTL activation biomarker, granzyme B. The SPNP can passively target tumors and react with granzyme B in situ to release a dye-labeled peptide, resulting in correlated NIRF and PA signals with the expression level of granzyme B and intratumoral population of CTLs.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Biophysics

Recent progress in near-infrared photoacoustic imaging

Jinya Du et al.

Summary: The emergence of photoacoustic imaging (PAI) has greatly expanded the application of biomolecules bioimaging, especially in near-infrared (NIR) PAI which shows great potential in biomedical applications. Comparing different imaging modalities and focusing on the strategies used to improve contrast and performance in NIR-PAI are essential for enhancing imaging accuracy. Challenges and prospects in accelerating the development of PAI are identified to attract more researchers in this field.

BIOSENSORS & BIOELECTRONICS (2021)

Article Multidisciplinary Sciences

Chain-like gold nanoparticle clusters for multimodal photoacoustic microscopy and optical coherence tomography enhanced molecular imaging

Van Phuc Nguyen et al.

Summary: This study presents a new type of ultrapure chain-like gold nanoparticle (CGNP) clusters with excellent biocompatibility and photostability. Upon validation in living rabbits after conjugation with RGD peptides, they demonstrate a 17-fold increase in PAM signal and a 176% increase in OCT signal, showing their potential for in vivo imaging.

NATURE COMMUNICATIONS (2021)

Article Chemistry, Multidisciplinary

Photoacoustic imaging of elevated glutathione in models of lung cancer for companion diagnostic applications

Melissa Y. Lucero et al.

Summary: Companion diagnostics are powerful tests that improve treatment outcomes by matching therapies to patients. A photoacoustic imaging-based CDx (PACDx) has been developed for the selective detection of elevated glutathione (GSH) in lung cancer patients. The matched prodrug PARx can inhibit tumor growth in a lung cancer model without off-target toxicity.

NATURE CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Exosome-based photoacoustic imaging guided photodynamic and immunotherapy for the treatment of pancreatic cancer

Yongho Jang et al.

Summary: In this study, tumor-derived reassembled exosome (R-Exo) was used both as a drug delivery carrier and an immunostimulatory agent for cancer therapy. By loading chlorin e6 photosensitizer into R-Exo, it retained its original size and membrane proteins for targeting tumor cells. The modified exosomes were able to generate reactive oxygen species and increase cytokine release from immune cells, showing their potential as an immunotherapeutic agent.

JOURNAL OF CONTROLLED RELEASE (2021)

Article Nanoscience & Nanotechnology

Photoacoustic molecular imaging-escorted adipose photodynamic-browning synergy for fighting obesity with virus-like complexes

Ronghe Chen et al.

Summary: Photodynamic therapy and adipose browning induction are two promising approaches to reverse obesity, with the former acting rapidly and locally, and the latter having a more gradual and widespread effect. Despite their complementarity, they have rarely been combined and imaged non-invasively in vivo.

NATURE NANOTECHNOLOGY (2021)

Review Chemistry, Multidisciplinary

Optical Imaging in the Second Near Infrared Window for Vascular Bioimaging

Zi'an Wang et al.

Summary: This review summarizes the latest progress of NIR-II optical imaging for angiography, including fluorescence imaging, photoacoustic imaging, and optical coherence tomography. It highlights the optimization and application of probes in vascular imaging.

SMALL (2021)

Article Engineering, Biomedical

NAD(P)H-triggered probe for dual-modal imaging during energy metabolism and novel strategy of enhanced photothermal therapy in tumor

Yang Tian et al.

Summary: The article introduces the successful visualization of NAD(P)H in tumor cells and bacteria using a novel multifunctional probe Cy-N, as well as the imaging of NAD(P)H in tumor-bearing mice through dual-modal imaging. It also proposes a new strategy for photothermal therapy based on NAD(P)H.

BIOMATERIALS (2021)

Article Chemistry, Multidisciplinary

Development of NIR-II Photoacoustic Probes Tailored for Deep-Tissue Sensing of Nitric Oxide

Melissa Y. Lucero et al.

Summary: Photoacoustic imaging using near infrared I light has limitations due to interference from endogenous biomolecules, prompting the development of NIR-II imaging agents for improved sensitivity. The study introduced APNO-1080 as a NIR-II nitric oxide-responsive probe, demonstrating enhanced sensitivity and deep-tissue imaging capabilities in vitro and in vivo models of cancer.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Multidisciplinary

Ratiometric Semiconducting Polymer Nanoparticle for Reliable Photoacoustic Imaging of Pneumonia-Induced Vulnerable Atherosclerotic Plaque in Vivo

Yuan Ma et al.

Summary: The developed RSPN nanoparticles in this study can accurately assess the rupture risk of vulnerable plaque caused by acute pneumonia and successfully reflect the oxidative stress level in vulnerable plaque, providing a promising approach to reduce the mortality of atherosclerotic-induced cardiovascular disease.

NANO LETTERS (2021)

Article Chemistry, Analytical

Proximity-Induced Hybridization Chain Reaction-Based Photoacoustic Imaging System for Amplified Visualization Protein-Specific Glycosylation in Mice

Zhenhua Liu et al.

Summary: A study demonstrated a photoacoustic nanoprobe for amplified visual detection of protein-specific glycosylation in vivo, using a proximity-induced hybridization chain reaction. This technique allowed real-time detection of MUC1-specific glycosylation in mice with breast cancer and successfully monitored its dynamic states during tunicamycin treatment.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Analytical

Cathepsin B-Activated Fluorescent and Photoacoustic Imaging of Tumor

Xiaoxia Chen et al.

Summary: The study focused on the development of two CTB-activated FL/PA probes, demonstrating high sensitivity and spatial resolution in monitoring CTB activity in vivo. HCy-Cit-Val showed superior performance and is envisioned to be suitable for clinical early diagnosis of CTB-related cancer in the near future.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Analytical

Activatable Photoacoustic Probe for In Situ Imaging of Endogenous Carbon Monoxide in the Murine Inflammation Model

Wenxiu Li et al.

Summary: Photoacoustic imaging, combining the advantages of optical and ultrasound imaging, is a promising tool for monitoring the steady-state changes of carbon monoxide (CO) in living organisms. A newly developed activatable PA probe, MTR-CO, showed high sensitivity, specificity, and biocompatibility for CO detection in vivo, providing a potential strategy for disease monitoring.

ANALYTICAL CHEMISTRY (2021)

Article Biochemical Research Methods

MMP-2-Activatable Photoacoustic Tumor Imaging Probes Based on Al- and Si-Naphthalocyanines

Koji Miki et al.

Summary: Enzyme-activatable photoacoustic probes based on aluminum and silicon naphthalocyanines were designed and synthesized, showing enhanced PA signal intensity ratios after incubation with MMP-2. These conjugates can serve as powerful contrast agents to visualize diseases with specific enzyme overexpression, demonstrating their potential in in vitro and in vivo imaging experiments.

BIOCONJUGATE CHEMISTRY (2021)

Article Engineering, Biomedical

Versatile gadolinium(III)-phthalocyaninate photoagent for MR/PA imaging-guided parallel photocavitation and photodynamic oxidation at single-laser irradiation

Ruijing Zhang et al.

Summary: The new GdPc-enabled PADT combines photoacoustic and photodynamic therapy to effectively inhibit solid tumors under normal or hypoxic conditions, utilizing a single pulsed laser to maximize therapeutic efficacy and surpass conventional PDT.

BIOMATERIALS (2021)

Article Acoustics

High-resolution functional photoacoustic monitoring of vascular dynamics in human fingers

Joongho Ahn et al.

Summary: By utilizing high-resolution photoacoustic monitoring of vascular dynamics in human fingers, important information can be obtained for measuring heart rate, oxygen consumption, and blood perfusion in peripheral vascular examination.

PHOTOACOUSTICS (2021)

Review Materials Science, Biomaterials

Phthalocyanine-based photoacoustic contrast agents for imaging and theranostics

Bing-De Zheng et al.

Summary: Phthalocyanine, an organic dye, is a compound that has garnered attention for its high molar absorption coefficient in the near-infrared region. Various strategies have been implemented to enhance the photoacoustic effect of phthalocyanine-based contrast agents, such as increasing water solubility, changing spectral properties, prolonging circulation time, and improving targeting. The application of these contrast agents in biomedical imaging and image-guided phototherapy is explored, along with the prospects and challenges in this field.

BIOMATERIALS SCIENCE (2021)

Review Chemistry, Multidisciplinary

Emerging contrast agents for multispectral optoacoustic imaging and their biomedical applications

Yinglong Wu et al.

Summary: Optoacoustic imaging is a hybrid biomedical imaging technique that uses contrast agents to generate ultrasound waves in tissues, producing high-resolution images. Multispectral optoacoustic imaging can discriminate signals from different contrast agents and enable specific agent identification in tissues, as well as simultaneous molecular and physiological imaging. Contrast agents play essential roles in optoacoustic imaging, with various new agents being explored and applied in recent years.

CHEMICAL SOCIETY REVIEWS (2021)

Article Chemistry, Multidisciplinary

Design and synthesis of a ratiometric photoacoustic imaging probe activated by selenol for visual monitoring of pathological progression of autoimmune hepatitis

Chaobang Zhang et al.

Summary: Photoacoustic imaging is a robust biomedical imaging technique that combines the high contrast of optical imaging and the high spatial resolution of ultrasound imaging. An innovative ratiometric PA imaging probe APSel was developed for monitoring the pathological progress of autoimmune hepatitis, offering a new tool for studying and diagnosing AIH diseases.

CHEMICAL SCIENCE (2021)

Review Chemistry, Multidisciplinary

Second near-infrared photothermal materials for combinational nanotheranostics

Cheng Xu et al.

Summary: Second near-infrared photothermal therapy (NIR-II PTT) has advantages of deeper penetration and less toxicity, but faces challenges of suboptimal photothermal conversion and limited therapeutic efficacy. To improve efficacy, multifunctional NIR-II photothermal inorganic or organic materials have been developed for combination with other therapeutic modalities.

CHEMICAL SOCIETY REVIEWS (2021)

Article Biochemical Research Methods

Photoacoustic imaging of the human placental vasculature

Efthymios Maneas et al.

JOURNAL OF BIOPHOTONICS (2020)

Article Nanoscience & Nanotechnology

Poly(ionic liquid)-Gated CuCo2S4 for pH-/Thermo-Triggered Drug Release and Photoacoustic Imaging

Shao-Ying Fan et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Article Chemistry, Multidisciplinary

Supramolecular Phthalocyanine Assemblies for Improved Photoacoustic Imaging and Photothermal Therapy

Xingshu Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Multidisciplinary

An Activatable Polymeric Reporter for Near-Infrared Fluorescent and Photoacoustic Imaging of Invasive Cancer

Qing Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Multidisciplinary

Photothermal-Promoted Morphology Transformation in Vivo Monitored by Photoacoustic Imaging

Xue-Hao Zhang et al.

NANO LETTERS (2020)

Article Multidisciplinary Sciences

Maltotriose-based probes for fluorescence and photoacoustic imaging of bacterial infections

Aimen Zlitni et al.

NATURE COMMUNICATIONS (2020)

Article Nanoscience & Nanotechnology

Pickering Bubbles as Dual-Modality Ultrasound and Photoacoustic Contrast Agents

Al de Leon et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Article Chemistry, Multidisciplinary

Fluoro-Photoacoustic Polymeric Renal Reporter for Real-Time Dual Imaging of Acute Kidney Injury

Penghui Cheng et al.

ADVANCED MATERIALS (2020)

Article Chemistry, Multidisciplinary

Structure-inherent near-infrared bilayer nanovesicles for use as photoacoustic image-guided chemo-thermotherapy

Ilkoo Noh et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Article Materials Science, Multidisciplinary

Tuning Optical Properties of BODIPY Dyes by Pyrrole Conjugation for Photoacoustic Imaging

Jean Michel Merkes et al.

ADVANCED OPTICAL MATERIALS (2020)

Review Chemistry, Multidisciplinary

Engineering Plasmonic Nanoparticles for Enhanced Photoacoustic Imaging

Yash Mantri et al.

ACS NANO (2020)

Article Chemistry, Analytical

Mitochondria-Targeted Fluorescent and Photoacoustic Imaging of Hydrogen Peroxide in Inflammation

Xiaoxia Chen et al.

ANALYTICAL CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

Manganese(II) Texaphyrin: A Paramagnetic Photoacoustic Contrast Agent Activated by Near-IR Light

Yaguang Ren et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Materials Science, Biomaterials

Facile Preparation of Phthalocyanine-Based Nanodots for Photoacoustic Imaging and Photothermal Cancer Therapy In Vivo

Fengshou Wu et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)

Article Materials Science, Biomaterials

Contrast-Enhanced Multispectral Photoacoustic Imaging for Irregular Hepatectomy Navigation: A Pilot Study

Yueming Zhang et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)

Article Chemistry, Multidisciplinary

A Photoacoustic Probe for the Imaging of Tumor Apoptosis by Caspase-Mediated Macrocyclization and Self-Assembly

Yuqi Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Nanoscience & Nanotechnology

Miniature gold nanorods for photoacoustic molecular imaging in the second near-infrared optical window

Yun-Sheng Chen et al.

NATURE NANOTECHNOLOGY (2019)

Article Multidisciplinary Sciences

Bioengineered bacterial vesicles as biological nano-heaters for optoacoustic imaging

Vipul Gujrati et al.

NATURE COMMUNICATIONS (2019)

Article Chemistry, Multidisciplinary

Design of Photostable, Activatable Near-Infrared Photoacoustic Probes Using Tautomeric Benziphthalocyanine as a Platform

Naoyuki Toriumi et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

A Magneto-Optical Nanoplatform for Multimodality Imaging of Tumors in Mice

Guosheng Song et al.

ACS NANO (2019)

Article Chemistry, Multidisciplinary

In Vivo Photoacoustic Tracking of Mesenchymal Stem Cell Viability

Kabir S. Dhada et al.

ACS NANO (2019)

Article Chemistry, Multidisciplinary

Thermoresponsive Semiconducting Polymer Nanoparticles for Contrast-Enhanced Photoacoustic Imaging

Dong Cui et al.

ADVANCED FUNCTIONAL MATERIALS (2019)

Article Chemistry, Multidisciplinary

Plasmonic Photothermal Nanoparticles for Biomedical Applications

Minho Kim et al.

ADVANCED SCIENCE (2019)

Review Acoustics

Photoacoustic clinical imaging

Idan Steinberg et al.

PHOTOACOUSTICS (2019)

Review Acoustics

Current and future trends in photoacoustic breast imaging

Srirang Manohar et al.

PHOTOACOUSTICS (2019)

Article Nanoscience & Nanotechnology

Activatable Hybrid Polyphosphazene-AuNP Nanoprobe for ROS Detection by Bimodal PA/CT Imaging

Mathilde Bouche et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Article Chemistry, Multidisciplinary

Nitric Oxide-Activated Dual-Key-One-Lock Nanoprobe for in Vivo Molecular Imaging and High-Specificity Cancer Therapy

Lili Teng et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Chemistry, Multidisciplinary

Dynamic-Reversible Photoacoustic Probe for Continuous Ratiometric Sensing and Imaging of Redox Status in Vivo

Judun Zheng et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Nanoscience & Nanotechnology

Ratiometric Photoacoustic Nanoprobe for Bioimaging of Cu2+

Sheng Wang et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Review Chemistry, Multidisciplinary

Photoacoustic Imaging: Contrast Agents and Their Biomedical Applications

Qinrui Fu et al.

ADVANCED MATERIALS (2019)

Article Chemistry, Multidisciplinary

Metabolizable Semiconducting Polymer Nanoparticles for Second Near-Infrared Photoacoustic Imaging

Yuyan Jiang et al.

ADVANCED MATERIALS (2019)

Article Chemistry, Multidisciplinary

A Water-Soluble, NIR-Absorbing Quaterrylenediimide Chromophore for Photoacoustic Imaging and Efficient Photothermal Cancer Therapy

Chang Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Review Acoustics

A review of clinical photoacoustic imaging: Current and future trends

Amalina Binte Ebrahim Attia et al.

PHOTOACOUSTICS (2019)

Article Chemistry, Multidisciplinary

A 1064 nm excitable semiconducting polymer nanoparticle for photoacoustic imaging of gliomas

Yanqing Yang et al.

NANOSCALE (2019)

Article Pharmacology & Pharmacy

Indocyanine Green-Coated Gold Nanoclusters for Photoacoustic Imaging and Photothermal Therapy

Elizabeth Higbee-Dempsey et al.

ADVANCED THERAPEUTICS (2019)

Article Materials Science, Biomaterials

Efficient photoacoustic imaging using indocyanine green (ICG) loaded functionalized mesoporous silica nanoparticles

Zanib Chaudhary et al.

BIOMATERIALS SCIENCE (2019)

Article Nanoscience & Nanotechnology

Highly Stable Conjugated Polymer Dots as Multifunctional Agents for Photoacoustic Imaging-Guided Photothermal Therapy

Kaiwen Chang et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

Article Biochemistry & Molecular Biology

Photophysical Tuning of N-Oxide-Based Probes Enables Ratiometric Photoacoustic Imaging of Tumor Hypoxia

Hailey J. Knox et al.

ACS CHEMICAL BIOLOGY (2018)

Article Chemistry, Multidisciplinary

Nanoparticles of Chlorin Dimer with Enhanced Absorbance for Photoacoustic Imaging and Phototherapy

Xiaohua Zheng et al.

ADVANCED FUNCTIONAL MATERIALS (2018)

Article Chemistry, Analytical

A Dual-Modal Molecular Probe for Near-Infrared Fluorescence and Photoacoustic Imaging of Peroxynitrite

Jianjian Zhang et al.

ANALYTICAL CHEMISTRY (2018)

Review Chemistry, Multidisciplinary

Photoacoustic Probes for Molecular Detection: Recent Advances and Perspectives

Leli Zeng et al.

SMALL (2018)

Article Medicine, Research & Experimental

Mesoporous Carbon Nanospheres as a Multifunctional Carrier for Cancer Theranostics

Libo Zhou et al.

THERANOSTICS (2018)

Article Materials Science, Biomaterials

Enhancing hydrophilicity of photoacoustic probes for effective ratiometric imaging of hydrogen peroxide

Xiaomei Lu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

Article Medicine, Research & Experimental

Tyrosinase-Based Reporter Gene for Photoacoustic Imaging of MicroRNA-9 Regulated by DNA Methylation in Living Subjects

Haifeng Zheng et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2018)

Article Chemistry, Multidisciplinary

An Asymmetrical Cyanine Dye Nanoparticles for Small Vessel Photoacoustic Imaging In Vivo

Yunzheng Li et al.

CHEMNANOMAT (2018)

Article Chemistry, Multidisciplinary

An active DNA-based nanoprobe for photoacoustic pH imaging

Kevin N. Baumann et al.

CHEMICAL COMMUNICATIONS (2018)

Article Polymer Science

Development of Semiconducting Polymer Nanoparticles for Photoacoustic Imaging

Dong Cui et al.

MACROMOLECULAR RAPID COMMUNICATIONS (2017)

Article Chemistry, Multidisciplinary

Copper Sulfide Perfluorocarbon Nanodroplets as Clinically Relevant Photoacoustic/Ultrasound Imaging Agents

Daniela Y. Santiesteban et al.

NANO LETTERS (2017)

Article Multidisciplinary Sciences

A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia

Hailey J. Knox et al.

NATURE COMMUNICATIONS (2017)

Article Materials Science, Biomaterials

Real-Time and Multiplexed Photoacoustic Imaging of Internally Normalized Mixed-Targeted Nanoparticles

Hoang D. Lu et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)

Article Materials Science, Biomaterials

Real-Time and Multiplexed Photoacoustic Imaging of Internally Normalized Mixed-Targeted Nanoparticles

Hoang D. Lu et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)

Article Chemistry, Multidisciplinary

Ratiometric Photoacoustic Molecular Imaging for Methylmercury Detection in Living Subjects

Yi Liu et al.

ADVANCED MATERIALS (2017)

Article Nanoscience & Nanotechnology

Amphiphilic Semiconducting Oligomer for Near-Infrared Photoacoustic and Fluorescence Imaging

Chao Yin et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

Article Chemistry, Multidisciplinary

Self-Assembly of Semiconducting Polymer Amphiphiles for In Vivo Photoacoustic Imaging

Chen Xie et al.

ADVANCED FUNCTIONAL MATERIALS (2017)

Article Nanoscience & Nanotechnology

Glucose-Derived Carbonaceous Nanospheres for Photoacoustic Imaging and Photothermal Therapy

Zhao-Hua Miao et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

Article Nanoscience & Nanotechnology

Gold-Nanorods-Based Gene Carriers with the Capability of Photoacoustic Imaging and Photothermal Therapy

Jie Chen et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

Article Chemistry, Analytical

Near-Infrared Photoacoustic Imaging Probe Responsive to Calcium

Anurag Mishra et al.

ANALYTICAL CHEMISTRY (2016)

Article Chemistry, Multidisciplinary

Magneto-Plasmonic Janus Vesicles for Magnetic Field-Enhanced Photoacoustic and Magnetic Resonance Imaging of Tumors

Yijing Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Biochemical Research Methods

Axial PEGylation of Tin Octabutoxy Naphthalocyanine Extends Blood Circulation for Photoacoustic Vascular Imaging

Haoyuan Huang et al.

BIOCONJUGATE CHEMISTRY (2016)

Article Nanoscience & Nanotechnology

Indocyanine Green Loaded Reduced Graphene Oxide for In Vivo Photoacoustic/Fluorescence Dual-Modality Tumor Imaging

Jingqin Chen et al.

NANOSCALE RESEARCH LETTERS (2016)

Review Biochemical Research Methods

Contrast agents for molecular photoacoustic imaging

Judith Weber et al.

NATURE METHODS (2016)

Article Nanoscience & Nanotechnology

Indocyanine Green Loaded Reduced Graphene Oxide for In Vivo Photoacoustic/Fluorescence Dual-Modality Tumor Imaging

Jingqin Chen et al.

NANOSCALE RESEARCH LETTERS (2016)

Review Acoustics

Photoacoustic imaging of the eye: A mini review

Wenzhong Liu et al.

PHOTOACOUSTICS (2016)

Article Chemistry, Multidisciplinary

Oligo(ethylene glycol)-Based Thermosensitive Dendrimers and Their Tumor Accumulation and Penetration

Wei Wu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Article Chemistry, Multidisciplinary

Deep-Tissue Photoacoustic Tomography of a Genetically Encoded Near-Infrared Fluorescent Probe

Grigory S. Filonov et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)