Impact of Nanolayered Material and Nanohybrid Modifications on Their Potential Antibacterial Activity

Due to an escalating increase in multiple antibiotic resistance among bacteria, novel nanomaterials with antimicrobial properties are being developed to prevent infectious diseases caused by bacteria that are common in wastewater and the environment. A series of nanolayered structures and nanohybrids were prepared and modified by several methods including an ultrasonic technique, intercalation reactions of fatty acids, and carbon nanotubes, in addition to creating new phases based on zinc and aluminum. The nanomaterials prepared were used against a group of microorganisms, including E. coli, S. aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa. Experimental results revealed that a nanohybrid based on carbon nanotubes and fatty acids showed significant antimicrobial activity against E. coli, and can be implemented in wastewater treatment. Similar behavior was observed for a nanolayered structure which was prepared using ultrasonic waves. For the other microorganisms, a nanolayered structure combined with carbon nanotubes showed a significant and clear inhibitory effect on S. aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa. It is concluded that the nanolayered structures and nanohybrids, which can be modified at low cost with high productivity, using simple operations and straightforward to use equipment, can be considered good candidates for preventing infectious disease and inhibiting the spread of bacteria, especially those that are commonly found in wastewater and the environment.

Automated summary

Novel nanomaterials with antimicrobial properties are being developed to prevent infectious diseases caused by antibiotic-resistant bacteria commonly found in wastewater and the environment. Nanohybrids based on carbon nanotubes and fatty acids were found to be effective against E. coli, while nanolayered structures prepared using ultrasonic waves showed inhibitory effects on S. aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa. These nanomaterials, which can be modified at low cost with high productivity and simple operations, have great potential for preventing infectious diseases and inhibiting the spread of bacteria.